Table of contents
Volume 414 Number 6860 pp3-234
Naturejobs
ProspectsBig or small neuroscience? p3
Paul Smaglik
doi:10.1038/35102741
Careers and Recruitment
All systems go for neuroscience p4
Multidisciplinary approaches pave the way towards new frontiers in understanding complex human behaviour and intractable diseases. Diane Gershon assesses the US field.
Diane Gershon
doi:10.1038/35102743
A grassroots revolution p6
America may be thinking big, but in Europe the rise of neuroscience is finding favour in a more localized manner. Helen Gavaghan taps into the continental flavour of European interdisciplinary research.
Helen Gavaghan
doi:10.1038/35102748
Limited opportunity p8
Japan's Brain Science Institute offers young neuroscientists jobs — but doesn't guarantee them long-term employment, says Robert Triendl.
Robert Triendl
doi:10.1038/35102753
Opinion
A stain on Italian reforms p133
Italy's principal funding agency has missed an opportunity to enhance the prestige of its institutes. In appointing its first crop of new directors, it has conspicuously avoided some candidates of the highest calibre.
doi:10.1038/35102688
Visionary experimental designs p133
A collaboration marrying epidemiology and genomics should provide a much-needed boost to analytical rigour.
doi:10.1038/35102690
News
Geneticists' work in disarray as DNA-chip producer pulls the plug p135
Jonathan Knight
doi:10.1038/35102692
New Zealand says yes to GM trials p135
Peter Pockley
doi:10.1038/35102695
Critical report leaves NASA's station strategy up in the air p136
William Triplett
doi:10.1038/35102697
Universities address mail security as anthrax fears rise p136
Jonathan Knight
doi:10.1038/35102700
Bush adviser vows to find science its voice p137
Matthew Davis
doi:10.1038/35102702
Knowledge at stake in Australian poll p137
Peter Pockley
doi:10.1038/35102705
Drug price deal spells windfall for researchers p138
Xavier Bosch
doi:10.1038/35102709
Disputed diagnoses hamper claims of mercury poisoning p138
David Cyranoski
doi:10.1038/35102711
Epidemiology set to get fast-track treatment p139
Declan Butler
doi:10.1038/35102713
Museums choked by bone law p139
Rex Dalton
doi:10.1038/35102716
news feature
Roll up for the revolution p142
In the early 1990s, a chance finding in a Japanese laboratory introduced the world to carbon nanotubes. Today, interest in the tubes is still growing. Philip Ball reports on a decade of discovery.
Philip Ball
doi:10.1038/35102721
Young, gifted...and spurned p145
While their contemporaries in other countries zip from postdoc to postdoc, young French scientists struggle to find work. Sally Goodman reports.
Sally Goodman
doi:10.1038/35102625
Correspondence
BSE fostered by cosinesss and lack of independent advice p147
Japan needs experienced scientists in positions of power to make reliable assessments of government advice
Mitsuo Tagaya
doi:10.1038/35102727
Meat and bone meal still used in animal feed p147
Stephen Rossides
doi:10.1038/35102729
Tantalizing glimpse of a vanishing dinosaur p147
Eric Buffetaut
doi:10.1038/35102731
Once again, insects worked it out first p147
M. Inbar and J. C. Schultz
doi:10.1038/35102733
Disclosure of interests: there's a long way to go p148
Tamsen Valoir
doi:10.1038/35102735
Sequenced strains must be saved from extinction p148
Naomi Ward, Jonathan Eisen, Claire Fraser and Erko Stackebrandt
doi:10.1038/35102737
Taxonomists make a name for themselves p148
Gerard van der Velde
doi:10.1038/35102739
Book Reviews
No need to worry about the future p149
Environmentally, we are told, 'things are getting better'.
Stuart Pimm and Jeff Harvey review The Skeptical Environmentalist: Measuring the Real State of the World by Bjørn Lomborg
doi:10.1038/35102629
Those with no future p149
doi:10.1038/35102631
Tragic outcome of extreme conditions p150
Cornelia Lüdecke reviews The Coldest March: Scott's Fatal Antarctic Expedition By Susan Solomon
doi:10.1038/35102634
Medical masterpieces p151
doi:10.1038/35102637
Bumps on the brain p151
John C. Marshall reviews The New Phrenology: The Limits of Localizing Cognitive Processes in the Brain by William R. Uttal
doi:10.1038/35102640
Science in culture p152
Heike Langenberg reviews
doi:10.1038/35102642
words
The tracks of thought p153
In both science and technology, metaphors direct the way we think, reason and hypothesize.
