Obtaining detailed structural information about the interactions between amyloid-forming proteins and inhibitors can be extremely difficult. Two-dimensional infrared spectroscopy has now risen to this challenge to show the mapping of protein–protein contact sites in real time.
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Cho, M. Mapping protein–protein contacts. Nature Chem 4, 339–341 (2012). https://doi.org/10.1038/nchem.1336
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DOI: https://doi.org/10.1038/nchem.1336
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