Table of contents
Volume 438 Number 7067 pp395-530
In this issue (24 November 2005)
Also this week
(this content only available online) indicates content that is available online only
Editorials
Networks for Africa p395
The future of science and technology in Africa depends on the development of mutually supportive networks. Two examples show how imaginative initiatives can be turned into models for others.
doi:10.1038/435395a
The heat is on p396
A successor to the Kyoto Protocol on climate change must involve mandatory emissions caps.
doi:10.1038/435396a
Life is what you make it p396
This issue celebrates the emerging field of synthetic biology.
doi:10.1038/435396b
News
Google makes data free for all p400
Project could lead to more 'intelligent' web pages.
Declan Butler
doi:10.1038/438400a
US watchdog finds bias against morning-after pill p401
Drug agency accused of mixing politics with science.
Meredith Wadman
doi:10.1038/438401a
Sidelines p402
doi:10.1038/438402a
Neuroscientists put gene therapy into reverse p402
Making the disease could break the disease.
Jim Giles
doi:10.1038/438402b
Seals net data from cold seas p402
Tagged animals to be used as remote sensors.
Tom Simonite
doi:10.1038/438402c
Korean stem-cell crisis deepens p405
Fertility specialist admits buying human eggs.
David Cyranoski
doi:10.1038/438405a
Deal on toxicity law fails to appease p406
EU draws up compromise for chemical-safety legislation.
Alison Abbott
doi:10.1038/438406a
China steps up drive to vaccinate all domestic birds p406
Officials claim 8 billion birds inoculated so far.
David Cyranoski
doi:10.1038/438406b
Software shakes up schizophrenia diagnosis p407
Brain scan analysis could reveal disease before symptoms.
Jennifer Wild
doi:10.1038/438407a
News Features
Energy in California: Power struggle p410
For decades, California has bucked the US trend of gobbling ever more electricity. But can the state pull off an even more ambitious goal and slash its greenhouse-gas emissions? Charles Petit finds out.
doi:10.1038/438410a
Antarctic astronomy: Seeing in the dark p414
When darkness falls for Antarctica's long winter months, the sky becomes a spectacular canopy of stars. At one brand new base, astronomers are braving the extreme cold to build telescopes that they hope will rival space observatories. Gabrielle Walker investigates.
doi:10.1038/438414a
See also: Editor's summary
Synthetic biology: Designs on life p417
Earlier this month, students from around the world locked horns in competition. Their challenge was to build functioning devices out of biological parts. Erika Check finds out how they got on.
doi:10.1038/438417a
Business
Property rights go East p420
China's approach to patents is undergoing a sharp transition, as David Cyranoski reports.
doi:10.1038/438420a
Market watch p421
Colin Macilwain
doi:10.1038/437421b
In brief p421
doi:10.1038/438421a
Correspondence
Bush's policy stopped US gaining stem-cell lead p422
Robert Lanza and Ronald M. Green
doi:10.1038/438422a
Evidence of group learning does not add up to culture p422
William L. Abler
doi:10.1038/438422b
Is the ID debate proof of an intelligent deceiver? p422
A. Richard Palmer
doi:10.1038/438422c
See also: Editor's summary
Librarians can help prevent accidental plagiarism p422
Keith Nockels
doi:10.1038/438422d
Commentary
Let us go forth and safely multiply p423
Synthetic biology, which involves the engineering of new biological components and organisms and the redesign of existing ones, will require community discipline and openness if it is to flourish safely, says George Church.
doi:10.1038/438423a
See also: Editor's summary
Books and Arts
All the fun of the fare p425
A selection of amusing morsels from the history of nutrition science.
Marion Nestle reviews Terrors of the Table: The Curious History of Nutrition by Walter Gratzer
doi:10.1038/438425a
Unearthing mammalian origins p426
Timothy Rowe reviews Mammals From the Age of Dinosaurs: Origins, Evolution, and Structure by Zofia Kielan-Jaworowska, Richard L. Cifelli and Zhe-Xi Luo
doi:10.1038/438426a
See also: Editor's summary
A poisonous present p427
Benno Müller-Hill reviews Kampfstoff-Forschung im Nationalsozialismus: Zur Kooperation von Kaiser-Wilhelm-Instituten, Militär und Industrie [Weapons Research in National Socialism] by Florian Schmaltz
doi:10.1038/438427a
The latest on latex p427
Robert W. Cahn reviews Tears of the Tree: The Story of Rubber — A Modern Marvel by John Loadman
doi:10.1038/438427b
Installation: Uranium days p428
Sylvie Coyaud reviews The Children of Uranium
doi:10.1038/438428a
Essay
ConceptPushing for power p429
Tales of brilliant scientists and their heroic discoveries can overshadow the true nature of scientific communities, which are often dominated by battles for power and success.
