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Review

Nature 438, 449-453 (24 November 2005) | doi:10.1038/nature04342

Open Innovation Challenges

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Foundations for engineering biology

Drew Endy1

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Engineered biological systems have been used to manipulate information, construct materials, process chemicals, produce energy, provide food, and help maintain or enhance human health and our environment. Unfortunately, our ability to quickly and reliably engineer biological systems that behave as expected remains quite limited. Foundational technologies that make routine the engineering of biology are needed. Vibrant, open research communities and strategic leadership are necessary to ensure that the development and application of biological technologies remains overwhelmingly constructive.

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