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Volume 25 Issue 9, September 2007

Bantscheff et al. use mass spectrometry to identify and quantify proteins trapped by kinobeads in the presence of increasing concentrations of a kinase inhibitor, such as imatinib (shown). Simultaneously profiling the binding of hundreds of potential cellular targets to a drug should facilitate prediction of its in vivo efficacy and safety (p 1035). Credit: Ken Eward, ©BioGrafx.

Volume 25 Issue 9

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Editorial

  • More definitive answers about the death of a woman in an adeno-associated virus (AAV) gene therapy trial for arthritis must await a meeting of the Recombinant DNA Advisory Committee (RAC) later this month.

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  • To what extent did the French government's failure to publicly disclose the exact location of field trials contribute to the suicide of a farmer hounded by anti-GM activists?

    Editorial

  • A meeting earlier this year in Toronto offered a unique forum for showcasing biotech firms from emerging economies.

    Editorial
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News

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News in Brief

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Data Page

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News Feature

  • Recombinant technology has not yet taken root in ornamental plant breeding, but if some early genetically modified products succeed in the marketplace, might this change?

    • Carol Potera
    News Feature
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Correspondence

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Book Review

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Feature

  • An unprecedented study claiming that transgenic soybeans compromise the fertility of rats and the survival and growth of their offspring has garnered widespread media and political attention but remains unpublished in the peer-reviewed literature. Here, an account of the work from the principal investigator, Irina Ermakova, is appended with comments from researchers in the field.

    • Andrew Marshall
    Feature
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Patents

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News & Views

  • Cardiomyocytes derived from human embryonic stem cells prove beneficial in an animal model of myocardial infarction.

    • Michael Rubart
    • Loren J Field
    News & Views

  • Cellular targets of kinase inhibitors are identified by mass spectrometric analysis of binding to “kinobeads.”

    • Forest M White
    News & Views

  • microRNA expression has been profiled in a broad range of cell types.

    • Lee P Lim
    • Peter S Linsley
    News & Views
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Analysis

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