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Editorials

Taking a stand on animal-rights violence p1

Governments must not turn a blind eye to intimidation and violence by animal-rights activists. A more resilient approach is needed.

doi: 10.1038/438001a


Turkey's evolution p1

Admission to the European Union can benefit Turkish science.

doi: 10.1038/438001b


Clamp down on copycats p2

Plagiarism is on the rise, thanks to the Internet. Universities and journals need to take action.

doi: 10.1038/438002a


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Research Highlights

Research highlights p4

doi: 10.1038/438004a


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News

Wartime tactic doubles power of scarce bird-flu drug p6

Use of common drug could stretch world stocks of Tamiflu.

Declan Butler

doi: 10.1038/438006a


Drug firms donate compounds for anti-HIV gel p6

Promising results raise hopes in the battle against AIDS.

Narelle Towie

doi: 10.1038/438006b


Universities scramble to assess scope of falsified results p7

MIT immunologist sacked for scientific misconduct.

Rex Dalton

doi: 10.1038/438007a


Sidelines p8

doi: 10.1038/438008a


Protists push animals aside in rule revamp p8

Redefined kingdoms give centre stage to single-celled organisms.

Tom Simonite

doi: 10.1038/438008b


Turkish rectors rally in support of university head thrown in jail p8

Dispute highlights tension between academic system and religion.

Alison Abbott

doi: 10.1038/438008c


Floods fail to save canyon beaches p10

River ecosystem might never return to normal.

Rex Dalton

doi: 10.1038/438010a


Expert witness: the scientists who testified against intelligent design p11

Researchers tell the tale of defending Darwin in the dock.

doi: 10.1038/438011a


Gene study raises fears for three-parent babies p12

Concern grows over mixing of mitochondrial DNA during assisted reproduction.

Erika Check

doi: 10.1038/438012a


News in brief p13

doi: 10.1038/438013a


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News Features

Evolutionary theory: Personal effects p14

Living things from bacteria to humans change their environment, but the consequences for evolution and ecology are only now being understood, or so the 'niche constructivists' claim. Dan Jones investigates.

doi: 10.1038/438014a


Star of the south p18

This month South Africa will officially open the largest optical telescope in the Southern Hemisphere. But is the country ready to capitalize on its investment? Michael Cherry investigates.

doi: 10.1038/438018a


Meteorology: Winds of change p21

Hurricanes can grow more intense in a matter of hours, but exactly why remains a mystery. Mark Schrope flies into the eye of a storm to investigate.

doi: 10.1038/438021a

See also: Editor's summary


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Business

Race is on for flu vaccine p23

Drug companies are using adjuvants to boost their vaccines in a bid to be ready for a flu pandemic, as Meredith Wadman reports.

Meredith Wadman

doi: 10.1038/438023a


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Correspondence

UK must go on promoting and funding science p24

David A. King

doi: 10.1038/438024a


Universal fungus register offers pattern for zoology p24

David L. Hawksworth

doi: 10.1038/438024b


Mapping the complexities of science and politics p24

Ying-Hen Hsieh

doi: 10.1038/438024c


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Books and Arts

Scientists on screen p25

Does Hollywood think we're all dangerous megalomaniacs with crazy hair?

Adam Rutherford reviews Mad, Bad and Dangerous: The Scientist and the Cinema by Christopher Frayling

doi: 10.1038/438025a


Return to the fortress p26

Michael Fitzpatrick reviews The Science and Fiction of Autism by Laura Schreibman

doi: 10.1038/438026a


Green in tooth and claw p27

Peter D. Moore reviews Demons in Eden: The Paradox of Plant Diversity by Jonathan Silvertown

doi: 10.1038/438027a


Exhibition: In the croak room p27

doi: 10.1038/438027b


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Essay

Concept

Wit and wisdom p29

From pioneering xerographer to innovative teacher, Georg Christoph Lichtenberg was a physicist with many skills, but perhaps most remembered will be his acerbic aphorisms.

John L. Heilbron

doi: 10.1038/438029a


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News and Views

Intelligence: A gender bender p31

The conclusion of a number-crunching exercise on various data sets is that male university students have significantly higher IQs than their female counterparts. But the methodology used is deeply flawed.

Steve Blinkhorn

doi: 10.1038/438031a


Astronomy: Light on a dark place p32

The sharpest images ever taken of matter around the probable black hole at the centre of our Galaxy bring us within grasp of a crucial test of general relativity — a picture of the black hole's 'point of no return'.

