Table of contents
Volume 425 Number 6956 pp329-433
Editorial
Dealing with democracy p329
The drive for greater public participation in the regulation and politics of technologies is both necessary and irreversible. But proposals to extend it into the selection of publicly funded research contain dangers to science and society.
doi:10.1038/425329a
News
Gates steps up war on malaria with donation of $168 million p331
Declan Butler
doi:10.1038/425331a
UK public opposes government on transgenic crops p331
Jim Giles
doi:10.1038/425331b
Report raises hopes for grand network of US ecology centres p332
Rex Dalton
doi:10.1038/425332a
Vaccine claim lifts company's stock but angers researchers p332
Erika Check
doi:10.1038/425332b
SARS triggers biomedical shake-up in China p333
David Cyranoski
doi:10.1038/425333a
Secret garden opens up to public p333
David Cyranoski
doi:10.1038/425333b
Open-access row leads paper to shed authors p334
Declan Butler
doi:10.1038/425334a
Cosmologists cluster to plot course towards dark energy p335
Geoff Brumfiel
doi:10.1038/425335a
DNA lab welcomes Dalai Lama to Tibetan science community p335
Erika Check
doi:10.1038/425335b
News Features
Alaska's climate: Too hot to handle p338
Alaska is warming up more than anywhere else on Earth. Climate researchers are now turning to regional models to find out why — and how to deal with it. John Whitfield went north to investigate.
doi:10.1038/425338a
Dyslexia: Lost for words p340
Thanks in part to brain-imaging technology, researchers are now homing in on the root cause of dyslexia. But research into strategies for treating the condition is still in its infancy, says Glenn Murphy.
doi:10.1038/425340a
Correspondence
Global project needed to tackle coffee crisis p343
A sharp drop in coffee prices has caused widespread suffering and hindered research.
Fernando E. Vega, Eric Rosenquist and Wanda Collins
doi:10.1038/425343a
The public has its own view of what is a risk p343
Emmanuelle Schuler
doi:10.1038/425343b
Feynman put a personal spin on physics p343
R. W. D. Nickalls
doi:10.1038/425343c
Books and Arts
Learning to evolve p345
A fresh look at whether learning alters the course of natural selection.
Kevin N. Laland reviews Evolution and Learning: The Baldwin Effect Reconsidered
doi:10.1038/425345a
Biologists become clock-watchers p346
John Palmer reviews Chronobiology: Biological Timekeeping
doi:10.1038/425346a
A dangerous world? p346
Roger Cox reviews The Suffering Gene: Environmental Threats to our Health by Roy Burdon
doi:10.1038/425346b
Exhibition: Unnatural causes p347
Alison Abbott
doi:10.1038/425347a
Reissued classics p347
doi:10.1038/425347b
Lifelines
Roberto Macchiarelli: The whole tooth p349
Roberto Macchiarelli is a palaeoanthropologist. Until recently at the National Museum of Prehistory and Ethnography in Rome, he is currently professor of human palaeontology at the University of Poitiers, France.
doi:10.1038/425349a
News and Views
Immunology: Professional secrets p351
Looking inside the compartments of certain immune cells — professional antigen-presenting cells — has revealed how the immune system can trigger a cell-killing response to extracellular pathogens.
Craig R. Roy
doi:10.1038/425351a
Plasma physics: Cosmic waves in the lab p352
An Alfvén-wave maser, a feature of atmospheric and astrophysical science, has been created in a laboratory, and opens the way for further Earth-bound investigations of cosmic phenomena.
Rod Boswell
doi:10.1038/425352a
Stem cells: To be and not to be p353
It has long been proposed that stem cells function by dividing to generate an identical daughter cell and a cell that becomes more specialized. New work illustrates such asymmetric division and its molecular basis.
Haifan Lin
doi:10.1038/425353a
100 and 50 years ago p356
doi:10.1038/425356a
Synthetic chemistry: Ship reverses out of bottle p356
The industrial application of zeolites is limited by the cost of certain organic materials that are needed to make them, but which are destroyed in the process. A clever technique offers a solution.
Avelino Corma
doi:10.1038/425356b
Cancer: The rules of attraction p357
The puzzle of how a drug that binds to a protein found in normal cells as well as cancer cells preferentially kills tumours is now solved — the target protein exists in a drug-binding complex in tumour cells.
Len Neckers and Yong-Sok Lee
doi:10.1038/425357a
Applied physics: Spintronics gets a magnetic flute p359
Magnetic-memory devices of the future could be based on 'spintronics', through switching the directions of electron spins. New work confirms the physics behind a spin-switching mechanism.
Jonathan Sun
doi:10.1038/425359a
Zoology: Light touch on the rudder p360
Tim Lincoln
doi:10.1038/425360a
Plant biology: Water gate p361
Flooding reduces the ability of roots to absorb water. The molecular basis for this paradox involves the regulation of water-channel proteins by the pH inside root cells.
N. Michele Holbrook and Maciej A. Zwieniecki
doi:10.1038/425361a
Obituary: Edward Teller (1908–2003) p362
John Maddox
doi:10.1038/425362a
News and views in brief p364
doi:10.1038/425364a
Brief Communications
Oceanography: Anthropogenic carbon and ocean pH p365
The coming centuries may see more ocean acidification than the past 300 million years.
