Functionally coupled motions between the voltage-sensing and the phosphatidylinositol phosphatase domains of the sea squirt protein Ci-VSP is mediated by PI(4,5)P2 binding to the intervening linker, shedding light on the function of an unusual voltage-sensing protein.
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Okamura, Y. PI couples voltage to catalysis. Nat Chem Biol 6, 315–316 (2010). https://doi.org/10.1038/nchembio.358
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DOI: https://doi.org/10.1038/nchembio.358
