Supplementary information
From the following article:
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
Trude H. Flo, Kelly D. Smith, Shintaro Sato, David J. Rodriguez, Margaret A. Holmes, Roland K. Strong, Shizuo Akira and Alan Aderem
Nature 432, 917-921(16 December 2004)
doi:10.1038/nature03104
Supplementary Figure 1
Targeted disruption of the mouse Lcn2 gene.
Supplementary Figure 2
Liver inflammation, spleen iron and infiltrating neutrophils after i.p. infection of lipocalin 2 knockout (-/-) and wild type (+/+) mice with 0.6 ´ 108 c.f.u. E. coli H9049.
Supplementary Figure 3
Lipocalin 2 deficiency does not affect induction apoptosis upon withdrawal of IL-3 from IL-3-dependent bone marrow cells.
Supplementary Table 1
Blood and peritoneal cell populations in lipocalin 2-deficient and WT mice.
Supplementary Table 2
Serum iron and iron binding capacities in lipocalin 2 deficient and wild-type mice.
Supplementary Figure Legends
Legends to accompany Supplementary Information Figures 1–3.
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