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Crystallography

Crystallographic evidence for deviating C3b structure (Reply)

Nature volume 448, pages E2–E3 (2007)Cite this article

Abstract

We concur with Janssen et al.1 that the structure of C3b that we reported (Protein Data Bank entry 2HR0)2 differs from the other two (2ICF (ref. 3) and 2I07 (ref. 4) in the conformation of the CUB and TED domains. The deviation of 2HR0 from 2I07 is probably relevant physiologically, considering that CUB eventually unfolds.

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Figure 1: Crystal lattice and normalized B factors.

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References

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Authors and Affiliations

  1. Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham, Birmingham, 35294, Alabama, USA

    A. Abdul Ajees, Krishnasamy Gunasekaran, Sthanam V. L. Narayana & H. M. Krishna Murthy

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  1. A. Abdul Ajees
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  2. Krishnasamy Gunasekaran
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  3. Sthanam V. L. Narayana
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  4. H. M. Krishna Murthy
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Correspondence to Krishnasamy Gunasekaran.

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Ajees, A., Gunasekaran, K., Narayana, S. et al. Crystallographic evidence for deviating C3b structure (Reply). Nature 448, E2–E3 (2007). https://doi.org/10.1038/nature06103

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