Table of contents
Volume 430 Number 7003 pp951-1065
(this content only available online) indicates content that is available online only
Editorials
Share issues p951
The US National Institutes of Health is toughening its funding rules to persuade researchers to share materials more widely. The move is commendable but it raises critical questions that urgently require resolution.
doi:10.1038/430951a
A matter of interest p951
The biotech industry's top lobbyist faces a problem he was quick to raise as a Congressman: apparent conflict of interest.
doi:10.1038/430951b
News
Universities unnerved by revised rules for sharing NIH research p953
Researchers face rush to amend grant applications
Charles Jennings
doi:10.1038/430953a
Analysis highlights suicide risk of antidepressants p954
Children at risk from 'off-label' prescriptions
Erika Check
doi:10.1038/430954a
Beagle team hounds space agency over lost lander p954
Internal report rebuts claims of management failures
Mark Peplow
doi:10.1038/430954b
Bird flu data languish in Chinese journals p955
Health authorities in the dark as warnings go untranslated
David Cyranoski
doi:10.1038/430955a
Greenland ice sheet to get underhand inspection p955
Robot sub prepares for most dangerous mission yet
Amanda Haag
doi:10.1038/430955b
Brickbats for fossil hunter who claims skull has false tooth p956
Researchers react to critics of work on oldest human relative
Rex Dalton
doi:10.1038/430956a
Superconductor beats copper in plans for particle collider p956
German technology gets go-ahead for next-generation experiment
Geoff Brumfiel and David Cyranoski
doi:10.1038/430956b
Director's salary makes chemists see red p957
Executive tops science society pay league
Geoff Brumfiel
doi:10.1038/430957a
Canada rings the changes for study of northern birds p957
Ornithologists call on new technology for studies of boreal wilderness
Erika Check
doi:10.1038/430957b
News Features
Scientific espionage: The accidental spy p960
Hiroaki Serizawa's promising US academic career was ruined when a favour to a friend led to him being charged with economic espionage on behalf of Japan. He tells his story to David Cyranoski.
doi:10.1038/430960a
Neuroscience: While you were sleeping p962
Ever woken up with the answer to a problem that had seemed insoluble the night before, or able to perform a task that had previously taxed your skills? We may soon know why, says Laura Nelson.
doi:10.1038/430962a
Correspondence
You don't need a licence (or PhD) to use your brain p965
Do scientists look down on the general public with whom they seek better relations?
David L. Anderson
doi:10.1038/430965a
NIDA's commitment to tackling drug abuse p965
doi:10.1038/430965b
Don't have a cow! Fight global warming with CFC p965
Theodore A. Alston
doi:10.1038/430965c
Books and Arts
Growing biodiversity p967
Your local grocery store shows why variety matters.
Stuart Pimm reviews Farmers' Bounty: Locating Crop Diversity in the Contemporary World by Stephen B. Brush
doi:10.1038/430967a
Myths and men p968
John Galloway reviews Moments of Truth: Four Creators of Modern Medicine by Thomas Dormandy
doi:10.1038/430968a
Science in culture p969
Alex Colville's exhaustive search for mathematical probity.
Martin Kemp reviews
doi:10.1038/430969a
Pathways and building blocks p970
Hans Meinhardt reviews Modularity in Development and Evolution
doi:10.1038/430970a
Essay
ConceptGoing into reverse p971
Reversible computation: how feasible is a computer that is both logically and physically reversible?
Seth Lloyd
doi:10.1038/430971a
News and Views
Anoikis: Cancer and the homeless cell p973
A protein has been identified that enables cells to survive when dislodged from their substrate, and to migrate to new sites in the body. Such a mechanism might give cancer cells a significant advantage.
Lance A. Liotta and Elise Kohn
doi:10.1038/430973a
Materials science: Silicon carbide in contention p974
Silicon carbide is a highly desirable material for high-power electronic devices — more desirable even than silicon. And now the problem of producing large, pure wafers of the carbide could be solved.
