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Nature 444, 288-294 (16 November 2006) | doi:10.1038/nature05401; Published online 15 November 2006
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Review Article The receptors and cells for mammalian taste
Jayaram Chandrashekar1, Mark A. Hoon2, Nicholas J. P. Ryba2 & Charles S. Zuker1
Abstract
The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to what was generally believed, it is now clear that distinct cell types expressing unique receptors are tuned to detect each of the five basic tastes: sweet, sour, bitter, salty and umami. Importantly, receptor cells for each taste quality function as dedicated sensors wired to elicit stereotypic responses.
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