Douwe Draaisma
doi:10.1038/35102645
News and Views
Looking down is looking up p155
How do we perceive distance using only one eye? A neat variation on existing methods of measuring visually perceived distance highlights the importance of 'angular declination', a cue long thought to be involved.
Jack M. Loomis
doi:10.1038/35102648
Biophysics: Water at the nanoscale p156
You would not expect water to enter a hydrophobic carbon nanotube. But computer simulations show that it can, and studying the process should provide clues about the behaviour of biological pores.
Mark S. P. Sansom and Philip C. Biggin
doi:10.1038/35102651
100 and 50 years ago p157
doi:10.1038/35102654
Alzheimer's disease: An inflammatory drug prospect p159
There is no known cure for Alzheimer's disease. But new hope (for mice at least) comes from an in-depth investigation of a class of drugs used to treat inflammatory diseases.
Bart De Strooper and Gerhard König
doi:10.1038/35102656
Microbiology: Tackling anthrax p160
Antibiotic development is the first priority in responding to terrorist use of anthrax. But structural studies offer new leads in the hunt for more effective anti-toxin treatments.
Arthur M. Friedlander
doi:10.1038/35102660
Papermaking: Green chemistry through the mill p161
Turning wood into paper uses lots of chemicals, whose waste products are a serious environmental concern. A new approach to the problem conjures up some clever chemistry but shows that there are no quick fixes.
Terry Collins
doi:10.1038/35102662
Developmental biology: Gridlock in the blood p163
All blood vessels originate from the same precursor cells in early embryos. So how do those precursors decide whether to contribute to arteries or veins? Studies of zebrafish bring us closer to the answer.
Gavin Thurston and George D. Yancopoulos
doi:10.1038/35102664
Daedalus: Vacuum in miniature p164
David Jones
doi:10.1038/35102667
Brief Communications
Sheep don't forget a face p165
The discovery of a remarkable memory shows that sheep are not so stupid after all.
Keith M. Kendrick, Ana P. da Costa, Andrea E. Leigh, Michael R. Hinton and Jon W. Peirce
doi:10.1038/35102669
First paragraph | Full Text | PDF (132K)
Eutrophication: Nitrate flux in the Mississippi River p166
Gregory F. McIsaac, Mark B. David, George Z. Gertner and Donald A. Goolsby
doi:10.1038/35102672
First paragraph | Full Text | PDF (71K) | Supplementary information
Neural-network models: Predicting spontaneous recovery of memory p167
James V. Stone, Nicola M. Hunkin and Angela Hornby
doi:10.1038/35102676
First paragraph | Full Text | PDF (130K)
Parasitic infection: Hunger tolerance and Leishmania in sandflies p168
Yosef Schlein and Raymond L. Jacobson
doi:10.1038/35102679
First paragraph | Full Text | PDF (103K)
correction p168
doi:10.1038/35102682
Progress
Recent patterns and mechanisms of carbon exchange by terrestrial ecosystems p169
D. S. Schimel, J. I. House, K. A. Hibbard, P. Bousquet, P. Ciais, P. Peylin, B. H. Braswell, M. J. Apps, D. Baker, A. Bondeau, J. Canadell, G. Churkina, W. Cramer, A. S. Denning, C. B. Field, P. Friedlingstein, C. Goodale, M. Heimann, R. A. Houghton, J. M. Melillo, B. Moore, III, D. Murdiyarso, I. Noble, S. W. Pacala, I. C. Prentice, M. R. Raupach, P. J. Rayner, R. J. Scholes, W. L. Steffen and C. Wirth
doi:10.1038/35102500
Abstract | Full Text | PDF (149K)
Article
Genetic tracing reveals a stereotyped sensory map in the olfactory cortex p173
Zhihua Zou, Lisa F. Horowitz, Jean-Pierre Montmayeur, Scott Snapper and Linda B. Buck
doi:10.1038/35102506
Abstract | Full Text | PDF (506K)
Letters to Nature
Correlated fast X-ray and optical variability in the black-hole candidate XTE J1118+480 p180
G. Kanbach, C. Straubmeier, H. C. Spruit and T. Belloni
doi:10.1038/35102515
First paragraph | Full Text | PDF (161K)
Absolute-phase phenomena in photoionization with few-cycle laser pulses p182
