Table of contents
Volume 415 Number 6868 pp3-244
Naturejobs
ProspectsMoving benchmarks p3
Paul Smaglik
doi:10.1038/nj6868-03a
postdocs
Postdocs & students: Private foundations push for higher postdoc salaries p5
Karen Kreeger
doi:10.1038/nj6868-05a
Opinion
Errors in citation statistics p101
A curious absence from a list of 'hot papers' has led Nature to uncover some inaccuracies in the citation statistics compiled by the ISI. This adds to worries about relying heavily on these figures when rating scientific performance.
doi:10.1038/415101a
Lynch mob turns on lynx researchers p101
Biologists who tried to test the performance of a lab conducting genetic analysis have been unfairly pilloried.
doi:10.1038/415101b
News
Xenotransplant experts express caution over knockout piglets p103
Declan Butler
doi:10.1038/415103a
Clone pioneer calls for health tests p103
David Adam
doi:10.1038/415103b
Argentina's crisis heralds time of torment for scientists p104
Carol Marzuola
doi:10.1038/415104a
Legal move could open door to physics lab p105
Irwin Goodwin
doi:10.1038/415105a
Bushfires leave ecologists hot under the collar p105
Peter Pockley
doi:10.1038/415105b
Whale deaths caused by US Navy's sonar p106
Mark Schrope
doi:10.1038/415106a
NIH faces action over HIV cat study p106
Erika Check
doi:10.1038/415106b
Fur flies over lynx survey's suspect samples p107
Rex Dalton
doi:10.1038/415107a
Charges over computing project may set precedent p107
Erika Check
doi:10.1038/415107b
news feature
Shorter, brighter, better p110
A laser technology with military roots looks set to make a big impact on biology. By creating short pulses of intense radiation, free-electron lasers will advance our understanding of biological molecules. Navroz Patel reports.
Navroz Patel
doi:10.1038/415110a
Betting on tomorrow's chips p112
At the proteomics frontier, dozens of companies are trying to develop the protein equivalent of DNA microarrays. But designing these chips poses much tougher technical challenges, says Alison Abbott.
Alison Abbott
doi:10.1038/415112a
Correspondence
Theoretical models of sheep BSE reveal possibilities p115
But we must remember that these theories are based on speculation, not on fact.
John R. Krebs, Robert M. May and Michael P. H. Stumpf
doi:10.1038/415115a
Dropped genetics paper lacked scientific merit p115
Neil Risch, Alberto Piazza and L. Luca Cavalli-Sforza
doi:10.1038/415115b
Book Reviews
Why natural may not equal healthy p117
Many believe that the natural toxins in their food are safer than synthetic ones.
John Krebs reviews Naturally Dangerous: Surprising Facts about Food, Health, and the Environment by James P. Collman
doi:10.1038/415117a
Life as a freeloader p117
J. C. Koella and C. D. M. Müller-Graf review Les associations du vivant: L'art d'être parasite by Claude Combes
doi:10.1038/415117b
A Universal view p119
John E. Chambers reviews Higher Than Everest: An Adventurer's Guide to the Solar System by Paul Hodge and Solar System Evolution: A New Perspective. 2nd edition by Stuart Ross Taylor
doi:10.1038/415119a
A jaunt through the Solar System p119
doi:10.1038/415119b
Talking techno p120
Geoffrey Nunberg reviews Language and the Internet by David Crystal
doi:10.1038/415120a
Gone — but not forgotten p120
doi:10.1038/415120b
News and Views
Proteomics: Protein complexes take the bait p123
Many cellular functions are carried out by proteins that are bound together in complexes. In two new large-scale studies, labelled proteins are used as 'bait' to capture and identify those complexes.
Anuj Kumar and Michael Snyder
doi:10.1038/415123a
Oceanography: Bubbling under p124
The study of hydrothermal vents is a young and fertile discipline. The latest findings, and the enticing prospects offered by new technology, came in for discussion at two meetings held late last year.
Chris German
doi:10.1038/415124a
Behavioural science: Homo reciprocans p125
Humans are often generous, but cooperation unravels when others take advantage of them. Many people punish such 'free riders', even if they do not benefit personally, and this 'altruistic punishment' sustains cooperation.
Samuel Bowles and Herbert Gintis
doi:10.1038/415125a
100 and 50 years ago p127
doi:10.1038/415127a
Astronomy: X-rays reveal the Galaxy's centre p128
For twenty years astronomers have wondered what is responsible for the X-ray emission from the centre of our Galaxy. New data from the sharpest X-ray eye around — the Chandra observatory — reveal all.
