Table of contents
Volume 422 Number 6933 pp647-785
Editorials
Reining in assisted reproduction p647
Fears about the safety of reproductive technologies should be kept in perspective, but more research is needed to assess the risks. In the meantime, its practitioners should learn the virtue of caution.
doi:10.1038/422647a
Anything you can do... p647
Spy scandals notwithstanding, the party goes on at the two US nuclear-weapons design labs — and so does the backbiting.
doi:10.1038/422647b
News
Flight records reveal full extent of Agent Orange contamination p649
Declan Butler
doi:10.1038/422649a
Trial suggests vaccines could aid HIV therapy p650
Erika Check
doi:10.1038/422650a
Chemists' salaries turn south p650
Hannah Hoag
doi:10.1038/422650b
Livermore official linked with alleged spy p651
Geoff Brumfiel
doi:10.1038/422651a
Partners dig deep for ocean-drilling project p651
Geoff Brumfiel
doi:10.1038/422651b
Taiwan left isolated in fight against SARS p652
David Cyranoski
doi:10.1038/422652a
Infection risk puts the brakes on Canada's biomedical research p652
Tom Clarke
doi:10.1038/422652b
NASA homes in on sites for Mars exploration p653
Tony Reichhardt
doi:10.1038/422653a
Polish science academy prepares for radical overhaul p653
Quirin Schiermeier
doi:10.1038/422653b
news feature
Fertility treatments: Seeds of doubt p656
Questions are now being asked about the safety of some of the techniques used to overcome human infertility. Kendall Powell examines whether the health of test-tube babies is at risk.
Kendall Powell
doi:10.1038/422656a
Planet formation: Worlds apart p659
Our knowledge of planets outside our Solar System has been transformed in the past few years. But these new-found worlds don't look much like our planetary neighbours, and no one is quite sure why. Dan Falk investigates.
Dan Falk
doi:10.1038/422659a
Correspondence
Progressing towards a biological names register p661
How taxonomy could harness the indexing and organizational powers of the Internet.
David J. Patterson
doi:10.1038/422661a
Peer review and the rewards of open access p661
Peter Newmark
doi:10.1038/422661b
Books and Arts
Out, out, brief candle? p663
Time is slowly running out for life on Earth.
Norman H. Sleep reviews Impossible Extinction: Natural Catastrophes and the Supremacy of the Microbial World by Charles C. Cockell and The Life and Death of Planet Earth: How the New Science of Astrobiology Charts the Ultimate Fate of our World by Peter D. Ward and Donald Brownlee
doi:10.1038/422663a
A stratospheric success p664
Charles Herrick reviews Protecting the Ozone Layer: Science and Strategy by Edward A. Parson and Protecting the Ozone Layer: The United Nations History by S. O. Anderson and K. M. Sarma
doi:10.1038/422664a
Getting up to speed p665
Stephen Gatesy reviews Principles of Animal Locomotion by R. McNeill Alexander
doi:10.1038/422665a
Standing the test of time p665
doi:10.1038/422665b
Science in culture p666
Martin Kemp reviews
doi:10.1038/422666a
concepts
Archaeological verification: Puzzling out the past p667
Robert Hedges
doi:10.1038/422667a
News and Views
Animal behaviour: Wise fathers p669
As Shakespeare put it, "It is a wise father that knows his own child". Male bluegill sunfish do: they adjust their behaviour towards their young according to how sure they are of being the real father.
John D. Reynolds and Ben C. Sheldon
doi:10.1038/422669a
Astronomy: Wrestling monsters in deep space p670
Observing distant galaxies is always problematic. But when it comes to the biggest star-forming galaxies, far across the Universe, only indirect approaches can give astronomers any handle at all.
Lennox Cowie
doi:10.1038/422670a
Medicine: Collateral damage repaired p671
Multiple sclerosis is characterized by immunological attacks across a wide front in the brain and spinal cord. In mice, the damage can be partly repaired by neural precursor cells, delivered into the blood or spinal fluid.
