Figure 3 - Antiviral mechanisms mediated by antibody Fc.


From the following article

The growth and potential of human antiviral monoclonal antibody therapeutics

Wayne A Marasco & Jianhua Sui

Nature Biotechnology 25, 1421 - 1434 (2007) Published online: 7 December 2007

doi:10.1038/nbt1363

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Antibody-dependent cell-mediated cytotoxicity (ADCC) is shown on the left. Antibody opsonization and activation of the complement leads to antibody-dependent, complement-mediated virolysis, phagocytosis directed against free virions or infected cells (only the free virus is shown) are shown on the right. NK, natural killer.

Katie Ris-Vicari

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