Christopher Reynolds

doi: 10.1038/438032a

See also: Editor's summary


Microbiology: Algae and the vitamin mosaic p33

The requirements for vitamin B12 vary among algal species in a seemingly inexplicable pattern. A study that exploits genomic data now provides enlightenment — and evidence of symbioses with bacteria.

Robert A. Andersen

doi: 10.1038/438033a

See also: Editor's summary


Global change: Sea level and volcanoes p35

Large volcanic eruptions cool the world ocean. In doing so, they temporarily reduce the increase in ocean heat content and the rise in sea level attributed to warming caused by greenhouse-gas emissions.

Anny Cazenave

doi: 10.1038/438035a

See also: Editor's summary


50 & 100 years ago p35

doi: 10.1038/438035b


Structural biology: Proteins flex to function p36

Static pictures of protein structures are so prevalent that it is easy to forget they are dynamic molecular machines. Characterizing their intrinsic motions may be necessary to understand how they work.

Yuanpeng J. Huang and Gaetano T. Montelione

doi: 10.1038/438036a

See also: Editor's summary


Cosmology: The infrared dawn of starlight p39

The modest-sized but successful Spitzer Space Telescope has detected fluctuations in cosmic light at infrared frequencies. Is this the signature of the first population of stars that formed in the Universe?

Richard S. Ellis

doi: 10.1038/438039a

See also: Editor's summary


Chemical biology: Bring them back alive p40

A deep search has turned up an RNA that can carry out the chemically complex 'aldol' reaction involved in sugar metabolism. Could this be similar to an ancestral catalyst that existed billions of years ago?

Michael Yarus

doi: 10.1038/438040a


Correction p40

doi: 10.1038/438040b


Obituary: Richard Doll (1912–2005) p41

Epidemiologist extraordinary.

Leo Kinlen

doi: 10.1038/438041a


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Brief Communications

Theoretical mechanics: Crowd synchrony on the Millennium Bridge p43

Footbridges start to sway when packed with pedestrians falling into step with their vibrations.

Steven H. Strogatz, Daniel M. Abrams, Allan McRobie, Bruno Eckhardt and Edward Ott

doi: 10.1038/43843a

See also: Editor's summary


Nanoscale hydrodynamics: Enhanced flow in carbon nanotubes p44

Mainak Majumder, Nitin Chopra, Rodney Andrews and Bruce J. Hinds

doi: 10.1038/43844a


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Brief Communications Arising

Ecology: Is speciation driven by species diversity? pE1

Carlos Daniel Cadena, Robert E. Ricklefs, Iván Jiménez and Eldredge Bermingham

doi: 10.1038/nature04308


Ecology: Is speciation driven by species diversity? (Reply) pE2

Brent C. Emerson and Niclas Kolm

doi: 10.1038/nature04309


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Articles

Tracing the first stars with fluctuations of the cosmic infrared background p45

A. Kashlinsky, R. G. Arendt, J. Mather and S. H. Moseley

doi: 10.1038/nature04143

See also: Editor's summary | News and Views by Ellis


Radiocarbon dating of interstratified Neanderthal and early modern human occupations at the Chatelperronian type-site p51

Brad Gravina, Paul Mellars and Christopher Bronk Ramsey

doi: 10.1038/nature04006

See also: Editor's summary


The yeast Pif1p helicase removes telomerase from telomeric DNA p57

Jean-Baptiste Boulé, Leticia R. Vega and Virginia A. Zakian

doi: 10.1038/nature04091

See also: Editor's summary


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Letters

A size of approxau for the radio source Sgr A* at the centre of the Milky Way p62

Zhi-Qiang Shen, K. Y. Lo, M.-C. Liang, Paul T. P. Ho and J.-H. Zhao

doi: 10.1038/nature04205

See also: Editor's summary | News and Views by Reynolds


Active control of slow light on a chip with photonic crystal waveguides p65

Yurii A. Vlasov, Martin O'Boyle, Hendrik F. Hamann and Sharee J. McNab

doi: 10.1038/nature04210

See also: Editor's summary


Simulating micrometre-scale crystal growth from solution p70

Stefano Piana, Manijeh Reyhani and Julian D. Gale

doi: 10.1038/nature04173


Significant decadal-scale impact of volcanic eruptions on sea level and ocean heat content p74

John A. Church, Neil J. White and Julie M. Arblaster

doi: 10.1038/nature04237

See also: News and Views by Cazenave


Crustal rheology of the Himalaya and Southern Tibet inferred from magnetotelluric data p78

