About the cover
July 2007 Volume 25 No 7
A model of two zinc-finger nucleases bound to DNA overlaid on an image of a metaphase chromosome spread. The side chains shown are key to the dimer interface of the cleavage domains, according to Miller et al. Two papers in this issue redesign the dimer interface to reduce off-target DNA cleavage. (pp 778 and 786) Credit: Jeffrey C. Miller
