In This Issue
pvdoi:10.1038/nchembio0606-v
Current issue
June 2006, Volume 2 Number 6 pp283-346
- 1st anniversary highlights
- In This Issue
- Editorial
- Commentary
- Meeting Report
- Elements
- News and Views
- Review
- Brief Communication
- Letters
- Articles
- Erratum
- Corrigendum
- About the cover
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1st anniversary highlights
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In This Issue
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Commentary
Making carbon-nitrogen bonds in biological and chemical synthesis
pp284 - 287Ryan Hili and Andrei K Yudin
doi:10.1038/nchembio0606-284
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Meeting Report
A century at the chemistry-biology interface
pp288 - 292Jennifer J Kohler
doi:10.1038/nchembio0606-288
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News and Views
Snapshots of three intermediates at the active site of pyruvate oxidase
pp294 - 295Perry A Frey
doi:10.1038/nchembio0606-294
See also: Letter by Wille et al.
Signalomic signatures enlighten drug profiling
pp295 - 296Robert T Abraham
doi:10.1038/nchembio0606-295
See also: Article by MacDonald et al.
Nucleation of huntingtin aggregation in cells
pp297 - 298Ronald Wetzel
doi:10.1038/nchembio0606-297
See also: Letter by Colby et al.
Wanting contact: how to pick up a channel
pp298 - 299Daniel L Minor, Jr
doi:10.1038/nchembio0606-298
See also: Letter by Holden et al.
Chemical knockout of C-reactive protein in cardiovascular disease
pp300 - 301Jay W Heinecke
doi:10.1038/nchembio0606-300
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Review
Modular approaches to expanding the functions of living matter
pp304 - 311Jason W Chin
Published online:
18 May 2006 | doi:10.1038/nchembio789
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Brief Communication
Site-specific PEGylation of native disulfide bonds in therapeutic proteins
pp312 - 313Sunil Shaunak, Antony Godwin, Ji-Won Choi, Sibu Balan, Elisa Pedone, Damotharan Vijayarangam, Sibylle Heidelberger, Ian Teo, Mire Zloh and Steve Brocchini
Published online:
23 April 2006 | doi:10.1038/nchembio786
Abstract | Full Text | PDF (168K) | Supplementary information
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Letters
Direct transfer of membrane proteins from bacteria to planar bilayers for rapid screening by single-channel recording
pp314 - 318Matthew A Holden, Lakmal Jayasinghe, Oliver Daltrop, Amy Mason and Hagan Bayley
Published online:
07 May 2006 | doi:10.1038/nchembio793
First paragraph | Full Text | PDF (404K) | Supplementary information
Stochastic kinetics of intracellular huntingtin aggregate formation
pp319 - 323David W Colby, John P Cassady, Grace C Lin, Vernon M Ingram and K Dane Wittrup
Published online:
14 May 2006 | doi:10.1038/nchembio792
First paragraph | Full Text | PDF (230K) | Supplementary information
The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography
pp324 - 328Georg Wille, Danilo Meyer, Andrea Steinmetz, Erik Hinze, Ralph Golbik and Kai Tittmann
Published online:
07 May 2006 | doi:10.1038/nchembio788
First paragraph | Full Text | PDF (516K) | Supplementary information
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Articles
Identifying off-target effects and hidden phenotypes of drugs in human cells
pp329 - 337Marnie L MacDonald, Jane Lamerdin, Stephen Owens, Brigitte H Keon, Graham K Bilter, Zhidi Shang, Zhengping Huang, Helen Yu, Jennifer Dias, Tomoe Minami, Stephen W Michnick and John K Westwick
Published online:
07 May 2006 | doi:10.1038/nchembio790
Abstract | Full Text | PDF (693K) | Supplementary information
The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans
pp338 - 345David Kokel, Yehua Li, Jun Qin and Ding Xue
Published online:
14 May 2006 | doi:10.1038/nchembio791
Abstract | Full Text | PDF (305K) | Supplementary information
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Erratum
Top of pageCorrigendum: Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate
p346
Corrigendum
Corrigendum: Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate 
-synuclein fibrilization
p346Daryl A Bosco, Douglas M Fowler, Qinghai Zhang, Jorge Nieva, Evan T Powers, Paul Wentworth, Jr, Richard A Lerner and Jeffery W Kelly
doi:10.1038/nchembio0606-346b
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