M. J. Unsworth, A. G. Jones, W. Wei, G. Marquis, S. G. Gokarn, J. E. Spratt and The INDEPTH-MT team

doi: 10.1038/nature04154

See also: Editor's summary | Authors


Proteorhodopsin in the ubiquitous marine bacterium SAR11 p82

Stephen J. Giovannoni, Lisa Bibbs, Jang-Cheon Cho, Martha D. Stapels, Russell Desiderio, Kevin L. Vergin, Michael S. Rappé, Samuel Laney, Lawrence J. Wilhelm, H. James Tripp, Eric J. Mathur and Douglas F. Barofsky

doi: 10.1038/nature04032

See also: Editor's summary


Photosynthesis genes in marine viruses yield proteins during host infection p86

Debbie Lindell, Jacob D. Jaffe, Zackary I. Johnson, George M. Church and Sallie W. Chisholm

doi: 10.1038/nature04111

See also: Editor's summary


Algae acquire vitamin B12 through a symbiotic relationship with bacteria p90

Martin T. Croft, Andrew D. Lawrence, Evelyne Raux-Deery, Martin J. Warren and Alison G. Smith

doi: 10.1038/nature04056

See also: Editor's summary | News and Views by Andersen | Authors


The transcription factor Engrailed-2 guides retinal axons p94

Isabelle Brunet, Christine Weinl, Michael Piper, Alain Trembleau, Michel Volovitch, William Harris, Alain Prochiantz and Christine Holt

doi: 10.1038/nature04110


Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion p99

Ronald S. Veazey, Per Johan Klasse, Susan M. Schader, Qinxue Hu, Thomas J. Ketas, Min Lu, Preston A. Marx, Jason Dufour, Richard J. Colonno, Robin J. Shattock, Martin S. Springer and John P. Moore

doi: 10.1038/nature04055

See also: Editor's summary | Authors


A protein interaction network of the malaria parasite Plasmodium falciparum p103

Douglas J. LaCount, Marissa Vignali, Rakesh Chettier, Amit Phansalkar, Russell Bell, Jay R. Hesselberth, Lori W. Schoenfeld, Irene Ota, Sudhir Sahasrabudhe, Cornelia Kurschner, Stanley Fields and Robert E. Hughes

doi: 10.1038/nature04104

See also: Editor's summary


The Plasmodium protein network diverges from those of other eukaryotes p108

Silpa Suthram, Taylor Sittler and Trey Ideker

doi: 10.1038/nature04135

See also: Editor's summary


A putative stimulatory role for activator turnover in gene expression p113

J. Russell Lipford, Geoffrey T. Smith, Yong Chi and Raymond J. Deshaies

doi: 10.1038/nature04098


Intrinsic dynamics of an enzyme underlies catalysis p117

Elan Z. Eisenmesser, Oscar Millet, Wladimir Labeikovsky, Dmitry M. Korzhnev, Magnus Wolf-Watz, Daryl A. Bosco, Jack J. Skalicky, Lewis E. Kay and Dorothee Kern

doi: 10.1038/nature04105

See also: Editor's summary | News and Views by Huang & Montelione


Erratum: Marine microorganisms and global nutrient cycles p122

Kevin R. Arrigo

doi: 10.1038/nature04265


Corrigendum: Eocene bipolar glaciation associated with global carbon cycle changes p122

Aradhna Tripati, Jan Backman, Henry Elderfield and Patrizia Ferretti

doi: 10.1038/nature04289


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Naturejobs

Prospect

A transparent process p123

European recruitment would benefit from greater transparency.

Paul Smaglik

doi:10.1038/nj7064-123a


Career Views

Hendricus Hoogenboom, chief scientific officer, Ablynx, Ghent, Belgium p126

Antibody expert pursues nanobiotechnology.

Janet Wright

doi:10.1038/nj7064-126a


Scientists & Societies p126

Dutch postdocs retreat to discuss career development.

Erik van Beers, Anke Klerkx & Andrea Thiele

doi:10.1038/nj7064-126b


Graduate journal: Endurance test p126

Finishing a PhD is like running a marathon.

Anne Margaret Lee

doi:10.1038/nj7064-126c


Spotlight

Spotlight on Italy

doi:10.1038/nj0095


Highlights

Special Feature: Training the Next Generation of Academic Physicians

doi:10.1038/nj0096


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Futures

Shopping p128

Scott Seller-Mason

doi: 10.1038/438128a


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