Editorials

Priorities in astronomy p371

US astronomers are being forced to revisit their widely admired system for ranking large projects.

doi:10.1038/443371a

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A German academy p371

In seeking to build a credible national academy from scratch, Germany faces a tough challenge.

doi:10.1038/443371b

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Reforms on drug safety p372

Critics of the US Food and Drug Administration have a valid point.

doi:10.1038/443372a

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Research Highlights

Research highlights p374

doi:10.1038/443374a

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News

Stem cells derived from 'dead' human embryo p376

IVF cast-offs could provide 'ethical' source of eggs.

Helen Pearson and Alison Abbott

doi:10.1038/443376a

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Superconductivity research is down but not out p376

Absolute zero: survey suggests no papers for field after 2015.

Katharine Sanderson

doi:10.1038/443376b

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Is US hurricane report being quashed? p378

Some NOAA scientists say political appointees blocked climate-change message.

Jim Giles

doi:10.1038/443378a

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Snapshot: Face facts p379

A blow for Mars conspiracy theorists.

Jenny Hogan

doi:10.1038/443379a

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Statistical flaw trips up study of bad stats p379

Experts disagree over reanalysis of original data.

Jim Giles

doi:10.1038/443379b

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Sidelines p380

doi:10.1038/443380a

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Bad Boys question received wisdom on HIV p380

Cleveland gang tackle relation of viral load to AIDS.

Erika Check

doi:10.1038/443380b

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Mouse brain map is complete p380

Gene expression database goes online

David Brill

doi:10.1038/443380c

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'Big science' protein project under fire p382

Critics question results as Protein 3000 winds down

David Cyranoski

doi:10.1038/443382a

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News in brief p383

doi:10.1038/443383a

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Correction p383

doi:10.1038/443383b

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Business

Turbulent times p385

The bid by Airbus to challenge the Boeing 747's dominance of the market faces an aerodynamic obstacle. Ned Stafford reports.

Ned Stafford

doi:10.1038/443385a

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News Features

Decadal surveys: Wishing for the stars p386

US astronomers are renowned for getting together and choosing their projects as a group. But just as these tactics are catching on in other fields, some say the astronomy process is grinding to a halt. Geoff Brumfiel investigates.

doi:10.1038/443386a

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Hagia Sophia: Shaken, not stirred p390

Hagia Sophia has stood four-square in Istanbul for more than 1,500 years. Virginia Hughes finds out how this venerable building has resisted the area's numerous earthquakes.

doi:10.1038/443390a

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Science journalism: Fighting a reporting battle p392

Science journalists in the developing world face unique stumbling blocks, even as some of the biggest science stories unfold around them. Mike Shanahan reports.

doi:10.1038/443392a

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Correspondence

Hungary's 'reforms' are threatening basic science p394

Zsuzsanna Izsvák, Zoltán Ivics and Lajos Mátés

doi:10.1038/443394a

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Challenge of choosing right level of microarray detail p394

Ron Edgar

doi:10.1038/443394b

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Funders with money to spare could just pay more p394

Shantenu Jha

doi:10.1038/443394c

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Piltdown wasn't cricket but does the hobbit ring true? p394

Simon L. Goodman

doi:10.1038/443394d

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Books and Arts

The making of the modern world p395

The end of the Second World War heralded a revolution in the use of technology in the West.

Nasir Tyabji reviews Transforming the Twentieth Century: Technical Innovations and their Consequences by Vaclav Smil

doi:10.1038/443395a

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Science uncut p396

Lee M. Silver reviews Sex, Drugs and DNA: Science's Taboos Confronted by Michael Stebbins

doi:10.1038/443396a

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Border crossings p397

doi:10.1038/443397a

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The moral element p397

Prashanth Ak reviews Against Bioethics by Jonathan Baron

doi:10.1038/443397b

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In Retrospect: Intellect and intuition p398

Gautam R Desiraju reviews An Idealist View of Life by Sarvepalli Radhakrishnan

doi:10.1038/443398a

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News and Views

Ecology: A pitcher of things to come p399

Big conclusions can be drawn from the tiny ecosystems that flourish in carnivorous pitcher plants. Manipulating habitat size and predator abundance reveals which is more important to ecosystem dynamics.

Jonathan B Shurin

doi:10.1038/443399a

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Chemistry: Hydrogen at the flick of a switch p400

Before hydrogen can be used as a transportation fuel, a safe storage system for the gas must be found. Metal clusters that release hydrogen in response to an electric current may be a step in the right direction.

Masanori Takimoto and Zhaomin Hou

doi:10.1038/443400a

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Evolution: Different paths to the same end p401

Genetic dissection of a yeast gene-regulatory pathway shows that the logical output of such a pathway can remain the same even though the molecular mechanisms underlying the output have diverged remarkably.

Antonis Rokas

doi:10.1038/443401a

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Condensed-matter physics: Coherent questions p403

Bose–Einstein condensation occurs when many particles enter into the same, coherent quantum state, and is now claimed to occur in various systems of 'quasiparticles' in solids. But is it the right term to use here?

David Snoke

doi:10.1038/443403a

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Ageing: Balancing regeneration and cancer p404

The proliferation of cells must balance the longevity assured by tissue renewal against the risk of developing cancer. The tumour-suppressor protein p16^INK4a seems to act at the pivot of this delicate equilibrium.

Christian M Beausejour and Judith Campisi

doi:10.1038/nature05221

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Climate change: A nasty surprise in the greenhouse p405

The Kyoto Protocol aims to reduce emissions of greenhouse gases such as methane. But it seems that the fall in human-induced methane emissions in the 1990s was only transitory, and atmospheric methane might rise again.