Lawrence Steinman
doi:10.1038/422671a
Plant biology: Mutual sanctions p672
The bacterium-filled nodules found on legumes represent a mutually beneficial arrangement. But it is evidently one with sophisticated checks and balances to ensure a fair deal for both partners in the marriage.
Janet Sprent
doi:10.1038/422672a
100 and 50 years ago p673
doi:10.1038/422673a
Earth science: Roots of the matter p674
How far down does the ancient continental material that constitutes Earth's 'tectosphere' extend? Fresh interpretation of the behaviour of seismic waves helps in reconciling previous estimates.
B. L. N. Kennett
doi:10.1038/422674a
Materials science: Mind the graphite gap p674
Jane Morris
doi:10.1038/422674b
Immunology: Oxygen and the inflammatory cell p675
The discovery that a single protein allows certain immune cells both to respond to low oxygen levels and to induce inflammation may provide a new target for drugs to treat diseases characterized by excessive inflammation.
Carl Nathan
doi:10.1038/422675a
news and views in brief p677
doi:10.1038/422677a
Brief Communications
Epidemiology: Sexual transmission of HIV in Africa p679
Other routes of infection are not the dominant contributor to the African epidemic.
Polly R. Walker, Michael Worobey, Andrew Rambaut, Edward C. Holmes and Oliver G. Pybus
doi:10.1038/422679a
First paragraph | Full Text | PDF (81K) | Supplementary information
Space travel: Dual origins of light flashes seen in space p680
M. Casolino, V. Bidoli, A. Morselli, L. Narici, M. P. De Pascale, P. Picozza, E. Reali, R. Sparvoli, G. Mazzenga, M. Ricci, P. Spillantini, M. Boezio, V. Bonvicini, A. Vacchi, N. Zampa, G. Castellini, W. G. Sannita, P. Carlson, A. Galper, M. Korotkov, A. Popov, N. Vavilov, S. Avdeev and C. Fuglesang
doi:10.1038/422680a
First paragraph | Full Text | PDF (69K)
Articles
The extent and patterns of usage of Agent Orange and other herbicides in Vietnam p681
Jeanne Mager Stellman, Steven D. Stellman, Richard Christian, Tracy Weber and Carrie Tomasallo
doi:10.1038/nature01537
Abstract | Full Text | PDF (441K)
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis p688
Stefano Pluchino, Angelo Quattrini, Elena Brambilla, Angela Gritti, Giuliana Salani, Giorgia Dina, Rossella Galli, Ubaldo Del Carro, Stefano Amadio, Alessandra Bergami, Roberto Furlan, Giancarlo Comi, Angelo L. Vescovi and Gianvito Martino
doi:10.1038/nature01552
Abstract | Full Text | PDF (676K) | Supplementary information
See also: News and Views by Steinman
Letters to Nature
A median redshift of 2.4 for galaxies bright at submillimetre wavelengths p695
S. C. Chapman, A. W. Blain, R. J. Ivison and Ian R. Smail
doi:10.1038/nature01540
First paragraph | Full Text | PDF (469K)
See also: News and Views by Cowie
An inverse transition of magnetic domain patterns in ultrathin films p701
O. Portmann, A. Vaterlaus and D. Pescia
doi:10.1038/nature01538
First paragraph | Full Text | PDF (621K)
Dissociative hydrogen adsorption on palladium requires aggregates of three or more vacancies p705
T. Mitsui, M. K. Rose, E. Fomin, D. F. Ogletree and M. Salmeron
doi:10.1038/nature01557
First paragraph | Full Text | PDF (2,181K) | Supplementary information
Global anisotropy and the thickness of continents p707
Yuancheng Gung, Mark Panning and Barbara Romanowicz
doi:10.1038/nature01559
First paragraph | Full Text | PDF (1,439K) | Supplementary information
Soil invertebrate fauna enhances grassland succession and diversity p711
