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| Editorial | Top |
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In it for the long haul p115
doi:10.1038/nbt0206-115
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News |
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China offers alternative gateway for experimental drugs pp117 - 118
Hepeng Jia & Jim Kling
doi:10.1038/nbt0206-117
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Amgen becomes a stronger cancer player
p119
Jim Kling
doi:10.1038/nbt0206-119
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Industry warily eyes new Medicare drug plan
p120
Brian Vastag
doi:10.1038/nbt0206-120
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Nanomedicine lacks recognition in Europe
p121
Nuala Moran
doi:10.1038/nbt0206-121
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In Brief |
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News In Brief
pp123 - 124
doi:10.1038/nbt0206-123
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Profile: Einer Elhauge
p125
Mark Ratner
doi:10.1038/nbt0206-125
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| Data Page |
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2005: Biotech partners up p126
Stacy Lawrence
doi:10.1038/nbt0206-126
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News Feature |
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The second wave in kinase cancer drugs
pp127 - 130
Ken Garber
doi:10.1038/nbt0206-127
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| Bioentrepreneur | Top |
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| Bioenews |
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Biotech entrepreneur, educate thyself! pp131 - 132
Emily Waltz
Published online: 15 December 2005
| doi:10.1038/bioent896
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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| Building a business |
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Keeping it real with investors pp133 - 135
Michelle Dipp, Christoph Westphal, Chad Mirkin, James Baker, Tim Harper
& Charles Harris
Published online: 24 January 2006
| doi:10.1038/bioent899
Reprinted with some modification from the Bioentrepreneur web portal (http://www.nature.com/bioent)
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| Opinion and Comment | Top |
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| Correspondence |
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Depicting signaling cascades pp137 - 138
Michael L. Blinov, Jin Yang, James R. Faeder
& William S. Hlavacek
doi:10.1038/nbt0206-137
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Reply to Depicting signaling cascades p138
doi:10.1038/nbt0206-138
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A DNA flu vaccine in practice p139
Peter Dunnill
doi:10.1038/nbt0206-139a
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Sequencing thoroughbreds p139
George Church, Jay Shendure
& Greg Porreca
doi:10.1038/nbt0206-139b
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| Commentary |
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South Korean policy failure and the Hwang debacle pp141 - 143
Herbert Gottweis
& Robert Triendl
doi:10.1038/nbt0206-141
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| Investor's Lab |
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When your stock takes a nosedive p144
Tom Jacobs
doi:10.1038/nbt0206-144
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| Features | Top |
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A turbulent year at the agency pp145 - 151
Mark Ratner
doi:10.1038/nbt0206-145
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| Patents |
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The importance of getting inventorship right pp153 - 154
Diana Sheiness
& Karen Canady
doi:10.1038/nbt0206-153
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Recent patent applications in angiogenesis research p155
doi:10.1038/nbt0206-155
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| News and Views | Top |
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The next chapter in reverse vaccinology pp157 - 158
James M Musser
doi:10.1038/nbt0206-157
Abstract | Full text | PDF
(118K)
See also: Research by Rodríguez-Ortega et al. |
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AAV does the shuffle pp158 - 160
Aravind Asokan
& R Jude Samulski
doi:10.1038/nbt0206-158
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(133K)
See also: Research by Maheshri et al. |
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The medium is the message pp160 - 161
Harry Moore
doi:10.1038/nbt0206-160
Abstract | Full text | PDF
(144K)
See also: Research by Ludwig et al. |
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Plants tackle explosive contamination pp161 - 163
Richard B Meagher
doi:10.1038/nbt0206-161
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(942K)
See also: Research by Rylott et al. |
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Designer combination therapy for cancer pp163 - 164
David Lane
doi:10.1038/nbt0206-163
Abstract | Full text | PDF
(812K)
See also: Research by Rubinfeld et al. |
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Research Highlights p165
doi:10.1038/nbt0206-165
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| Computational Biology | Top |
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| Review |
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Statistical practice in high-throughput screening data analysis pp167 - 175
Nathalie Malo, James A Hanley, Sonia Cerquozzi, Jerry Pelletier
& Robert Nadon
Published online: 07 February 2006 | doi:10.1038/nbt1186
