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Letter
Nature Cell Biology 10, 1440–1446 (1 December 2008) | doi:10.1038/ncb1803
Regulation of the Drosophila apoptosome through feedback inhibition
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Abstract
Apoptosis is induced by caspases, which are members of the cysteine protease family. Caspases are synthesized as inactive zymogens and initiator caspases first gain activity by associating with an oligomeric complex of their adaptor proteins, such as the apoptosome.
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