Roland Madar
doi:10.1038/430974a
Social evolution: Kinship is relative p975
Kinship fosters the evolution of cooperation. However, a once-heretical theory and an unconventional social organism show that the cooperation-enhancing effect of kinship is sometimes negated.
David C. Queller
doi:10.1038/430975a
Chemical biology: Green fluorescent RNA p976
The future for intracellular imaging looks bright with the development of fluorescent probes made entirely of RNA. The cunning design exploits structural attributes of RNA to detect a variety of small molecules.
Michael Famulok
doi:10.1038/430976a
Transmissible spongiform encephalopathies: Prion proof in progress p977
Whether a protein can transmit disease in mammals has been an open question for some time. The latest test of this idea provides some strong evidence in favour, but is unlikely to end the debate.
Herman K. Edskes and Reed B. Wickner
doi:10.1038/430977a
100 and 50 years ago p978
doi:10.1038/430978a
Galaxy formation: Caught in the act? p979
Which came first, the stars and gas that make up a galaxy, or the giant black hole at its centre? Observations of a distant galaxy, caught as it forms, could help solve this chicken-and-egg problem.
Zoltán Haiman
doi:10.1038/430979a
Plant biology: The benefits of nicotine p980
Amanda Tromans
doi:10.1038/430980a
Immunology: Aid for AID p980
Activation-induced deaminase catalyses two processes that diversify antibodies. But this enzyme need not work alone: a partner links it to its substrate — single-stranded DNA — and to DNA-repair molecules.
Almudena R. Ramiro and Michel C. Nussenzweig
doi:10.1038/430980b
Brief Communications
Experimental psychology: Event timing turns punishment to reward p983
Linking a smell with an electric shock does not always have an aversive effect in flies.
Hiromu Tanimoto, Martin Heisenberg and Bertram Gerber
doi:10.1038/430983a
First paragraph | Full Text | PDF (84K)
Top of page
Brief Communications Arising
Mitochondrial permeability: Dual role for the ADP/ATP translocator?
Andrew P. Halestrap
doi:10.1038/nature02816
First paragraph | Full Text | PDF (44K)
Review
The synthesis of organic and inorganic compounds in evolved stars p985
Sun Kwok
doi:10.1038/nature02862
Abstract | Full Text | PDF (469K)
Article
Replication protein A interacts with AID to promote deamination of somatic hypermutation targets p992
Jayanta Chaudhuri, Chan Khuong and Frederick W. Alt
doi:10.1038/nature02821
Abstract | Full Text | PDF (398K) | Supplementary information
See also: News and Views by Ramiro & Nussenzweig
Letters to Nature
The Lyman-
glow of gas falling into the dark matter halo of a z = 3 galaxy p999
Michael Weidinger, Palle Møller and Johan Peter Uldall Fynbo
doi:10.1038/nature02793
First paragraph | Full Text | PDF (222K)
See also: News and Views by Haiman
A 'checkerboard' electronic crystal state in lightly hole-doped Ca2-xNaxCuO2Cl2 p1001
T. Hanaguri, C. Lupien, Y. Kohsaka, D.-H. Lee, M. Azuma, M. Takano, H. Takagi and J. C. Davis
doi:10.1038/nature02861
First paragraph | Full Text | PDF (459K) | Supplementary information
Detachment fronts and the onset of dynamic friction p1005
Shmuel M. Rubinstein, Gil Cohen and Jay Fineberg
doi:10.1038/nature02830
First paragraph | Full Text | PDF (417K)
Ultrahigh-quality silicon carbide single crystals p1009
Daisuke Nakamura, Itaru Gunjishima, Satoshi Yamaguchi, Tadashi Ito, Atsuto Okamoto, Hiroyuki Kondo, Shoichi Onda and Kazumasa Takatori
doi:10.1038/nature02810
First paragraph | Full Text | PDF (212K) | Supplementary information
See also: News and Views by Madar
Ionic liquids and eutectic mixtures as solvent and template in synthesis of zeolite analogues p1012
