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Nature 434, 952-953 (21 April 2005) | doi:10.1038/434952a; Published online 20 April 2005

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Image manipulation:  CSI: cell biology

Helen Pearson1

  1. Helen Pearson reports for news@nature.com from New York.

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Digital photography and image-manipulation software allow biologists to tweak their data as never before. But there's a fine line between acceptable enhancements and scientific misconduct. Helen Pearson investigates.

In a cramped office in midtown Manhattan, a forensics expert peers intently at a flickering computer screen. The shadowy image, hugely magnified, reveals a tell-tale dark smear.

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