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| Research | Top |
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| Perspective |
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Screening for peptide drugs from the natural repertoire of biodiverse protein folds pp177 - 183
Paul M Watt
Published online: 07 February 2006 | doi:10.1038/nbt1190
Abstract | Full text | PDF
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| Brief Communications |
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Derivation of human embryonic stem cells in defined conditions pp185 - 187
Tenneille E Ludwig, Mark E Levenstein, Jeffrey M Jones, W Travis Berggren, Erika R Mitchen, Jennifer L Frane, Leann J Crandall, Christine A Daigh, Kevin R Conard, Marian S Piekarczyk, Rachel A Llanas
& James A Thomson
Published online: 01 January 2006 | doi:10.1038/nbt1177
Abstract | Full text | PDF
(203K)
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See also: News and Views by Moore |
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Engineered membrane superchannel improves bioremediation potential of dioxin-degrading bacteria pp188 - 189
Yuji Aso, Yukiko Miyamoto, Karen Mine Harada, Keiko Momma, Shigeyuki Kawai, Wataru Hashimoto, Bunzo Mikami
& Kousaku Murata
Published online: 15 January 2006 | doi:10.1038/nbt1181
Abstract | Full text | PDF
(138K)
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| Articles |
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Characterization and identification of vaccine candidate proteins through analysis of the group A Streptococcus surface proteome pp191 - 197
Manuel J Rodríguez-Ortega, Nathalie Norais, Giuliano Bensi, Sabrina Liberatori, Sabrina Capo, Marirosa Mora, Maria Scarselli, Francesco Doro, Germano Ferrari, Ignazio Garaguso, Tiziana Maggi, Anita Neumann, Alessia Covre, John L Telford
& Guido Grandi
Published online: 15 January 2006 | doi:10.1038/nbt1179
Abstract | Full text | PDF
(404K)
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See also: News and Views by Musser |
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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors pp198 - 204
Narendra Maheshri, James T Koerber, Brian K Kaspar
& David V Schaffer
Published online: 22 January 2006 | doi:10.1038/nbt1182
Abstract | Full text | PDF
(343K)
| Supplementary Information
See also: News and Views by Asokan & Samulski |
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| Letters |
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Identification and immunotherapeutic targeting of antigens induced by chemotherapy pp205 - 209
Bonnee Rubinfeld, Archana Upadhyay, Suzanna L Clark, Sharon E Fong, Victoria Smith, Hartmut Koeppen, Sarajane Ross
& Paul Polakis
Published online: 29 January 2006 | doi:10.1038/nbt1185
Abstract | Full text | PDF
(374K)
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See also: News and Views by Lane |
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Optimization of humanized IgGs in glycoengineered Pichia pastoris pp210 - 215
Huijuan Li, Natarajan Sethuraman, Terrance A Stadheim, Dongxing Zha, Bianka Prinz, Nicole Ballew, Piotr Bobrowicz, Byung-Kwon Choi, W James Cook, Michael Cukan, Nga Rewa Houston-Cummings, Robert Davidson, Bing Gong, Stephen R Hamilton, Jack P Hoopes, Youwei Jiang, Nam Kim, Renee Mansfield, Juergen H Nett, Sandra Rios, Rendall Strawbridge, Stefan Wildt
& Tillman U Gerngross
Published online: 22 January 2006 | doi:10.1038/nbt1178
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(314K)
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An explosive-degrading cytochrome P450 activity and its targeted application for the phytoremediation of RDX pp216 - 219
Elizabeth L Rylott, Rosamond G Jackson, James Edwards, Grant L Womack, Helena MB Seth-Smith, Deborah A Rathbone, Stuart E Strand
& Neil C Bruce
Published online: 22 January 2006 | doi:10.1038/nbt1184
Abstract | Full text | PDF
(263K)
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See also: News and Views by Meagher |
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| Errata | Top |
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Erratum: Banking on cord blood from India p220
Jayaraman Killugudi
doi:10.1038/nbt0206-220a
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Erratum: Korean biotechs seize opportunity to list on public markets p220
Sabine Louët
doi:10.1038/nbt0206-220b
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Erratum: Pessimistic response to FDA leadership change p220
Jim Kling
doi:10.1038/nbt0206-220c
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Erratum: China's biotech experiments p220
Hepeng Jia
doi:10.1038/nbt0206-220d
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| Corrigendum | Top |
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Corrigendum: Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains p220
Joshua Silverman, Qiang Lu, Alice Bakker, Wayne To, Amy Duguay, Ben M Alba, Richard Smith, Alberto Rivas, Peng Li, Hon Le, Erik Whitehorn, Kevin W Moore, Candace Swimmer, Victor Perlroth, Martin Vogt, Joost Kolkman
& Willem Pim C Stemmer
doi:10.1038/nbt0206-220e
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| Naturejobs | Top |
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| Careers and Recruitment |
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Chinese biotech: the need for innovation and higher standards pp221 - 222
Grace H W Wong
doi:10.1038/nbt0206-221
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| People |
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People p224
doi:10.1038/nbt0206-224
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