Ad Lagendijk
doi:10.1038/438429a
News and Views
Quantum computing: A bit chilly p431
A quantum computer needs a constant supply of 'qubits' in a known state. A nuclear magnetic resonance experiment that cools qubits by pumping entropy into a heat bath is a step closer to that goal.
Leonard J. Schulman
doi:10.1038/438431a
See also: Editor's summary
Cell biology: Silenced RNA on the move p432
Proteins are often produced at their site of action, but the RNAs from which they are made must be kept inactive until they reach the right spot. It seems this 'silencing' of RNA is linked to its transport around the cell.
Ralf Dahm and Michael Kiebler
doi:10.1038/438432a
50 & 100 years ago p433
doi:10.1038/438433a
Condensed-matter physics: Focus on the Fermi surface p435
The electrical resistance of some manganese oxides takes a tumble when they become magnetic. Close examination confirms the interplay of conduction electrons and lattice vibrations that contributes to this effect.
Peter Littlewood
and 
imon Kos
doi:10.1038/438435a
See also: Editor's summary
Photonics: Wingèd light p436
Amber Jenkins
doi:10.1038/438436a
Obesity: Aquaporin enters the picture p436
The aquaporins are membrane channels that were originally identified as regulators of a cell's water balance. A member of the aquaporin family is now implicated as a central agent in controlling fat metabolism.
Gema Frühbeck
doi:10.1038/438436b
Histocompatibility: Colonial match and mismatch p437
Distinguishing self from non-self is the underlying basis of immunity. Intriguingly, the genetic system that governs a natural process akin to tissue transplantation in vertebrates has been characterized in an invertebrate.
Gary W. Litman
doi:10.1038/438437a
See also: Editor's summary
Brief Communications
Synthetic biology: Engineering Escherichia coli to see light p441
These smart bacteria 'photograph' a light pattern as a high-definition chemical image.
Anselm Levskaya, Aaron A. Chevalier, Jeffrey J. Tabor, Zachary Booth Simpson, Laura A. Lavery, Matthew Levy, Eric A. Davidson, Alexander Scouras, Andrew D. Ellington, Edward M. Marcotte and Christopher A. Voigt
doi:10.1038/nature04405
First paragraph | Full Text | PDF (297K) | Supplementary information
See also: Editor's summary
Insect communication: 'No entry' signal in ant foraging p442
Elva J. H. Robinson, Duncan E. Jackson, Mike Holcombe and Francis L. W. Ratnieks
doi:10.1038/438442a
First paragraph | Full Text | PDF (165K) | Supplementary information
See also: Editor's summary
Top of page
Brief Communications Arising
Immunology: Insulin auto-antigenicity in type 1 diabetes pE5
Darcy B. Wilson
doi:10.1038/nature04423
First paragraph | Full Text | PDF (89K)
Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply) pE5
David A. Hafler, Sally C. Kent, Yahua Chen, Lisa Bregoli, Sue M. Clemmings, Bernhard Hering, Norma Sue Kenyon and Camillo Ricordi
doi:10.1038/nature04424
First paragraph | Full Text | PDF (94K)
Reviews
Reconstruction of genetic circuits p443
David Sprinzak and Michael B. Elowitz
doi:10.1038/nature04335
Abstract | Full Text | PDF (404K)
See also: Editor's summary
Foundations for engineering biology p449
Drew Endy
doi:10.1038/nature04342
Abstract | Full Text | PDF (291K)
See also: Editor's summary | Authors
Articles
Isolation and characterization of a protochordate histocompatibility locus p454
Anthony W. De Tomaso, Spencer V. Nyholm, Karla J. Palmeri, Katherine J. Ishizuka, William B. Ludington, Katrina Mitchel and Irving L. Weissman
doi:10.1038/nature04150
Abstract | Full Text | PDF (309K) | Supplementary information
See also: Editor's summary | News and Views by Litman
Direct observation of base-pair stepping by RNA polymerase p460
Elio A. Abbondanzieri, William J. Greenleaf, Joshua W. Shaevitz, Robert Landick and Steven M. Block
doi:10.1038/nature04268
Abstract | Full Text | PDF (1,415K) | Supplementary information
See also: Editor's summary
Letters
Direct detection of a magnetic field in the innermost regions of an accretion disk p466
Jean-François Donati, Fréderic Paletou, Jérome Bouvier and Jonathan Ferreira
doi:10.1038/nature04253
First paragraph | Full Text | PDF (214K) | Supplementary information
See also: Editor's summary
Experimental implementation of heat-bath algorithmic cooling using solid-state nuclear magnetic resonance p470
J. Baugh, O. Moussa, C. A. Ryan, A. Nayak and R. Laflamme
