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Nature Biotechnology 27, 847–850 (1 September 2009) | doi:10.1038/nbt.1561

Single-molecule sequencing of an individual human genome

Dmitry Pushkarev , Norma F Neff & Stephen R Quake

Recent advances in high-throughput DNA sequencing technologies have enabled order-of-magnitude improvements in both cost and throughput. Here we report the use of single-molecule methods to sequence an individual human genome.