Andreas Eckart
doi:10.1038/415128a
Molecular motors: Stretching the lever-arm theory p129
Motor proteins are essential to life: without them, all cellular transport would grind to a halt. New results on the size of steps taken by one family of motors, the myosins, will fuel the debate about how they move.
Michael A. Geeves
doi:10.1038/415129a
Global change: Getting cool with nitrogen p131
Variations in the marine nitrogen cycle are implicated in driving glacial–interglacial climate change and producing warm spells during glacial periods. But phosphorus may also need to be taken into account.
Allan H. Devol
doi:10.1038/415131a
Daedalus: Hold on to your heat p132
David Jones
doi:10.1038/415132a
Brief Communications
Visual systems: Predator and prey views of spider camouflage p133
Both hunter and hunted fail to notice crab-spiders blending with coloured petals.
Marc Théry and Jérôme Casas
doi:10.1038/415133a
First paragraph | Full Text | PDF (95K) | Supplementary information
Brain evolution (Communication arising): Analysis of mammalian brain architecture p133
Fahad Sultan
doi:10.1038/415133b
First paragraph | Full Text | PDF (95K)
Brain evolution (Communications arising): How did brains evolve? p134
Robert A. Barton
doi:10.1038/415134a
First paragraph | Full Text | PDF (72K)
Brain evolution (Communications arising): How did brains evolve? p135
Samuel S.-H. Wang, Partha P. Mitra and Damon A. Clark
doi:10.1038/415135a
First paragraph | Full Text | PDF (40K)
Articles
Altruistic punishment in humans p137
Ernst Fehr and Simon Gächter
doi:10.1038/415137a
Abstract | Full Text | PDF (97K)
See also: News and Views by Bowles & Gintis
Functional organization of the yeast proteome by systematic analysis of protein complexes p141
Anne-Claude Gavin, Markus Bösche, Roland Krause, Paola Grandi, Martina Marzioch, Andreas Bauer, Jörg Schultz, Jens M. Rick, Anne-Marie Michon, Cristina-Maria Cruciat, Marita Remor, Christian Höfert, Malgorzata Schelder, Miro Brajenovic, Heinz Ruffner, Alejandro Merino, Karin Klein, Manuela Hudak, David Dickson, Tatjana Rudi, Volker Gnau, Angela Bauch, Sonja Bastuck, Bettina Huhse, Christina Leutwein, Marie-Anne Heurtier, Richard R. Copley, Angela Edelmann, Erich Querfurth, Vladimir Rybin, Gerard Drewes, Manfred Raida, Tewis Bouwmeester, Peer Bork, Bertrand Seraphin, Bernhard Kuster, Gitte Neubauer and Giulio Superti-Furga
doi:10.1038/415141a
Abstract | Full Text | PDF (428K) | Supplementary information
See also: News and Views by Kumar & Snyder
Letters to Nature
A faint discrete source origin for the highly ionized iron emission from the Galactic Centre region p148
Q. D. Wang, E. V. Gotthelf and C. C. Lang
doi:10.1038/415148a
First paragraph | Full Text | PDF (260K)
See also: News and Views by Eckart
Transition-metal-based magnetic refrigerants for room-temperature applications p150
O. Tegus, E. Brück, K. H. J. Buschow and F. R. de Boer
doi:10.1038/415150a
First paragraph | Full Text | PDF (148K)
Remote electronic control of DNA hybridization through inductive coupling to an attached metal nanocrystal antenna p152
Kimberly Hamad-Schifferli, John J. Schwartz, Aaron T. Santos, Shuguang Zhang and Joseph M. Jacobson
doi:10.1038/415152a
First paragraph | Full Text | PDF (211K) | Supplementary information
Reduced nitrogen fixation in the glacial ocean inferred from changes in marine nitrogen and phosphorus inventories p156
Raja S. Ganeshram, Thomas F. Pedersen, Stephen Calvert and Roger François
doi:10.1038/415156a
First paragraph | Full Text | PDF (182K)
See also: News and Views by Devol
The effect of millennial-scale changes in Arabian Sea denitrification on atmospheric CO2 p159
Mark A. Altabet, Matthew J. Higginson and David W. Murray
doi:10.1038/415159a
First paragraph | Full Text | PDF (474K) | Supplementary information
See also: News and Views by Devol
Parasitic Cape honeybee workers, Apis mellifera capensis, evade policing p163
Stephen J. Martin, Madeleine Beekman, Theresa C. Wossler and Francis L. W. Ratnieks
doi:10.1038/415163a
