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One pathway for improving the performance of optoelectronics is the tailoring energy bands of the charge transport layer. Here, Kim et al present a charge transfer complex composed out of nanodomains of MoO3 embedded within an NiO matrix, significantly improving green and blue OLED performance.
Patients with pancreatic cancer have a poor prognosis, more research is required to identify the disease at an earlier stage. Here, the authors use lipid profiles of blood samples and show that they can distinguish patients with pancreatic cancer from healthy controls.
China’s transition path toward carbon neutrality remains uncertain. Here the authors combine Monte Carlo analysis with an energy-environment-economy model to present a probabilistic view of China’s energy transition across 3,000 cases.
Succinylation is a metabolism-associated post-translational protein modification. Here the authors describe changes to the succinylation of proteins in the brain of individuals with Alzheimer’s disease.
The domestic chicken Gallus gallus domesticus is a classic model for the study of folliculogenesis. Here the authors integrate multi-omics analyses characterizing the dynamic transcriptome and chromatin architecture in granulosa cells during chicken folliculogenesis.
Exploiting technologies derived from the optical clocks community, the authors demonstrate a setup for twin-field QKD which extends the coherence times by three orders of magnitude, overcoming the main challenge towards real-world implementation.
The study of the brain’s low-dimensional topology enables the dynamic tracking of changes in neural activity. Here authors show how the reshaping of low-dimensional trajectories of brain activity sustain cognition following focal neural perturbations.
Applications of nanophotonic tweezers have been limited by the low trapping force. Here, the authors present enhanced force generation in a nanophotonic standing-wave array trap by integrating a critically-coupled resonator design and demonstrate common single-molecule experiments.
Ordinary differential equation (ODE) models are widely used to understand multiple processes. Here the authors show how the concept of mini-batch optimization can be transferred from the field of Deep Learning to ODE modelling.
Genome editing methods are limited by the inability to selectively edit repetitive sequences. Here the authors demonstrate precise editing of a repetitive genetic element, a ribosome, while avoiding edits to native sites sharing identical sequence.
Rechargeable Li-I2 battery system is interesting due to high theoretical capacities but the insoluble discharge product at the conventional solid interface leads to poor performances. Here, by using a confined dissolution strategy the authors demonstrate a rechargeable all-solid-state Li-I2 battery with extended cycle life.
Mechanical force is critical for the development and remodeling of bones. Here the authors report that mechanical force regulates the production of the metabolite asymmetric dimethylarginine via regulating the expression of the hydrolytic enzyme dimethylarginine dimethylaminohydrolase 1 in osteoblasts.
UVR8 is a plant photoreceptor that dissociates into monomers after sensing UV. Here, via ultrafast spectroscopy and computational calculations, the authors describe the dynamics of charge separation and charge neutralization in UVR8 and describe how these unzip interactions at the dimer interface.
Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of the catecholamine neurotransmitters and hormones dopamine (DA), adrenaline and noradrenaline. Here, the authors present the cryo-EM structures of full-length human TH in the apo form and bound with DA, as well as the structure of Ser40 phosphorylated TH, and discuss the inhibitory and stabilizing effects of DA on TH and its counteraction by Ser40-phosphorylation.
Developing single atom systems with improved catalytic potential for bio-application has major therapeutic potential. Here, the authors report on the development of a metal single-atom on a carbon dot support confined within mesoporous silica for the development of therapeutic agents.
Though room-temperature phosphorescence (RTP) in organics is advantageous for bioimaging, designing materials that meet lifetime and wavelength emission requirements is challenging. Here, the authors us a guest-host doped strategy to construct RTP materials with ultralong-lifetime, NIR emission.
Accumulation of intermittent solar energy using secondary batteries is an appealing solution for future power sources. Here, the authors propose a device comprising of perovskite solar cells and aqueous zinc metal batteries connected via the sandwich joint electrode method.
Megaripples are sand landforms found in wind-blown environments. A newly identified characteristic signature of the underlying bimodal sand transport process is found in the grain-size distribution on megaripples and could lend insight into transport conditions on Earth and other planetary bodies.
During pyroptosis, gasdermin D (GSDMD) forms plasma membrane pores that initiate cell lysis. Here, the authors develop optogenetically activatable human GSDMD to assess GSDMD pore behavior and show that they are dynamic and can close, which can be a pyroptosis regulatory mechanism.
Unveiling the effect of carbon matrix adjacent to Fe-N towards oxygen reduction reaction is important yet challenging. Here the authors investigate the carbon environment covalent-connected to FeN4 sites on their catalytic activity using models prepared by pyrolysis-free approach.