Gerlinde B. De Deyn, Ciska E. Raaijmakers, H. Rik Zoomer, Matty P. Berg, Peter C. de Ruiter, Herman A. Verhoef, T. Martijn Bezemer and Wim H. van der Putten
doi:10.1038/nature01548
First paragraph | Full Text | PDF (176K)
Explaining the excess of rare species in natural species abundance distributions p714
Anne E. Magurran and Peter A. Henderson
doi:10.1038/nature01547
First paragraph | Full Text | PDF (176K)
Decisions about parental care in response to perceived paternity p716
Bryan D. Neff
doi:10.1038/nature01528
First paragraph | Full Text | PDF (190K)
See also: News and Views by Reynolds & Sheldon
Adaptation of photoperiodic control pathways produces short-day flowering in rice p719
Ryosuke Hayama, Shuji Yokoi, Shojiro Tamaki, Masahiro Yano and Ko Shimamoto
doi:10.1038/nature01549
First paragraph | Full Text | PDF (351K) | Supplementary information
Amino-acid cycling drives nitrogen fixation in the legume–Rhizobium symbiosis p722
E. M. Lodwig, A. H. F. Hosie, A. Bourdès, K. Findlay, D. Allaway, R. Karunakaran, J. A. Downie and P. S. Poole
doi:10.1038/nature01527
First paragraph | Full Text | PDF (384K)
See also: News and Views by Sprent
Transcription-targeted DNA deamination by the AID antibody diversification enzyme p726
Jayanta Chaudhuri, Ming Tian, Chan Khuong, Katrin Chua, Eric Pinaud and Frederick W. Alt
doi:10.1038/nature01574
First paragraph | Full Text | PDF (347K)
Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2 p730
Aidong Han, Fan Pan, James C. Stroud, Hong-Duk Youn, Jun O. Liu and Lin Chen
doi:10.1038/nature01555
First paragraph | Full Text | PDF (462K) | Supplementary information
Coordinated histone modifications mediated by a CtBP co-repressor complex p735
Yujiang Shi, Jun-ichi Sawada, Guangchao Sui, El Bachir Affar, Johnathan R. Whetstine, Fei Lan, Hidesato Ogawa, Margaret Po-Shan Luke, Yoshihiro Nakatani and Yang Shi
doi:10.1038/nature01550
First paragraph | Full Text | PDF (374K) | Supplementary information
insight
introductioncytoskeleton p739
Deepa Nath
doi:10.1038/422739a
overview
The cytoskeleton, cellular motility and the reductionist agenda p741
Thomas D. Pollard
doi:10.1038/nature01598
Abstract | Full Text | PDF (341K)
review article
Cell division p746
Jonathan M. Scholey, Ingrid Brust-Mascher and Alex Mogilner
doi:10.1038/nature01599
Abstract | Full Text | PDF (601K)
Dynamics and mechanics of the microtubule plus end p753
Joe Howard and Anthony A. Hyman
doi:10.1038/nature01600
Abstract | Full Text | PDF (976K)
Molecular motors p759
Manfred Schliwa and Günther Woehlke
doi:10.1038/nature01601
Abstract | Full Text | PDF (418K)
Adaptation of core mechanisms to generate cell polarity p766
W. James Nelson
doi:10.1038/nature01602
Abstract | Full Text | PDF (3,438K)
Microbial pathogenesis and cytoskeletal function p775
Samantha Gruenheid and B. Brett Finlay
doi:10.1038/nature01603
Abstract | Full Text | PDF (1,374K)
corporate support
Leading the way to the next generation of anti-mitotics p781
Kenneth W. Wood, Ph.D., Jeffrey R. Jackson, Ph.D., David J. Morgans, Jr., Ph.D., John D. Elliott, Ph.D., James H. Sabry, M.D. Ph.D. and Pearl S. Huang, Ph.D.
doi:10.1038/422781a
About Cytokinetics p782
doi:10.1038/422782a
About GlaxoSmithKline p783
doi:10.1038/422783a
Naturejobs
ProspectsSalary isn't everything p783
Paul Smaglik
doi:10.1038/nj6933-783a
POSTDOCS
Stacking the deck p784
Without doing the homework, choosing a postdoc position is a bit like picking a playing card at random. Karen Kreeger advises on how to come up trumps.
Karen Kreeger
doi:10.1038/nj6933-784a
