Table of contents
Volume 426 Number 6966 pp481-588
Editorial
Science needs the commission, Sturm und Drang and all p481
Despite its burdensome traditions, the European Commission may be the best hope for funding Europe's basic research.
doi:10.1038/426481a
News
France and Japan lock horns in battle to host research reactor p483
Declan Butler
doi:10.1038/426483a
Shortcomings halt study of Swiss cancer vaccine p484
Quirin Schiermeier
doi:10.1038/426484a
Iraqis draw up blueprint for revitalized science academy p484
Jim Giles
doi:10.1038/426484b
Ship row flags up funding of war in Africa p485
Rex Dalton
doi:10.1038/426485a
Budget cuts force Hong Kong to reduce salaries p485
Carina Dennis
doi:10.1038/426485b
Scientists go to jail to crack substance abuse p486
Emily Singer
doi:10.1038/426486a
Climate study highlights inadequacy of emissions cuts p486
Quirin Schiermeier
doi:10.1038/426486b
Rapid drug trial offers hope to CJD patients p487
Jim Giles
doi:10.1038/426487a
Europe eyes merit-based agency p487
Alison Abbott
doi:10.1038/426487b
News Features
Developmental reprogramming: Take a cell, any cell... p490
Can an adult human cell be turned back to an embryonic state without the need for cloning? If so, ethical objections to personalized regenerative medicine would be swept away. Carina Dennis reports.
doi:10.1038/426490a
Ocean drilling: Digging in p492
A new ship and a wave of funding will let scientists drill where they have never been able to drill before, from near the North Pole to the rocks lying beneath Earth's crust. Rex Dalton and David Cyranoski report.
doi:10.1038/426492a
Correspondence
Is science losing out in the race for recognition? p495
Progress is made through the achievements of many who are not singled out for reward.
Robert Marc Friedman
doi:10.1038/426495a
GM-debate methodology works in the real world p495
Robin Grove-White
doi:10.1038/426495b
Citation rate unrelated to journals' impact factors p495
A. A. Waheed
doi:10.1038/426495c
Books and Arts
The search for Enlightenment p497
Roy Porter's last book examines eighteenth-century morals and mores.
Patricia Fara reviews Flesh in the Age of Reason by Roy Porter
doi:10.1038/426497a
A base in space p498
Asif A. Siddiqi reviews Leaving Earth: Space Stations, Rival Superpowers, and the Quest for Interplanetary Travel by Robert Zimmerman
doi:10.1038/426498a
Website: Tempting teens with love in the lab p499
Carina Dennis reviews Planet Jemma
doi:10.1038/426499a
New in paperback p499
doi:10.1038/426499b
Lifelines
Joan Slonczewski: Stranger than fiction p501
Joan Slonczewski is a microbiologist at Kenyon College in Gambier, Ohio, and is also an acclaimed writer of science fiction (seeNature405, 1001; 2000). Her novels include Brain Plague and A Door into Ocean.
doi:10.1038/426501a
News and Views
Developmental biology: Long-range signalling by touch p503
In the developing sense organs of fruitflies, cells must signal instructions over long distances. But the signalling molecule is bound to the cell membrane, so how can it reach its targets? The answer, it seems, is by touch.
Stephen M. Cohen
doi:10.1038/426503a
Astrophysics: Testing time for gravity p504
The discovery of two neutron stars tightly orbiting each other suggests that the rate of neutron-star mergers in the Universe is higher than had been thought — which is good news for seekers of gravitational waves.
E. P. J. van den Heuvel
doi:10.1038/426504a
100 and 50 years ago p504
doi:10.1038/426504b
Membrane trafficking: Coat control by curvature p507
The main transport vehicles inside cells are spherical vesicles that form when patches of membrane curve into buds and then pinch off. 'Coat' proteins both control, and are controlled by, this membrane curvature.
Jennifer Lippincott-Schwartz and Wei Liu
doi:10.1038/426507a
Chemistry: Internal combustion p508
It's sometimes difficult to observe combustion in situ — inside, say, a porous material or an industrial reactor. But with the help of nuclear magnetic resonance, a new vista has opened up.
