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AAV does the shuffle

Nature Biotechnology volume 24, pages 158–160 (2006)Cite this article

Directed evolution of adeno-associated virus (AAV) yields mutant vectors that can evade neutralizing antibodies.

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Figure 1: Generation of an AAV library by a recombination technique analogous to DNA shuffling followed by directed evolution.

Bob Crimi

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Authors and Affiliations

  1. the Gene Therapy Center, 7113 Thurston Building, University of North Carolina at Chapel Hill, Chapel Hill, 27599, North Carolina, USA

    Aravind Asokan & R Jude Samulski

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  1. Aravind Asokan
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  2. R Jude Samulski
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Asokan, A., Samulski, R. AAV does the shuffle. Nat Biotechnol 24, 158–160 (2006). https://doi.org/10.1038/nbt0206-158

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