Jos Lelieveld

doi:10.1038/443405a

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Brief Communications

Biomaterials: Silk-like secretion from tarantula feet p407

Stanislav N Gorb, Senta Niederegger, Cheryl Y Hayashi, Adam P Summers, Walter Vötsch and Paul Walther

doi:10.1038/443407a

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Brief Communications Arising

Plant genetics: Increased outcrossing in hothead mutants pE8

Peng Peng, Simon W.-L. Chan, Govind A. Shah and Steve E. Jacobsen

doi:10.1038/nature05251

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Increased outcrossing in hothead mutants (Reply) pE8

Susan J. Lolle, Robert E. Pruitt, J. L. Victor and J. M. Young

doi:10.1038/nature05252

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Articles

Bose–Einstein condensation of exciton polaritons p409

J. Kasprzak, M. Richard, S. Kundermann, A. Baas, P. Jeambrun, J. M. J. Keeling, F. M. Marchetti, M. H. Szymaska, R. André, J. L. Staehli, V. Savona, P. B. Littlewood, B. Deveaud and Le Si Dang

doi:10.1038/nature05131

Abstract | Full Text | PDF (2,573K) | Supplementary information

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Evolution of alternative transcriptional circuits with identical logic p415

Annie E. Tsong, Brian B. Tuch, Hao Li and Alexander D. Johnson

doi:10.1038/nature05099

Abstract | Full Text | PDF (2,099K) | Supplementary information

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16^INK4a p421

Viktor Janzen, Randolf Forkert, Heather E. Fleming, Yoriko Saito, Michael T. Waring, David M. Dombkowski, Tao Cheng, Ronald A. DePinho, Norman E. Sharpless and David T. Scadden

doi:10.1038/nature05159

Abstract | Full Text | PDF (1,013K) | Supplementary information

See also: Editor's summary | News and Views by Beausejour & Campisi

Letters

Infall of gas as the formation mechanism of stars up to 20 times more massive than the Sun p427

Maria T. Beltrán, Riccardo Cesaroni, Claudio Codella, Leonardo Testi, Ray S. Furuya and Luca Olmi

doi:10.1038/nature05074

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Bose–Einstein condensation of quasi-equilibrium magnons at room temperature under pumping p430

S. O. Demokritov, V. E. Demidov, O. Dzyapko, G. A. Melkov, A. A. Serga, B. Hillebrands and A. N. Slavin

doi:10.1038/nature05117

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Violation of the incompressibility of liquid by simple shear flow p434

Akira Furukawa and Hajime Tanaka

doi:10.1038/nature05119

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Contribution of anthropogenic and natural sources to atmospheric methane variability p439

P. Bousquet, P. Ciais, J. B. Miller, E. J. Dlugokencky, D. A. Hauglustaine, C. Prigent, G. R. Van der Werf, P. Peylin, E.-G. Brunke, C. Carouge, R. L. Langenfelds, J. Lathière, F. Papa, M. Ramonet, M. Schmidt, L. P. Steele, S. C. Tyler and J. White

doi:10.1038/nature05132

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Continental-scale patterns of canopy tree composition and function across Amazonia p444

Hans ter Steege, Nigel C. A. Pitman, Oliver L. Phillips, Jerome Chave, Daniel Sabatier, Alvaro Duque, Jean-François Molino, Marie-Françoise Prévost, Rodolphe Spichiger, Hernán Castellanos, Patricio von Hildebrand and Rodolfo Vásquez

doi:10.1038/nature05134

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Increasing p16^INK4a expression decreases forebrain progenitors and neurogenesis during ageing p448

Anna V. Molofsky, Shalom G. Slutsky, Nancy M. Joseph, Shenghui He, Ricardo Pardal, Janakiraman Krishnamurthy, Norman E. Sharpless and Sean J. Morrison

doi:10.1038/nature05091

First paragraph | Full Text | PDF (362K) | Supplementary information

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p16^INK4a induces an age-dependent decline in islet regenerative potential p453

Janakiraman Krishnamurthy, Matthew R. Ramsey, Keith L. Ligon, Chad Torrice, Angela Koh, Susan Bonner-Weir and Norman E. Sharpless

doi:10.1038/nature05092

First paragraph | Full Text | PDF (438K) | Supplementary information

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BRX mediates feedback between brassinosteroid levels and auxin signalling in root growth p458

Céline F. Mouchel, Karen S. Osmont and Christian S. Hardtke

doi:10.1038/nature05130

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Centrosome polarization delivers secretory granules to the immunological synapse p462

Jane C. Stinchcombe, Endre Majorovits, Giovanna Bossi, Stephen Fuller and Gillian M. Griffiths

doi:10.1038/nature05071

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Structural insights into yeast septin organization from polarized fluorescence microscopy p466

Alina M. Vrabioiu and Timothy J. Mitchison

doi:10.1038/nature05109

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Ion permeation through the Na⁺,K⁺-ATPase p470

Nicolás Reyes and David C. Gadsby

doi:10.1038/nature05129

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Naturejobs

Prospects p475

Paul Smaglik

doi:10.1038/nj7110-475a

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Building a better foundation p476

Europeans have traditionally expected their governments to fund research. But foundations are hoping to play a major new role, says Gene Russo.

Gene Russo

doi:10.1038/nj7110-476a

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Haifan Lin, director, stem-cell programme, Yale University, New Haven, Connecticut p478

Virginia Gewin

doi:10.1038/nj7110-478a

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Investing in people p478

Sohaila Rastan

doi:10.1038/nj7110-478b

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Sounds of scientists p478

Milan de Vries

doi:10.1038/nj7110-478c

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Highlight: Germany

doi:10.1038/nj0125

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Futures

Twenty2 p480

The city without secrets.

Nate Balding

doi:10.1038/443480a

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