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Asymmetric catalysis

A radical revolution in synthesis

A newly designed thiol catalyst for radical cyclization reactions is the result of a long and storied battle to control the reactivity of carbon-centred radicals.

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Figure 1: Enantioselective reaction of a carbon-centred radical.
Figure 2

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Correspondence to Andrew F. Parsons.

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Parsons, A. A radical revolution in synthesis. Nature Chem 6, 659–661 (2014). https://doi.org/10.1038/nchem.2012

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