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Colorectal cancer

Vol. 521 No. 7551_supp ppS1-S46

In this Supplement
Colorectal cancer is the world’s fourth most deadly cancer, killing almost 700,000 people every year. And it is expected to become more common as more people adopt Western diets and lifestyles, which are implicated as risk factors. But research into screening, prevention and treatments is helping to fight the disease.

Cover Art: Mario Wagner

Outlook

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Colorectal cancer
- Herb Brody
Nature 521, S1 (13 May 2015)
A disease of growth
- David Holmes
Nature 521, S2–S3 (13 May 2015)
Screening: Early alert
- Cassandra Willyard
Nature 521, S4–S5 (13 May 2015)
Prevention: Tending the gut
- Lauren Gravitz
Nature 521, S6–S8 (13 May 2015)
Q&A: Victor Velculescu
Out for blood
- Eric Bender
Nature 521, S9 (13 May 2015)
Microbiome: Microbial mystery
- Sarah DeWeerdt
Nature 521, S10–S11 (13 May 2015)
Drug development: Mix and match
- Megan Scudellari
Nature 521, S12–S14 (13 May 2015)
Q&A: Hans Clevers
Banking on organoids
- Eric Bender
Nature 521, S15 (13 May 2015)
Colorectal cancer: 5 big questions
- Shraddha Chakradhar
Nature 521, S16 (13 May 2015)

Animation

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Colorectal cancer: A disease of development

Colorectal cancer is a disease of development. Across the globe, as economies grow, so too does the incidence of colorectal cancer. Lifestyle changes are to blame, and in this Nature Video we see how increases in colorectal cancer are affecting many countries around the world, and what this could mean in the future to a world that is still developing.

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Host–microbe interactions and spatial variation of cancer in the gut
- Fergus Shanahan
- Paul W. O'Toole
Nature Reviews Cancer (26 June 2014 )
Prospective study of EGFR intron 1 (CA)_n repeats variants as predictors of benefit from cetuximab and irinotecan in chemo-refractory metastatic colorectal cancer (mCRC) patients
- F Loupakis
- C Antoniotti
- C Cremolini
- W Zhang
- D Yang
- T Wakatsuki
- P Bohanes
- M Schirripa
- L Salvatore
- G Masi
- V Ricci
- F Graziano
- A Ruzzo
- L Benhaim
- F Marmorino
- Y Ning
- R El-Khoueiry
- A Falcone
- H-J Lenz
The Pharmacogenomics Journal 14, 322–327 (11 February 2014)
Colonoscopy: Quality Indicators
- Joseph C Anderson
- Lynn F Butterly
Clinical and Translational Gastroenterology 6, e77 (26 February 2015)
Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids
- Mami Matano
- Shoichi Date
- Mariko Shimokawa
- Ai Takano
- Masayuki Fujii
- Yuki Ohta
- Toshiaki Watanabe
- Takanori Kanai
- Toshiro Sato
Nature Medicine 21, 256–262 (23 February 2015)
Television watching and risk of colorectal adenoma
- Y Cao
- N N Keum
- A T Chan
- C S Fuchs
- K Wu
- E L Giovannucci
British Journal of Cancer 112, 934–942 (15 January 2015)

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For more on colorectal cancer from nature.com, see:
nature.com/subjects/colorectal-cancer

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Supplement

Colorectal cancer

In this Supplement

Outlook

Colorectal cancer

A disease of growth

Screening: Early alert

Prevention: Tending the gut

Q&A: Victor Velculescu
Out for blood

Microbiome: Microbial mystery

Drug development: Mix and match

Q&A: Hans Clevers
Banking on organoids

Colorectal cancer: 5 big questions

Animation

Colorectal cancer: A disease of development

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Related articles

Host–microbe interactions and spatial variation of cancer in the gut

Prospective study of EGFR intron 1 (CA)_n repeats variants as predictors of benefit from cetuximab and irinotecan in chemo-refractory metastatic colorectal cancer (mCRC) patients

Colonoscopy: Quality Indicators

Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids

Television watching and risk of colorectal adenoma

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