Controversial insecticides linked to wild bee declines Mark Bretherton/Alamy Stock Photo Evidence against neonicotinoid chemicals mounts ahead of EU review. A dip in the populations of wild bees across the English countryside over nine years coincided with the use of chemicals called neonicotinoids on the crops in which the bees …
LetterDiverse activation pathways in class A GPCRs converge near the G-protein-coupling region A. J. Venkatakrishnan Xavier Deupi Guillaume Lebon Franziska M. Heydenreich Tilman Flock Tamara Miljus Santhanam Balaji Michel Bouvier Dmitry B. Veprintsev Christopher G. Tate Gebhard F. X. Schertler M. Madan Babu Computational biology and bioinformatics G protein-coupled receptors
ArticleSEDS proteins are a widespread family of bacterial cell wall polymerases Alexander J. Meeske Eammon P. Riley William P. Robins Tsuyoshi Uehara John J. Mekalanos Daniel Kahne Suzanne Walker Andrew C. Kruse Thomas G. Bernhardt David Z. Rudner Bacterial physiology Bacteriology Cellular microbiology
LetterThe long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan Jonathan J. Kotzin Sean P. Spencer Sam J. McCright Dinesh B. Uthaya Kumar, Magalie A. Collet Walter K. Mowel Ellen N. Elliott Asli Uyar Michelle A. Makiya Margaret C. Dunagin Christian C. D. Harman Anthony T. Virtue Stella Zhu Will Bailis Judith Stein Cynthia Hughes Arjun Raj E. John Wherry Loyal A. Goff Amy D. Klion John L. Rinn Adam Williams Richard A. Flavell Jorge Henao-Mejia Gene regulation in immune cells Immune cell death
LetterCompression and ablation of the photo-irradiated molecular cloud the Orion Bar Javier R. Goicoechea Jérôme Pety Sara Cuadrado José Cernicharo Edwige Chapillon Asunción Fuente Maryvonne Gerin Christine Joblin Nuria Marcelino Paolo Pilleri Atomic and molecular physics Interstellar medium Space physics
LetterA progressively wetter climate in southern East Africa over the past 1.3 million years T. C. Johnson J. P. Werne E. T. Brown A. Abbott M. Berke B. A. Steinman J. Halbur S. Contreras S. Grosshuesch A. Deino C. A. Scholz R. P. Lyons S. Schouten J. S. Sinninghe Damsté Limnology Palaeoclimate
LetterA human neurodevelopmental model for Williams syndrome Thanathom Chailangkarn Cleber A. Trujillo Beatriz C. Freitas Branka Hrvoj-Mihic Roberto H. Herai Diana X. Yu Timothy T. Brown Maria C. Marchetto Cedric Bardy Lauren McHenry Lisa Stefanacci Anna Järvinen Yvonne M. Searcy Michelle DeWitt Wenny Wong Philip Lai M. Colin Ard Kari L. Hanson Sarah Romero Bob Jacobs Anders M. Dale Li Dai Julie R. Korenberg Fred H. Gage Ursula Bellugi Eric Halgren Katerina Semendeferi Alysson R. Muotri Cellular neuroscience Neurodevelopmental disorders Reprogramming
ArticleCapturing a substrate in an activated RING E3/E2–SUMO complex Frederick C. Streich Jr Christopher D. Lima DNA damage and repair Enzyme mechanisms Ubiquitins X-ray crystallography
ArticleMolecular basis of APC/C regulation by the spindle assembly checkpoint Claudio Alfieri Leifu Chang Ziguo Zhang Jing Yang Sarah Maslen Mark Skehel David Barford Checkpoints Cryoelectron microscopy
LetterPancreatic stellate cells support tumour metabolism through autophagic alanine secretion Cristovão M. Sousa Douglas E. Biancur Xiaoxu Wang Christopher J. Halbrook Mara H. Sherman Li Zhang Daniel Kremer Rosa F. Hwang Agnes K. Witkiewicz Haoqiang Ying John M. Asara Ronald M. Evans Lewis C. Cantley Costas A. Lyssiotis Alec C. Kimmelman Cancer metabolism Cancer microenvironment
ArticlePostglacial viability and colonization in North America’s ice-free corridor Mikkel W. Pedersen Anthony Ruter Charles Schweger Harvey Friebe Richard A. Staff Kristian K. Kjeldsen Marie L. Z. Mendoza Alwynne B. Beaudoin Cynthia Zutter Nicolaj K. Larsen Ben A. Potter Rasmus Nielsen Rebecca A. Rainville Ludovic Orlando David J. Meltzer Kurt H. Kjær Eske Willerslev Environmental impact Molecular biology Palaeoecology
LetterNatural courtship song variation caused by an intronic retroelement in an ion channel gene Yun Ding Augusto Berrocal Tomoko Morita Kit D. Longden David L. Stern Behavioural genetics Evolutionary genetics
LetterStructure of mammalian respiratory complex I Jiapeng Zhu Kutti R. Vinothkumar Judy Hirst Cryoelectron microscopy Mitochondrial proteins Oxidoreductases
LetterHIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis David A. Jacques William A. McEwan Laura Hilditch Amanda J. Price Greg J. Towers Leo C. James Retrovirus Viral proteins X-ray crystallography
News and ViewsCancer metabolism: Friendly neighbours feed tumour cells Jurre J. Kamphorst Eyal Gottlieb Cancer
News and ViewsStructural biology: Catalytic spliceosome captured Brian Kosmyna Charles C. Query Biochemistry Molecular biology Structural biology
Beyond CRISPR: A guide to the many other ways to edit a genome The popular technique has limitations that have sparked searches for alternatives. image credit: Laguna Design/SPL 11 August 2016
Nature Podcast This week, the migration route of the first Americans, the bandwidth crisis, clever conductors, and the next CRISPR. 11 August 2016
FeatureResearch protocols: A forest of hypotheses Falling in love with a single theory can cut off fruitful avenues of enquiry. Here's how to keep you…
FeatureConference presentations: Lead the poster parade An eye-catching presentation can attract potential collaborators — and even a cash prize.