G. G. Paulus, F. Grasbon, H. Walther, P. Villoresi, M. Nisoli, S. Stagira, E. Priori and S. De Silvestri
doi:10.1038/35102520
First paragraph | Full Text | PDF (159K)
Sharper images by focusing soft X-rays with photon sieves p184
L. Kipp, M. Skibowski, R. L. Johnson, R. Berndt, R. Adelung, S. Harm and R. Seemann
doi:10.1038/35102526
First paragraph | Full Text | PDF (401K)
Water conduction through the hydrophobic channel of a carbon nanotube p188
G. Hummer, J. C. Rasaiah and J. P. Noworyta
doi:10.1038/35102535
First paragraph | Full Text | PDF (223K)
See also: News and Views by Sansom & Biggin
Equilibrating metal-oxide cluster ensembles for oxidation reactions using oxygen in water p191
Ira A. Weinstock, Elena M.G. Barbuzzi, Michael W. Wemple, Jennifer J. Cowan, Richard S. Reiner, Dan M. Sonnen, Robert A. Heintz, James S. Bond and Craig L. Hill
doi:10.1038/35102545
First paragraph | Full Text | PDF (319K) | Supplementary information
See also: News and Views by Collins
Determinants of establishment success in introduced birds p195
Tim M. Blackburn and Richard P. Duncan
doi:10.1038/35102557
First paragraph | Full Text | PDF (139K) | Supplementary information
Distance determined by the angular declination below the horizon p197
Teng Leng Ooi, Bing Wu and Zijiang J. He
doi:10.1038/35102562
First paragraph | Full Text | PDF (151K)
Linear processing of spatial cues in primary auditory cortex p200
Jan W. H. Schnupp, Thomas D. Mrsic-Flogel and Andrew J. King
doi:10.1038/35102568
First paragraph | Full Text | PDF (612K)
Target neuron prespecification in the olfactory map of Drosophila p204
Gregory S. X. E. Jefferis, Elizabeth C. Marin, Reinhard F. Stocker and Liqun Luo
doi:10.1038/35102574
First paragraph | Full Text | PDF (517K) | Supplementary information
An anorexic lipid mediator regulated by feeding p209
F. Rodríguez de Fonseca, M. Navarro, R. Gómez, L. Escuredo, F. Nava, J. Fu, E. Murillo-Rodríguez, A. Giuffrida, J. LoVerme, S. Gaetani, S. Kathuria, C. Gall and D. Piomelli
doi:10.1038/35102582
First paragraph | Full Text | PDF (204K) | Supplementary information
A subset of NSAIDs lower amyloidogenic A
42 independently of cyclooxygenase activity p212
Sascha Weggen, Jason L. Eriksen, Pritam Das, Sarah A. Sagi, Rong Wang, Claus U. Pietrzik, Kirk A. Findlay, Tawnya E. Smith, Michael P. Murphy, Thomas Bulter, David E. Kang, Numa Marquez-Sterling, Todd E. Golde and Edward H. Koo
doi:10.1038/35102591
First paragraph | Full Text | PDF (196K) | Supplementary information
See also: News and Views by De Strooper & König
Gridlock signalling pathway fashions the first embryonic artery p216
Tao P. Zhong, Sarah Childs, James P. Leu and Mark C. Fishman
doi:10.1038/35102599
First paragraph | Full Text | PDF (578K)
See also: News and Views by Thurston & Yancopoulos
Asynchronous replication and allelic exclusion in the immune system p221
Raul Mostoslavsky, Nandita Singh, Toyoaki Tenzen, Maya Goldmit, Chana Gabay, Sharon Elizur, Peimin Qi, Benjamin E. Reubinoff, Andrew Chess, Howard Cedar and Yehudit Bergman
doi:10.1038/35102606
First paragraph | Full Text | PDF (221K)
Identification of the cellular receptor for anthrax toxin p225
Kenneth A. Bradley, Jeremy Mogridge, Michael Mourez, R. John Collier and John A. T. Young
doi:10.1038/n35101999
First paragraph | Full Text | PDF (333K)
See also: News and Views by Friedlander
Crystal structure of the anthrax lethal factor p229
Andrew D. Pannifer, Thiang Yian Wong, Robert Schwarzenbacher, Martin Renatus, Carlo Petosa, Jadwiga Bienkowska, D. Borden Lacy, R. John Collier, Sukjoon Park, Stephen H. Leppla, Philip Hanna and Robert C. Liddington
doi:10.1038/n35101998
First paragraph | Full Text | PDF (315K) | Supplementary information
See also: News and Views by Friedlander
New on the Market
Neuroscience on the brain p234
Antibodies, reagents and equipment for neuroscience research.
doi:10.1038/35102684
