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From the following article:

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

Antoine R. Adamantidis, Feng Zhang, Alexander M. Aravanis, Karl Deisseroth & Luis de Lecea

Nature 450, 420-424(15 November 2007)

doi:10.1038/nature06310

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Genetically targeted cell-type-specific optical control of Hcrt neurons using ChR2.

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Figure 2

Integrated in vivo optical and physiological system for control of the lateral hypothalamus in the setting of behavioural analysis.

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Figure 3

In vivo photostimulation of Hcrt neurons drives sleep-to-wake transitions.

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Figure 4

Behavioural transitions induced by photostimulation are mediated by Hcrt.

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