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Editorials

Time to unite Islam and science p99

Science in Muslim countries is weak. The reasons for this deserve attention, as do the consequences for these nations' economic health. A meeting last week provided a start in this direction.

doi:10.1038/422099a


A little protectionism goes a long way p99

China's stalling on introducing transgenic crops may frustrate outsiders, but helps it nurture its own biotechnology industry.

doi:10.1038/422099b


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News

Academies wrestle with issue of Islam's flagging science base p101

Declan Butler

doi:10.1038/422101a


Bush seeks to beef up US nuclear-weapons arsenal p101

Geoff Brumfiel

doi:10.1038/422101b


Biotech project in turmoil as Michigan balances books p102

Jonathan Knight

doi:10.1038/422102a


Auction of DNA archive cancelled p102

Rex Dalton

doi:10.1038/422102b


Senator rebuffs academy over Arctic oil p103

Tony Reichhardt

doi:10.1038/422103a


Tougher rules aim to prevent gene flow into crops p103

Hannah Hoag

doi:10.1038/422103b


Hydrogen cars fuel debate on basic research p104

Geoff Brumfiel

doi:10.1038/422104a


Russia pulls out of Antarctic station p104

Bryon MacWilliams

doi:10.1038/422104b


Max Planck plans double blow to chemistry p105

Quirin Schiermeier

doi:10.1038/422105a


Danish biotech centre faces axe p105

Alison Abbott

doi:10.1038/422105b


news in brief p106

doi:10.1038/422106a


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news feature

Cosmology gets real p108

By clarifying the age and make-up of the Universe, researchers have ushered in an era of precision cosmology. Now they are preparing to probe the mysteries of dark matter and dark energy. Geoff Brumfiel reports.

Geoff Brumfiel

doi:10.1038/422108a


Chinese agribiotech: Against the grain p111

China has long been a keen supporter of transgenic agriculture, and is still pouring money into developing the technology. So why are applications to market new genetically modified crops in limbo? Colin Macilwain investigates.

Colin Macilwain

doi:10.1038/422111a


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Correspondence

Work on 'non-lethal' weapons should be limited too p113

Security fears have led to violation of international law before. It must not happen again.

Jerome Amir Singh

doi:10.1038/422113a


Universities could gain from backing biotech p113

Alexander Kamb

doi:10.1038/422113b


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Commentary

Constellations in a cellular universe p115

We must agree now on strategies to search the proteome.

doi:10.1038/422115a


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Book Reviews

Move to the rhythm p117

Many systems, from pendulums to fireflies, work in synchrony.

J. J. Collins reviews Sync: The Emerging Science of Spontaneous Order by Steven Strogatz

doi:10.1038/422117a


All in the mind? p118

Walter A. Brown reviews Placebo: The Belief Effect by Dylan Evans

doi:10.1038/422118a


Through the eye of the lynx p118

doi:10.1038/422118b


First among atoms p119

Daniel Kleppner reviews Hydrogen: The Essential Element by John S. Rigden

doi:10.1038/422119a


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Lifeline

Behind the blooms: David Smyth p121

doi:10.1038/422121a


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concepts

Hormone evolution: The key to signalling p122

Tetsuo Kushiro, Eiji Nambara and Peter McCourt

doi:10.1038/422122a


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News and Views

Developmental biology: Flowers' wings, fruitflies' petals p123

The technique of clonal analysis allows dividing cells in a developing organ to be marked and tracked. The aim of such studies, in plants as well as animals, is to understand how tissues acquire their form and size.

Claude Desplan and Thomas Lecuit

doi:10.1038/422123a


Astronomy: Atmosphere out of that world p124

A planet orbiting very close to a Sun-like star is apparently enveloped by an extended atmosphere of hydrogen atoms, and may be losing mass because of the intense radiation from the parent star.