Jeffrey Reimer
doi:10.1038/426508a
Mammalian evolution: Isolationist tendencies p509
For some 40 million years, the Afro-Arabian landmass existed in splendid isolation. A newly described fossil fauna from the end of that time provides a window on the evolution of the continent's large mammals.
Jean-Jacques Jaeger
doi:10.1038/426509a
Condensed-matter physics: Illuminating behaviour p511
In fewer than three dimensions, the behaviour of electrons in metals should change to that of a 'Tomonaga–Luttinger liquid'. A photoemission study of one-dimensional carbon nanotubes supports this prediction.
Marc Bockrath
doi:10.1038/426511a
Medicine: Taking apart a cancer protein p512
Generation of a particular 'fusion' protein is characteristic of one type of leukaemia. But is it in fact the cleavage of this protein into smaller parts that is important? Provocative new findings suggest that it is.
Pier Paolo Scaglioni and Pier Paolo Pandolfi
doi:10.1038/426512a
News and views in brief p514
doi:10.1038/426514a
Brief Communications
On-chip manipulation of free droplets p515
Tiny free-floating drops can be driven across a liquid medium by an electric field.
Orlin D. Velev, Brian G. Prevo and Ketan H. Bhatt
doi:10.1038/426515a
First paragraph | Full Text | PDF (172K) | Supplementary information
Palaeontology: A polydactylous amniote from the Triassic period p516
Xiao-Chun Wu, Zhan Li, Bao-Chun Zhou and Zhi-Ming Dong
doi:10.1038/426516a
First paragraph | Full Text | PDF (88K) | Supplementary information
Review
TRP channels as cellular sensors p517
David E. Clapham
doi:10.1038/nature02196
Abstract | Full Text | PDF (394K)
Article
Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor p525
Louis Renault, Bernard Guibert and Jacqueline Cherfils
doi:10.1038/nature02197
Abstract | Full Text | PDF (320K) | Supplementary information
Letters to Nature
An increased estimate of the merger rate of double neutron stars from observations of a highly relativistic system p531
M. Burgay, N. D'Amico, A. Possenti, R. N. Manchester, A. G. Lyne, B. C. Joshi, M. A. McLaughlin, M. Kramer, J. M. Sarkissian, F. Camilo, V. Kalogera, C. Kim and D. R. Lorimer
doi:10.1038/nature02124
First paragraph | Full Text | PDF (211K)
See also: News and Views by van den Heuvel
Continuous magnetic reconnection at Earth's magnetopause p533
H. U. Frey, T. D. Phan, S. A. Fuselier and S. B. Mende
doi:10.1038/nature02084
First paragraph | Full Text | PDF (369K)
Emergence of a molecular Bose–Einstein condensate from a Fermi gas p537
Markus Greiner, Cindy A. Regal and Deborah S. Jin
doi:10.1038/nature02199
First paragraph | Full Text | PDF (218K)
Direct observation of Tomonaga–Luttinger-liquid state in carbon nanotubes at low temperatures p540
Hiroyoshi Ishii, Hiromichi Kataura, Hidetsugu Shiozawa, Hideo Yoshioka, Hideo Otsubo, Yasuhiro Takayama, Tsuneaki Miyahara, Shinzo Suzuki, Yohji Achiba, Masashi Nakatake, Takamasa Narimura, Mitsuharu Higashiguchi, Kenya Shimada, Hirofumi Namatame and Masaki Taniguchi
doi:10.1038/nature02074
First paragraph | Full Text | PDF (658K)
See also: News and Views by Bockrath
Migration of seismic scatterers associated with the 1993 Parkfield aseismic transient event p544
Fenglin Niu, Paul G. Silver, Robert M. Nadeau and Thomas V. McEvilly
doi:10.1038/nature02151
First paragraph | Full Text | PDF (943K)
Oligocene mammals from Ethiopia and faunal exchange between Afro-Arabia and Eurasia p549
John Kappelman, D. Tab Rasmussen, William J. Sanders, Mulugeta Feseha, Thomas Bown, Peter Copeland, Jeff Crabaugh, John Fleagle, Michelle Glantz, Adam Gordon, Bonnie Jacobs, Murat Maga, Kathleen Muldoon, Aaron Pan, Lydia Pyne, Brian Richmond, Timothy Ryan, Erik R. Seiffert, Sevket Sen, Lawrence Todd, Michael C. Wiemann and Alisa Winkler
