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Nature 441, 143-145 (11 May 2006) | doi:10.1038/441143a; Published online 10 May 2006

Epigenetics: Unfinished symphony

Jane Qiu1

  1. Jane Qiu is an editor at Nature Reviews Neuroscience.
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To correctly 'play' the DNA score in our genome, cells must read another notation that overlays it — the epigenetic code. A global effort to decode it is now in the making, reports Jane Qiu.

Manel Esteller's phone did not stop ringing for weeks. It was summer 2005, and he and his team at the Spanish National Cancer Centre in Madrid had just published a study comparing the activity of DNA in identical twins.

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