Emily R. Cooper, Christopher D. Andrews, Paul S. Wheatley, Paul B. Webb, Philip Wormald and Russell E. Morris
doi:10.1038/nature02860
First paragraph | Full Text | PDF (1,308K) | Supplementary information
Similar meltwater contributions to glacial sea level changes from Antarctic and northern ice sheets p1016
Eelco J. Rohling, Robert Marsh, Neil C. Wells, Mark Siddall and Neil R. Edwards
doi:10.1038/nature02859
First paragraph | Full Text | PDF (513K) | Supplementary information
A Middle Jurassic 'sphenosuchian' from China and the origin of the crocodylian skull p1021
James M. Clark, Xing Xu, Catherine A. Forster and Yuan Wang
doi:10.1038/nature02802
First paragraph | Full Text | PDF (254K) | Supplementary information
Cooperation and competition in pathogenic bacteria p1024
Ashleigh S. Griffin, Stuart A. West and Angus Buckling
doi:10.1038/nature02744
First paragraph | Full Text | PDF (185K)
See also: News and Views by Queller
High rates of N2 fixation by unicellular diazotrophs in the oligotrophic Pacific Ocean p1027
Joseph P. Montoya, Carolyn M. Holl, Jonathan P. Zehr, Andrew Hansen, Tracy A. Villareal and Douglas G. Capone
doi:10.1038/nature02824
First paragraph | Full Text | PDF (341K)
Control of phyllotaxy by the cytokinin-inducible response regulator homologue ABPHYL1 p1031
Anna Giulini, Jing Wang and David Jackson
doi:10.1038/nature02778
First paragraph | Full Text | PDF (270K) | Supplementary information
Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB p1034
Sirith Douma, Theo van Laar, John Zevenhoven, Ralph Meuwissen, Evert van Garderen and Daniel S. Peeper
doi:10.1038/nature02765
First paragraph | Full Text | PDF (561K) | Supplementary information
See also: News and Views by Liotta & Kohn
Argos inhibits epidermal growth factor receptor signalling by ligand sequestration p1040
Daryl E. Klein, Valerie M. Nappi, Gregory T. Reeves, Stanislav Y. Shvartsman and Mark A. Lemmon
doi:10.1038/nature02840
First paragraph | Full Text | PDF (353K) | Supplementary information
Separase-mediated cleavage of cohesin at interphase is required for DNA repair p1044
Koji Nagao, Yoh Adachi and Mitsuhiro Yanagida
doi:10.1038/nature02803
First paragraph | Full Text | PDF (371K) | Supplementary information
Structural basis for glycosphingolipid transfer specificity p1048
Lucy Malinina, Margarita L. Malakhova, Alexei Teplov, Rhoderick E. Brown and Dinshaw J. Patel
doi:10.1038/nature02856
First paragraph | Full Text | PDF (509K) | Supplementary information
Structural rearrangements in the membrane penetration protein of a non-enveloped virus p1053
Philip R. Dormitzer, Emma B. Nason, B. V. Venkataram Prasad and Stephen C. Harrison
doi:10.1038/nature02836
First paragraph | Full Text | PDF (810K) | Supplementary information
The native architecture of a photosynthetic membrane p1058
Svetlana Bahatyrova, Raoul N. Frese, C. Alistair Siebert, John D. Olsen, Kees O. van der Werf, Rienk van Grondelle, Robert A. Niederman, Per A. Bullough, Cees Otto and C. Neil Hunter
doi:10.1038/nature02823
First paragraph | Full Text | PDF (252K) | Supplementary information
Corrigendum: Germline stem cells and follicular renewal in the postnatal mammalian ovary p1062
Joshua Johnson, Jacqueline Canning, Tomoko Kaneko, James K. Pru and Jonathan L. Tilly
doi:10.1038/nature02868
Naturejobs
ProspectsCoping with the inevitable p1063
Paul Smaglik
doi:10.1038/nj7003-1063a
Careers and Recruitment
Driving back diabetes p1064
As Western lifestyles spread around the world, diabetes has become an epidemic. Improved treatments are desperately needed, and the funding is there for those who may be able to help, says Ricki Lewis.
Ricki Lewis
doi:10.1038/nj7003-1064a