doi:10.1038/nature02102
First paragraph | Full Text | PDF (388K) | Supplementary information
See also: News and Views by Jaeger
Ocean currents mediate evolution in island lizards p552
Ryan Calsbeek and Thomas B. Smith
doi:10.1038/nature02143
First paragraph | Full Text | PDF (195K)
Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila p555
Cyrille de Joussineau, Jonathan Soulé, Marianne Martin, Christelle Anguille, Philippe Montcourrier and Daniel Alexandre
doi:10.1038/nature02157
First paragraph | Full Text | PDF (470K)
See also: News and Views by Cohen
Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo p559
Kira E. Poskanzer, Kurt W. Marek, Sean T. Sweeney and Graeme W. Davis
doi:10.1038/nature02184
First paragraph | Full Text | PDF (426K) | Supplementary information
Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature p563
Joëlle Bigay, Pierre Gounon, Sylviane Robineau and Bruno Antonny
doi:10.1038/nature02108
First paragraph | Full Text | PDF (323K) | Supplementary information
See also: News and Views by Lippincott-Schwartz & Liu
Targeted degradation of TOC1 by ZTL modulates circadian function in Arabidopsis thaliana p567
Paloma Más, Woe-Yeon Kim, David E. Somers and Steve A. Kay
doi:10.1038/nature02163
First paragraph | Full Text | PDF (356K) | Supplementary information
Proteomic characterization of the human centrosome by protein correlation profiling p570
Jens S. Andersen, Christopher J. Wilkinson, Thibault Mayor, Peter Mortensen, Erich A. Nigg and Matthias Mann
doi:10.1038/nature02166
First paragraph | Full Text | PDF (307K) | Supplementary information
Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2 p574
Kristina Lorenz, Martin J. Lohse and Ursula Quitterer
doi:10.1038/nature02158
First paragraph | Full Text | PDF (419K) | Supplementary information
Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly p579
Marcello Ceci, Cristina Gaviraghi, Chiara Gorrini, Leonardo A. Sala, Nina Offenhäuser, Pier Carlo Marchisio and Stefano Biffo
doi:10.1038/nature02160
First paragraph | Full Text | PDF (312K) | Supplementary information
Corrigendum: Cyanophages infecting the oceanic cyanobacterium Prochlorococcus p584
Matthew B. Sullivan, John B. Waterbury and Sallie W. Chisholm
doi:10.1038/nature02147
Corrigendum: Sustained division of the attentional spotlight p584
M. M. Müller, P. Malinowski, T. Gruber and S. A. Hillyard
doi:10.1038/nature02148
Corrigendum: Cdc6 cooperates with Sic1 and Hct1 to inactivate mitotic cyclin-dependent kinases p584
Arturo Calzada, Maria Sacristán, Elisa Sánchez and Avelino Bueno
doi:10.1038/nature02154
Corrigendum: Zero thermal expansion in YbGaGe due to an electronic valence transition p584
James R. Salvador, Fu Guo, Tim Hogan and Mercouri G. Kanatzidis
doi:10.1038/nature02182
Corrigendum: Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)K
p584
Takehiko Sasaki, Junko Irie-Sasaki, Yasuo Horie, Kurt Bachmaier, Jimmie E. Fata, Martin Li, Akira Suzuki, Dennis Bouchard, Alexandra Ho, Mark Redston, Steven Gallinger, Rama Khokha, Tak W. Mak, Phillip T. Hawkins, Len Stephens, Stephen W. Scherer, Ming Tsao and Josef M. Penninger
doi:10.1038/nature02203
New on the Market
Go for the soft cell p585
For cell biologists and those with similar callings.
doi:10.1038/426585a
Naturejobs
ProspectsMaking choices p587
Paul Smaglik
doi:10.1038/nj6966-587a
Career View
Young Scientist: Women mentoring women p588
Helen McBride
doi:10.1038/nj6966-588a
Nuts & Bolts p588
Deb Koen
doi:10.1038/nj6966-588b
Movers p588
doi:10.1038/nj6966-588c
