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Spin-based sensors have attracted attention due to their high sensitivities. Here authors present a fullerene-based nano spin sensor for in-situ sensing of gas adsorption in porous organic frameworks, demonstrating the potential applications of molecular spin systems in quantum sensing.
Here, the authors use paleogenomic data from the indigenous people of the Canary Islands to shed light on the Prehistory of North Africa, and on how insularity and resources availability shaped the genetic composition of this isolated population.
It is challenging to increase carrier mobility in n-type Mg3(Bi,Sb)2 due to grain-boundary scattering. Here, authors reported a facile growth of coarse-grained Mg3(Bi,Sb)2 crystals with high carrier mobility. The as-fabricated module shows cooling performance comparable to commercial Bi2Te3 module.
The impacts of COVID-19 have been more severe in certain population groups, including migrants. In this total-population study from Sweden, the authors investigate the association between country of birth and COVID-19 related hospitalisation and death and describe how it changed over the first two years of the pandemic.
Membranes can be used for energy efficient organic liquid mixture separations. Here the authors use machine learning and transport simulations to predict the separation of complex mixtures such as crude oils by any linear polymer membrane.
Here, Bergant et al. provide evidence that Influenza A viruses cause alternative polyadenylation of host mRNAs and abrogation of this function leads to an attenuated phenotype in mice. This may constitute a general immune evasive mechanism employed by a variety of pathogenic viruses.
The neural mechanisms responsible for cold defense regulation are still unclear. Here, authors show parallel thermogenic pathways from the brain stem to the hypothalamus work together to enable resilience to cold temperature exposure and hypothermia.
Real-time monitoring of coatings erosive wear is critical to mitigate safety and financial concerns in many applications. Here, authors show a non-destructive inspection system with AI-enabled microwave resonators and a smart monitoring circuitry to identify and estimate wear depth and rate of eroded layers.
Vegetation resilience to drought is underlain by plant physiological responses. Here, the authors combine remote sensing data, explainable machine learning and model simulations to map global vegetation responses to drought linked to physiological processes such as stomatal regulation and light use efficiency.
Base editing technology has great potential in treating pathogenic single-nucleotide variations. Using a dual-AAV base editing system, Wu et al. restored visual functions in a mouse model of retinitis pigmentosa.
Many molecularly classified retinal cell types lack spatial information. Here, authors used MERFISH to create a spatial atlas of the mouse retina, leveraging co-embedding with scRNA-seq to explore spatially dependent gene expression in retinal cell subtypes.
Most DNA-encoded library (DEL) syntheses are limited by the presence of sensitive DNA-based constructs. Here, the authors develop DOSEDO, a diverse 3.7 million compound DEL, generated through diversity-oriented synthesis that provides enhanced scaffold and exit vector diversity and gives validated binding hits for multiple protein targets.
Liposome-mediated gene editing was used to abolish a mutation in gene Atp2b2 and recover hearing in a mouse model of dominant deafness. Editing was also used to target two mutations to recover hearing. The study detected large deletions due to editing.
The coalescence of nuclei plays an important role in phase transitions, but it remains challenging to monitor the process in real time. Here, Peng et al. image the coalescence of two post-critical nuclei in the crystal-crystal transition with single-particle resolution using a colloidal system.
Frameworks containing flexible macrocycle units provide opportunities in molecular recognition and separation. Here authors present MOFs with uniformly embedded pillar[5]arene that can recognise paraquat and 1,2,4,5-tetracyanobenzene in solution and selectively remove trace pyridine from toluene.
Membranes with fast and selective separation of ions are universally desired in many applications. Here, authors inspired by biological potassium ion channels have constructed an MXene based biomimetic ion channel membrane to achieve efficient separation of ions.
Neutrophil ontogeny in zebrafish may be a continuum or consist of distinct lineages. Here the authors characterise neutrophils derived from rostral blood island and caudal haematopoietic tissue lineages and show differential gene expression and function in steady state and during wound healing.
Truck platooning allows for trucks to travel synchronously in close proximity to improve fuel efficiency. Here, authors evaluate the decarbonization effects of platooning on the vehicle-road system at a large-scale road network level revealing a trade-off between emission reduction and cost rise.
Soil moisture–atmosphere coupling induces non-linear warming via the ‘warmer climate – drier soil’ feedback, which exerts an accelerating effect on global warming and on extremely high temperatures.
Ferromagnetic insulators offer low magnetic damping, and potentially efficient magnetic switching, making them ideal candidates for spin-based information processing. Here, Zheng et al introduce a ferromagnetic insulator spinel, Li0.5Al1.0Fe1.5O4, with low magnetic damping, perpendicular magnetic anisotropy, and no magnetic dead layer.