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Nature Biotechnology 24, 713 - 717 (2006)
Published online: 4 June 2006; | doi:10.1038/nbt1213

Herbicide-resistance conferred by expression of a catalytic antibody in Arabidopsis thaliana

Yael Weiss, Avidor Shulman, Irina Ben Shir, Ehud Keinan & Shmuel Wolf

 
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Figure 1. Herbicidal activity of keto-cartamates.
(a) Antibody-catalyzed fragmentation mechanism of keto-carbamate 9 via a Schiff-base intermediate. (b) Keto-carbamate herbicide candidates, which were tested as substrates of 38C2 and general herbicides. The structure of each compound is presented together with its Michaelis-Menten kinetic parameters. (c) Herbicidal activity of compound 9 and propham with potato (cv. Desiree) shoots that were grown in the presence of 1 mM of each herbicide. (d) Herbicidal activities of compound 9 and propham with respect to germination of A. thaliana (ecotype Columbia) seeds. Four concentrations were examined for each compound.

 
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