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  • The parabrachial nucleus contains separate populations of neurons that respond to elevated CO2 with EEG arousal and increased breathing. Here we report that the parabrachial respiratory neurons express FoxP2 and are required for respiratory responses to elevated CO2.

    • Satvinder Kaur
    • Nicole Lynch
    • Clifford B. Saper
    ArticleOpen Access
  • While our brain is primarily composed of lipids, their functions have largely remained unexplored. Here, authors show that specific lipids can be linked to the structural organization and functional hierarchy of the human and macaque brain.

    • Maria Osetrova
    • Anna Tkachev
    • Philipp Khaitovich
    ArticleOpen Access
  • Reconstructing the structure of a complex networked system and predicting its time evolution to understand its functions are usually two subjects that are treated separately. The authors propose a theoretical framework based on information theory, that uncovers the relation between reconstructability and predictability in networked systems.

    • Charles Murphy
    • Vincent Thibeault
    • Patrick Desrosiers
    ArticleOpen Access
  • Photoluminescence from plasmonic nanostructures exhibits diverse wavelength dependent nonlinear behaviors with debated origins. Here, authors use plasmonic gap mode resonators with precise nanoscale confinement to show this nonlinear emission can become dominated by non-Fermi carrier contributions.

    • Robert Lemasters
    • Manoj Manjare
    • Hayk Harutyunyan
    ArticleOpen Access
  • Assessing failure pressure is critical in determining pipeline integrity. In this study, based on the unified yield criterion, authors propose a limit state equation for steel pipes under various loads which can be converted into a series of failure pressure evaluation models for pipeline with different yield criteria.

    • Ming-ming Sun
    • Hong-yuan Fang
    • Ke-Jie Zhai
    ArticleOpen Access
  • Intelligent agents can perform two types of behavior, habitual and goal-directed. The authors propose a deep learning framework using a variational Bayes approach, which computationally explains many aspects of the interaction between the two types of behaviors in sensorimotor tasks.

    • Dongqi Han
    • Kenji Doya
    • Jun Tani
    ArticleOpen Access
  • Polaritons – hybrid light-matter excitations – in van der Waals materials hold promise for photonics applications below the diffraction limit. Here, the authors demonstrate in-plane steering and cloaking of phonon polaritons in assembled micro-structures based on α-MoO3 films with misaligned crystallographic orientations.

    • Hanchao Teng
    • Na Chen
    • Qing Dai
    ArticleOpen Access
  • Despite the importance of Rab GTPases in maintaining the integrity of vesicle trafficking, their physiological roles are not well understood. Here, the authors define a role for Rab30 in supporting lipid homeostasis during fasting in the mouse.

    • Danielle M. Smith
    • Brian Y. Liu
    • Michael J. Wolfgang
    ArticleOpen Access
  • Switchable structural and physical bistability in ferroelectric materials can be achieved as result of molecular orbital breaking. Here, the authors describe the photo-mediated bistability in organosilicon Schiff base ferroelectric crystals for the modulation of dielectric, second-harmonic generation, and ferroelectric polarization and showing good in vitro biocompatibility.

    • Zhu-Xiao Gu
    • Nan Zhang
    • Han-Yue Zhang
    ArticleOpen Access