David Charbonneau

doi:10.1038/422124a


Developmental biology: Guidance molecule goes global p125

Alison Schuldt

doi:10.1038/422125a


Behavioural science: Fair's fair p125

A basic theory of behaviour holds that people act only in their own best interests. But more complex motives are apparent in an experimental study that shows that generosity is diminished by the unfairness of others.

Truman Bewley

doi:10.1038/422125b


Planetary science: The core of planet formation p126

The rocky bodies from which the Earth formed may have already separated into a metal core and silicate shell. Innovative experiments exploring the behaviour of molten metal trapped between silicate grains suggest how.

Bill Minarik

doi:10.1038/422126a


100 and 50 years ago p127

doi:10.1038/422127a


Evolutionary biology: Teeth as tools p128

What determines the shapes of mammalian teeth? When tools are designed to cut to the meat of the question, form follows function rather than developmental or evolutionary constraints.

Anne Weil

doi:10.1038/422128a


Surface science: View from the edge p129

Bombarding a material with an ion beam provides valuable information about its surface composition. Ion guns that fire polyatomic ions can reveal more detailed information and cause less damage to the sample.

David G. Castner

doi:10.1038/422129a


Medicine: Smoke signals for lung disease p130

A group of proteins that might confer susceptibility to emphysema has been identified. One of them is transforming growth factor-beta, and the discovery highlights the many ways of activating this protein in health and disease.

Anita B. Roberts

doi:10.1038/422130a


Solar System: Close encounter of the cometary kind p130

Alison Wright

doi:10.1038/422130b


news and views in brief p132

doi:10.1038/422132a


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Brief Communications

Palaeontology: Human footprints in Pleistocene volcanic ash p133

These ancient tracks are the oldest known to have been made by fully bipedal humans.

Paolo Mietto, Marco Avanzini and Giuseppe Rolandi

doi:10.1038/422133a


Atmospheric science: Ultraviolet light and leaf emission of NOx p134

Pertti Hari, Maarit Raivonen, Timo Vesala, J. William Munger, Kim Pilegaard and Markku Kulmala

doi:10.1038/422134a


Conservation: Reproductive collapse in saiga antelope harems p135

E. J. Milner-Gulland, O. M. Bukreeva, T. Coulson, A. A. Lushchekina, M. V. Kholodova, A. B. Bekenov and I. A. Grachev

doi:10.1038/422135a


Earth science (Communication arising): Mantle deformation or processing artefact? p136

Joachim Saul and Lev Vinnik

doi:10.1038/422136a


Earth science (Communication arising (Reply)): Mantle deformation or processing artefact? p136

James Wookey, J.-Michael Kendall and Guilhem Barruol

doi:10.1038/422136b


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Article

Detrimental effects of sanctions on human altruism p137

Ernst Fehr and Bettina Rockenbach

doi:10.1038/nature01474

See also: News and Views by Bewley


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Letters to Nature

Nanosecond radio bursts from strong plasma turbulence in the Crab pulsar p141

T. H. Hankins, J. S. Kern, J. C. Weatherall and J. A. Eilek

doi:10.1038/nature01477


An extended upper atmosphere around the extrasolar planet HD209458b p143

A. Vidal-Madjar, A. Lecavelier des Etangs, J.-M. Désert, G. E. Ballester, R. Ferlet, G. Hébrard and M. Mayor

doi:10.1038/nature01448

See also: News and Views by Charbonneau


Observation of two-dimensional discrete solitons in optically induced nonlinear photonic lattices p147

Jason W. Fleischer, Mordechai Segev, Nikolaos K. Efremidis and Demetrios N. Christodoulides

doi:10.1038/nature01452


Self-organization of dissolved organic matter to micelle-like microparticles in river water p150

Martin Kerner, Heinz Hohenberg, Siegmund Ertl, Marcus Reckermann and Alejandro Spitzy

doi:10.1038/nature01469


Core formation in planetesimals triggered by permeable flow p154

Takashi Yoshino, Michael J. Walter and Tomoo Katsura

doi:10.1038/nature01459

See also: News and Views by Minarik


Escalation of a coevolutionary arms race through host rejection of brood parasitic young p157