First paragraph | Full Text | PDF (160K)
Dynamic coding of behaviourally relevant stimuli in parietal cortex p165
Louis J. Toth and John A. Assad
doi:10.1038/415165a
First paragraph | Full Text | PDF (260K)
Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo p168
Hiromi Yanagisawa, Elaine C. Davis, Barry C. Starcher, Takashi Ouchi, Masashi Yanagisawa, James A. Richardson and Eric N. Olson
doi:10.1038/415168a
First paragraph | Full Text | PDF (394K) | Supplementary information
Fibulin-5/DANCE is essential for elastogenesis in vivo p171
Tomoyuki Nakamura, Pilar Ruiz Lozano, Yasuhiro Ikeda, Yoshitaka Iwanaga, Aleksander Hinek, Susumu Minamisawa, Ching-Feng Cheng, Kazuhiro Kobuke, Nancy Dalton, Yoshikazu Takada, Kei Tashiro, John Ross Jr, Tasuku Honjo and Kenneth R. Chien
doi:10.1038/415171a
First paragraph | Full Text | PDF (464K) | Supplementary information
Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface p175
George L. Dale, Paul Friese, Peter Batar, Stephen F. Hamilton, Guy L. Reed, Kenneth W. Jackson, Kenneth J. Clemetson and Lorenzo Alberio
doi:10.1038/415175a
First paragraph | Full Text | PDF (249K) | Supplementary information
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry p180
Yuen Ho, Albrecht Gruhler, Adrian Heilbut, Gary D. Bader, Lynda Moore, Sally-Lin Adams, Anna Millar, Paul Taylor, Keiryn Bennett, Kelly Boutilier, Lingyun Yang, Cheryl Wolting, Ian Donaldson, Søren Schandorff, Juanita Shewnarane, Mai Vo, Joanne Taggart, Marilyn Goudreault, Brenda Muskat, Cris Alfarano, Danielle Dewar, Zhen Lin, Katerina Michalickova, Andrew R. Willems, Holly Sassi, Peter A. Nielsen, Karina J. Rasmussen, Jens R. Andersen, Lene E. Johansen, Lykke H. Hansen, Hans Jespersen, Alexandre Podtelejnikov, Eva Nielsen, Janne Crawford, Vibeke Poulsen, Birgitte D. Sørensen, Jesper Matthiesen, Ronald C. Hendrickson, Frank Gleeson, Tony Pawson, Michael F. Moran, Daniel Durocher, Matthias Mann, Christopher W. V. Hogue, Daniel Figeys and Mike Tyers
doi:10.1038/415180a
First paragraph | Full Text | PDF (217K) | Supplementary information
See also: News and Views by Kumar & Snyder
Alternative nucleotide incision repair pathway for oxidative DNA damage p183
Alexander A. Ischenko and Murat K. Saparbaev
doi:10.1038/415183a
First paragraph | Full Text | PDF (191K) | Supplementary information
Co-regulator recruitment and the mechanism of retinoic acid receptor synergy p187
Pierre Germain, Jaya Iyer, Christina Zechel and Hinrich Gronemeyer
doi:10.1038/415187a
First paragraph | Full Text | PDF (247K)
The motor domain determines the large step of myosin-V p192
Hiroto Tanaka, Kazuaki Homma, Atsuko Hikikoshi Iwane, Eisaku Katayama, Reiko Ikebe, Junya Saito, Toshio Yanagida and Mitsuo Ikebe
doi:10.1038/415192a
First paragraph | Full Text | PDF (249K)
See also: News and Views by Geeves
New on the Market
January sales p196
A miscellany from recent product launches.
doi:10.1038/415196a
insight
forewordthe heart p197
Karen Birmingham
doi:10.1038/415197a
review article
Cardiac excitation–contraction coupling p198
Donald M. Bers
doi:10.1038/415198a
Abstract | Full Text | PDF (566K)
Seven-transmembrane-spanning receptors and heart function p206
Howard A. Rockman, Walter J. Koch and Robert J. Lefkowitz
doi:10.1038/415206a
Abstract | Full Text | PDF (450K)
Cardiac channelopathies p213
Eduardo Marbán
doi:10.1038/415213a
Abstract | Full Text | PDF (408K)
New ideas about atrial fibrillation 50 years on p219
Stanley Nattel
doi:10.1038/415219a
Abstract | Full Text | PDF (219K)
The failing heart p227
J. A. Towbin and N. E. Bowles
doi:10.1038/415227a
Abstract | Full Text | PDF (575K)
Myocardial gene therapy p234
Jeffrey M. Isner
doi:10.1038/415234a
Abstract | Full Text | PDF (316K)
progress
Myocyte renewal and ventricular remodelling p240
Piero Anversa and Bernardo Nadal-Ginard
doi:10.1038/415240a
Abstract | Full Text | PDF (570K)
corporate support
The Heart and Drug Therapy p244
Peter Thoren, Ingemar Jacobson, Håkan Wennbo and Mikael Dohlsten
doi:10.1038/415244a