doi:10.1038/nature04272
First paragraph | Full Text | PDF (448K)
See also: Editor's summary | News and Views by Schulman
Nodal quasiparticle in pseudogapped colossal magnetoresistive manganites p474
N. Mannella, W. L. Yang, X. J. Zhou, H. Zheng, J. F. Mitchell, J. Zaanen, T. P. Devereaux, N. Nagaosa, Z. Hussain and Z.-X. Shen
doi:10.1038/nature04273
First paragraph | Full Text | PDF (793K)
See also: Editor's summary | News and Views by Littlewood & Kos
Probing carrier dynamics in nanostructures by picosecond cathodoluminescence p479
M. Merano, S. Sonderegger, A. Crottini, S. Collin, P. Renucci, E. Pelucchi, A. Malko, M. H. Baier, E. Kapon, B. Deveaud and J.-D. Ganière
doi:10.1038/nature04298
First paragraph | Full Text | PDF (425K)
Impacts of orbital forcing and atmospheric carbon dioxide on Miocene ice-sheet expansion p483
Ann Holbourn, Wolfgang Kuhnt, Michael Schulz and Helmut Erlenkeuser
doi:10.1038/nature04123
First paragraph | Full Text | PDF (845K) | Supplementary information
See also: Authors
Density of hydrous silicate melt at the conditions of Earth's deep upper mantle p488
Kyoko N. Matsukage, Zhicheng Jing and Shun-ichiro Karato
doi:10.1038/nature04241
First paragraph | Full Text | PDF (347K)
The entomological inoculation rate and Plasmodium falciparum infection in African children p492
D. L. Smith, J. Dushoff, R. W. Snow and S. I. Hay
doi:10.1038/nature04024
First paragraph | Full Text | PDF (199K)
See also: Editor's summary | Authors
Eye-specific effects of binocular rivalry in the human lateral geniculate nucleus p496
John-Dylan Haynes, Ralf Deichmann and Geraint Rees
doi:10.1038/nature04169
First paragraph | Full Text | PDF (256K) | Supplementary information
See also: Editor's summary
Neural measures reveal individual differences in controlling access to working memory p500
Edward K. Vogel, Andrew W. McCollough and Maro G. Machizawa
doi:10.1038/nature04171
First paragraph | Full Text | PDF (357K)
See also: Editor's summary
Design principles of a bacterial signalling network p504
Markus Kollmann, Linda Løvdok, Kilian Bartholomé, Jens Timmer and Victor Sourjik
doi:10.1038/nature04228
First paragraph | Full Text | PDF (265K) | Supplementary information
The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation p508
Uttiya Basu, Jayanta Chaudhuri, Craig Alpert, Shilpee Dutt, Sheila Ranganath, Gang Li, Jason Patrick Schrum, John P. Manis and Frederick W. Alt
doi:10.1038/nature04255
First paragraph | Full Text | PDF (362K) | Supplementary information
Spatial regulation of 
-actin translation by Src-dependent phosphorylation of ZBP1 p512
Stefan Hüttelmaier, Daniel Zenklusen, Marcell Lederer, Jason Dictenberg, Mike Lorenz, XiuHua Meng, Gary J. Bassell, John Condeelis and Robert H. Singer
doi:10.1038/nature04115
First paragraph | Full Text | PDF (350K) | Supplementary information
See also: News and Views by Dahm & Kiebler
Structures of ParB bound to DNA reveal mechanism of partition complex formation p516
Maria A. Schumacher and Barbara E. Funnell
doi:10.1038/nature04149
First paragraph | Full Text | PDF (387K) | Supplementary information
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA p520
T. Martin Schmeing, Kevin S. Huang, Scott A. Strobel and Thomas A. Steitz
doi:10.1038/nature04152
First paragraph | Full Text | PDF (466K) | Supplementary information
See also: Editor's summary
Naturejobs
ProspectTurning the tables p525
It's time to make sure foreign students feel welcome.
Paul Smaglik
doi:10.1038/nj7067-525a
Special Report
Save the world and keep a career p526
If the prospect of endless lab work doesn't appeal, maybe using your qualifications to address global problems more directly would be the answer. There is plenty of scope for those who wish to pursue science with a 'social conscience', as Virginia Gewin finds out.
Virginia Gewin
doi:10.1038/nj7067-526a
Career Views
Richard Somiari, president and chief scientific officer, ITSI-Biosciences, Johnstown, Pennsylvania p528
Native Nigerian journeys from food technology to proteomics.
Corie Lok
doi:10.1038/nj7067-528a
Bricks & Mortar p528
University of Pittsburgh facility houses mix of departments and facilities.
Kendall Powell
doi:10.1038/nj7067-528b
Graduate Journal: Who needs evidence? p528
Pondering the 'benefits' of intelligent design.
Jason Underwood
doi:10.1038/nj7067-528c
