Access

Research

Nature Biotechnology 24, 435–436 (1 April 2006) | doi:10.1038/nbt1198

Generation of cloned transgenic pigs rich in omega-3 fatty acids

Liangxue Lai , Jing X Kang , Rongfeng Li , Jingdong Wang , William T Witt , Hwan Yul Yong , Yanhong Hao , David M Wax , Clifton N Murphy , August Rieke , Melissa Samuel , Michael L Linville , Scott W Korte , Rhobert W Evans , Thomas E Starzl , Randall S Prather & Yifan Dai

Meat products are generally low in omega-3 (n-3) fatty acids, which are beneficial to human health. We describe the generation of cloned pigs that express a humanized Caenorhabditis elegans gene, fat-1, encoding an n-3 fatty acid desaturase.