Ken Caldeira and Michael E. Wickett
doi:10.1038/425365a
First paragraph | Full Text | PDF (120K)
Archaeology: Sharp shift in diet at onset of Neolithic p366
Michael P. Richards, Rick J. Schulting and Robert E. M. Hedges
doi:10.1038/425366a
First paragraph | Full Text | PDF (64K)
Corrigendum: Insecticide resistance in mosquito vectors p366
doi:10.1038/425366b
Article
Bending-related faulting and mantle serpentinization at the Middle America trench p367
C. R. Ranero, J. Phipps Morgan, K. McIntosh and C. Reichert
doi:10.1038/nature01961
Abstract | Full Text | PDF (892K)
Letters to Nature
A test of general relativity using radio links with the Cassini spacecraft p374
B. Bertotti, L. Iess and P. Tortora
doi:10.1038/nature01997
First paragraph | Full Text | PDF (194K) | Supplementary information
Uniform resonant chaotic mixing in fluid flows p376
T. H. Solomon
and
Igor Mezi
doi:10.1038/nature01993
First paragraph | Full Text | PDF (484K) | Supplementary information
Microwave oscillations of a nanomagnet driven by a spin-polarized current p380
S. I. Kiselev, J. C. Sankey, I. N. Krivorotov, N. C. Emley, R. J. Schoelkopf, R. A. Buhrman and D. C. Ralph
doi:10.1038/nature01967
First paragraph | Full Text | PDF (394K)
See also: News and Views by Sun
Video-speed electronic paper based on electrowetting p383
Robert A. Hayes and B. J. Feenstra
doi:10.1038/nature01988
First paragraph | Full Text | PDF (211K) | Supplementary information
A combustion-free methodology for synthesizing zeolites and zeolite-like materials p385
Hyunjoo Lee, Stacey I. Zones and Mark E. Davis
doi:10.1038/nature01980
First paragraph | Full Text | PDF (256K) | Supplementary information
See also: News and Views by Corma
An Arctic mammal fauna from the Early Pliocene of North America p388
Richard H. Tedford and C. Richard Harington
doi:10.1038/nature01892
First paragraph | Full Text | PDF (202K)
Volunteering leads to rock–paper–scissors dynamics in a public goods game p390
Dirk Semmann, Hans-Jürgen Krambeck and Manfred Milinski
doi:10.1038/nature01986
First paragraph | Full Text | PDF (193K)
Cytosolic pH regulates root water transport during anoxic stress through gating of aquaporins p393
Colette Tournaire-Roux, Moira Sutka, Hélène Javot, Elisabeth Gout, Patricia Gerbeau, Doan-Trung Luu, Richard Bligny and Christophe Maurel
doi:10.1038/nature01853
First paragraph | Full Text | PDF (287K) | Supplementary information
See also: News and Views by Holbrook & Zwieniecki
ER–phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells p397
Pierre Guermonprez, Loredana Saveanu, Monique Kleijmeer, Jean Davoust, Peter van Endert and Sebastian Amigorena
doi:10.1038/nature01911
First paragraph | Full Text | PDF (533K) | Supplementary information
Phagosomes are competent organelles for antigen cross-presentation p402
Mathieu Houde, Sylvie Bertholet, Etienne Gagnon, Sylvain Brunet, Guillaume Goyette, Annie Laplante, Michael F. Princiotta, Pierre Thibault, David Sacks and Michel Desjardins
doi:10.1038/nature01912
First paragraph | Full Text | PDF (573K) | Supplementary information
See also: News and Views by Roy
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors p407
Adeela Kamal, Lia Thao, John Sensintaffar, Lin Zhang, Marcus F. Boehm, Lawrence C. Fritz and Francis J. Burrows
doi:10.1038/nature01913
First paragraph | Full Text | PDF (352K) | Supplementary information
See also: News and Views by Neckers & Lee
A micrococcal nuclease homologue in RNAi effector complexes p411
Amy A. Caudy, René F. Ketting, Scott M. Hammond, Ahmet M. Denli, Anja M. P. Bathoorn, Bastiaan B. J. Tops, Jose M. Silva, Mike M. Myers, Gregory J. Hannon and Ronald H. A. Plasterk
doi:10.1038/nature01956
First paragraph | Full Text | PDF (317K) | Supplementary information
The nuclear RNase III Drosha initiates microRNA processing p415
Yoontae Lee, Chiyoung Ahn, Jinju Han, Hyounjeong Choi, Jaekwang Kim, Jeongbin Yim, Junho Lee, Patrick Provost, Olof Rådmark, Sunyoung Kim and V. Narry Kim
doi:10.1038/nature01957
First paragraph | Full Text | PDF (480K) | Supplementary information
A structural state of the myosin V motor without bound nucleotide p419
Pierre-Damien Coureux, Amber L. Wells, Julie Ménétrey, Christopher M. Yengo, Carl A. Morris, H. Lee Sweeney and Anne Houdusse
doi:10.1038/nature01927
First paragraph | Full Text | PDF (399K) | Supplementary information
Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide p423
Kenneth C. Holmes, Isabel Angert, F. Jon Kull, Werner Jahn and Rasmus R. Schröder
doi:10.1038/nature02005
First paragraph | Full Text | PDF (417K) | Supplementary information
Naturejobs
ProspectsTrue grit p429
Paul Smaglik
doi:10.1038/nj6956-429a
REGIONS
Northern England: Rising star p430
Paul Smaglik
doi:10.1038/nj6956-430a
