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Nature Biotechnology 22, 1559–1566 (1 December 2004) | doi:10.1038/nbt1033

RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy

Robert S Allen , Anthony G Millgate , Julie A Chitty , Jennifer Thisleton , James A C Miller , Anthony J Fist , Wayne L Gerlach & Philip J Larkin