Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 449, 811-818 (18 October 2007) | doi:10.1038/nature06245; Published online 17 October 2007
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Postdoctoral Fellow - Computational Genomics - Team 78 – Ref: 80464
- Wellcome Trust Sanger Institute
- Hinxton, Cambridgeshire CB10 1, UK
Leadership Fellowships
- University of Oxford
- Oxford United Kingdom
Review Article An ecological and evolutionary perspective on human–microbe mutualism and disease
Les Dethlefsen1, Margaret McFall-Ngai2 & David A. Relman1,3,4
Abstract
The microbial communities of humans are characteristic and complex mixtures of microorganisms that have co-evolved with their human hosts. The species that make up these communities vary between hosts as a result of restricted migration of microorganisms between hosts and strong ecological interactions within hosts, as well as host variability in terms of diet, genotype and colonization history. The shared evolutionary fate of humans and their symbiotic bacteria has selected for mutualistic interactions that are essential for human health, and ecological or genetic changes that uncouple this shared fate can result in disease. In this way, looking to ecological and evolutionary principles might provide new strategies for restoring and maintaining human health.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Human and microbe: united we standNature Medicine News and Views (01 Jul 2006)
Getting to the core of the gut microbiomeNature Biotechnology News and Views (01 Apr 2009)
See all 3 matches for News And Views