Browse Articles

The repeated presentation of observed action is hypothesized to result in the reduction in firing rates of mirror neurons in premotor areas of the cortex. In this study, it is shown that monkey premotor area F5 mirror neurons, unlike local field potentials, do not display suppression to repetitive stimuli.

Understanding magnetic materials at the nanoscale is important for the development of novel applications, but has been hampered by a lack of suitable experimental techniques. Here, the use of transmitted electrons permits the determination of atomic site-specific magnetic information.

A variant in the IFITM3gene increases the risk of severe influenza, but homozygosity is rare in Caucasians. The authors show that the variant gene is homozygous in 25% of healthy Chinese people, and 69% of those with severe pandemic influenza, suggesting that this gene influences the epidemiology of influenza in South-East Asia.

The mitochondrial protease CLPP is found in most eukaryotic organisms but its biological role has been unclear. Here Osiewacz and colleagues show that deletion of CLPP extends lifespan of the filamentous fungus Podospora anserina, and that human and fungal CLPP are functionally conserved.

In mature continental rifts, magma intrusion appears to accommodate significant crustal extension. Here, radiometric ages for lavas suggest that this style of focused magmatic accretion and rifting remained stable in the Ethiopian crust for at least ~200 kyr, prior to the onset of true oceanic spreading.

Universal control of the state of qubits on timescales much shorter than the coherence time is necessary for quantum computation. The authors demonstrate electrical control of a charge qubit in quantum dots on the picosecond scale, which is orders of magnitude faster than previously reported.

High-pressure minerals in meteorites reflect the conditions prevailing when they were excavated and launched from their parent bodies. Tissint—a recent Martian meteorite—contains an unusual number of large high-pressure minerals, suggesting excavation from an impact of larger magnitude than for previous Martian samples.

Controlling the interaction between distant quantum dots is important if they are to be used in quantum information devices. Delbecq et al. place two quantum dot circuits in a microwave cavity and show that they interact via cavity photons, even though they are separated by 200 times their own size.

Quantum magnetometry in the solid state is usually affected by short coherence times and control errors that limit the sensitivity. This work demonstrates a continuous-driving scheme based on composite pulses that improves both these shortcomings and can be used in variable sensing environments.

Coral reef health is declining globally and is projected to lead to net loss of reef structure. This study shows that ecological change across the Caribbean has reduced reef growth rates to levels lower than those measured over the last ~8,000 years, threatening the ability of reefs to keep pace with future sea-level rise.

The long-term hydroclimate variability in Amazonia and its influence on biodiversity remain poorly understood. Here, new speleothem oxygen isotope records characterize spatial–temporal changes in precipitation and provide new insights to understanding the west–east contrasting pattern of biodiversity in Amazonia.

One of the advantages that it is hoped quantum computers will have over classical computers is their ability to accurately simulate quantum phenomena. Silveri et al.take a step towards this goal by simulating so-called motional averaging in an artificial atom realized by a superconducting quantum bit.

The rice sheath blight pathogen, Rhizoctonia solani, is an important fungal pathogen that can devastate rice and maize crops. Zheng and colleagues sequence and assemble the R. solani AG1 IA genome—the first to be sequenced from the Rhizoctoniagenus—using Illumina sequencing technology.

DNA replication stress promotes genome instability and cell death. Here Fugger et al.describe how FBH1, via its helicase activity, is required to eliminate cells with excessive DNA replication stress, through the generation of MUS81-induced DNA double-strand breaks.

Damaged mitochondria are eliminated from the cell by a form of autophagy called mitophagy. Here the authors show that during mitophagy, specific proteins are rescued from degradation by evacuation from the mitochondria to the endoplasmic reticulum.

Dendritic cells use protrusive structures called podosomes to probe the extracellular environment. Here the authors reveal how interplay between actin-mediated core growth and myosin-mediated tension regulates podosome protrusion.

Genome-wide variation in the directed evolution of metabolite-overproducing microbes requires high-throughput screening platforms. Yang et al.show that synthetic RNA devices can sense target metabolites, enrich pathway optimisation, and expedite the evolution of metabolite-producing microbes.

Artificially engineered tissues may have many therapeutic applications but complex tissues are hard to create in vitro. Here, Okano and colleagues report the production of functional cardiac tissue sheets with perfusable blood vessels, which increase the thickness and survival of transplanted tissue.

Kidney maintenance and function are essential for a healthy organism. Here Nishinakamura and colleagues show that the phosphatase Dullard suppresses BMP signalling and apoptosis in the mouse kidney and that Dullard is required for the maintenance of functional nephrons after birth.

Free-ranging domestic cats cause wildlife extinctions on islands, but their impact on wildlife in mainland areas is unclear. This study presents an estimate of mortality caused by cats in the United States, suggesting that 1.4–3.7 billion birds and 6.9–20.7 billion mammals are killed annually.