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Current methods for auto-transfusion often result in disturbances to the patient’s blood homeostasis, leading to an increased bleeding risk. Here, the authors develop heparin-mimicking self-anticoagulant sponges for safe and convenient whole blood auto-transfusion, and study underlying mechanisms.
CO electroreduction to valuable high-energy content fuels is desired yet improving multicarbon C3 selectivity remains challenging. Here, authors enhance the n-propanol formation on a Cu-based electrocatalyst by introducing Pb atoms into the Cu lattice to induce Pb-rich Cu grain boundary sites.
Obstructive sleep apnea (OSA) is a highly prevalent condition with a number of comorbidities, but it has a high misdiagnosis rate. In this retrospective study, the authors used six independent databases to develop and evaluate a deep learning model, denoted OxiNet, for the diagnosis of OSA from the sole oximetry signal.
Extracellular vesicles (EVs) are important in plant-microbe interactions. Here we show that the divergent sequences within tetraspanins localized at EV membranes enable plant innate immune system to distinguish between self and non-self EVs.
Polymer electrolytes are attractive candidates for rechargeable lithium metal batteries. Here, the authors give a personal reflection on the structural design of coupled and decoupled polymer electrolytes and possible routes to further enhance their performance in rechargeable batteries.
Fluorescent proteins can report on many cellular variables. Here, authors develop a method for reporting high local densities, and use it to show that density distribution of heterochromatin in mouse embryonic stem cells are not in a liquid phase.
Why anxious individuals fail to control emotional behaviour is not well understood. Here, the authors show that highly anxious individuals have a more excitable lateral frontopolar cortex, and fail to recruit this region during emotional action control.
The authors present a generation-elimination framework that correlates the spectra from different frequency bands, where the inaccessible spectra are precisely forecasted without consulting structural information. The spectral correlation will accelerate the unification of all metasurface designs and facilitate versatile applications involving cross-wavelength information correlation.
Biorefinery lignin waste has little value in the market. Here, Liu et al. find that water-soluble lignin, converted from sulfuric acid lignin, improves plant iron bioavailability and growth through a metal chelating capacity comparable to the metal chelator EDTA.
Heterogeneous battery strategy, with each province flexibly choosing different battery strategies, achieves the lowest power system costs. However, this non-uniform strategy only achieves the lowest CO2 emissions at extremely high carbon prices.
Data on antibody response to SARS-CoV-2 in infants directly compared with their mothers is limited. Stoddard et al. find distinct antibody profiles in infants, including elevated levels of antibody binding to Spike, elevated ADCC, and convergent antibody binding escape profiles in the Spike fusion peptide.
Zebrafish can regenerate after paralyzing spine injuries and regain locomotor ability, unlike mammals. Here authors show that the neurogenic factor Hb-egf promotes spinal cord regeneration in zebrafish and is regulated by an enhancer that can similarly direct expression in the pro-regenerative setting of neonatal mice.
Nanoparticle-based drug delivery systems have shown potential for treating malignant tumors, however, limited tumor penetration of nanosystems remains a hurdle for effective tumor therapy. Here, the authors report a biomimetic bubble nanomachine with tumor-cell-membrane-derived nanovesicle secretion triggered by near-infrared laser irradiation for enhanced tumor penetration.
3-finger toxins are unique to the venoms of caenophidian snakes. This study traces the evolution of these toxins in snakes, highlighting a key shift from membrane-bound to secretory proteins. This transformation, involving the loss of a membrane-anchoring domain and changes in gene expression, paved the way for their venomous function.
Resistance to herbicide glyphosate can be evolved trough copy number variation (CNV) of its target gene EPSPS in goosegrass. Here, the authors assemble the genomes of glyphosate susceptible and resistance lines and provide evidence of sub-telomeric-repeat driven CNV of EPSPS could lead to glyphosate resistance.
Room temperature phosphorescent materials have potential in flexible electronics and photonics, but it is challenging to achieve desirable material properties. Here, the authors report stretchable, lightweight and multicoloured room temperature phosphorescent elastomers.
The application of time-resolved photoemission electron microscopy (TR-PEEM) to non-conducting materials is challenging. Here, the authors report the TR-PEEM characterization of near-field dielectric modes and photoemission properties of insulating hexagonal boron nitride structures on indium tin oxide/glass substrates.