Naomi E. Langmore, Sarah Hunt and Rebecca M. Kilner

doi:10.1038/nature01460


Growth dynamics underlying petal shape and asymmetry p161

Anne-Gaëlle Rolland-Lagan, J. Andrew Bangham and Enrico Coen

doi:10.1038/nature01443

See also: News and Views by Desplan & Lecuit


Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1 p164

Emmanuel Treiner, Livine Duban, Seiamak Bahram, Mirjana Radosavljevic, Valerie Wanner, Florence Tilloy, Pierre Affaticati, Susan Gilfillan and Olivier Lantz

doi:10.1038/nature01433


Loss of integrin alphavbeta6-mediated TGF-beta activation causes Mmp12-dependent emphysema p169

David G. Morris, Xiaozhu Huang, Naftali Kaminski, Yanli Wang, Steven D. Shapiro, Gregory Dolganov, Adam Glick and Dean Sheppard

doi:10.1038/nature01413

See also: News and Views by Roberts


Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40 p173

Yasuaki Itoh, Yuji Kawamata, Masataka Harada, Makoto Kobayashi, Ryo Fujii, Shoji Fukusumi, Kazuhiro Ogi, Masaki Hosoya, Yasuhiro Tanaka, Hiroshi Uejima, Hideyuki Tanaka, Minoru Maruyama, Rie Satoh, Shoichi Okubo, Hideki Kizawa, Hidetoshi Komatsu, Fumika Matsumura, Yuko Noguchi, Tokuyuki Shinohara, Shuji Hinuma, Yukio Fujisawa and Masahiko Fujino

doi:10.1038/nature01478


Functional and spatial segregation of secretory vesicle pools according to vesicle age p176

Rory R. Duncan, Jennifer Greaves, Ulrich K. Wiegand, Ioulia Matskevich, Georg Bodammer, David K. Apps, Michael J. Shipston and Robert H. Chow

doi:10.1038/nature01389


Functional analysis of an archaebacterial voltage-dependent K+ channel p180

Vanessa Ruta, Youxing Jiang, Alice Lee, Jiayun Chen and Roderick MacKinnon

doi:10.1038/nature01473


Insight into a natural Diels–Alder reaction from the structure of macrophomate synthase p185

Toyoyuki Ose, Kenji Watanabe, Takashi Mie, Mamoru Honma, Hiromi Watanabe, Min Yao, Hideaki Oikawa and Isao Tanaka

doi:10.1038/nature01454


erratum: Attosecond control of electronic processes by intense light fields p189

A. Baltus caronka, Th. Udem, M. Uiberacker, M. Hentschel, E. Goulielmakls, Ch. Gohle, R. Holzwarth, V. S. Yakovlev, A. Scrinzi, T. W. Hänsch and F. Krausz

doi:10.1038/nature01483


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insight

introduction

proteomics p191

Barbara Marte

doi:10.1038/422191a


overview

From genomics to proteomics p193

Mike Tyers and Matthias Mann

doi:10.1038/nature01510


review article

Mass spectrometry-based proteomics p198

Ruedi Aebersold and Matthias Mann

doi:10.1038/nature01511


Protein analysis on a proteomic scale p208

Eric Phizicky, Philippe I. H. Bastiaens, Heng Zhu, Michael Snyder and Stanley Fields

doi:10.1038/nature01512


From words to literature in structural proteomics p216

Andrej Sali, Robert Glaeser, Thomas Earnest and Wolfgang Baumeister

doi:10.1038/nature01513


Disease proteomics p226

Sam Hanash

doi:10.1038/nature01514


Biomedical informatics for proteomics p233

Mark S. Boguski and Martin W. McIntosh

doi:10.1038/nature01515


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Naturejobs

Prospects

Eastern promises p239

Paul Smaglik

doi:10.1038/nj6928-239a


REGIONS

San Diego: California dreaming p240

Paul Smaglik

doi:10.1038/nj6928-240a


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