Table of contents


Top

Opinion

For the want of a test. . . p649

As Europe wrestles with its BSE crisis, the top priority is to develop a diagnostic test that can reliably identify animals incubating the disease and people incubating its human form.

doi:10.1038/35055664


Handling (mis?)appropriated data p649

Introducing a policy to ensure due credit for unpublished data.

doi:10.1038/35055666


Top

News

Japan's ape sequencing effort set to unravel the brain's secrets p651

David Cyranoski

doi:10.1038/35055668


Science 'in crisis' says commission p651

Irwin Goodwin

doi:10.1038/35055671


Japanese premier underlines opposition to human cloning p652

David Cyranoski

doi:10.1038/35055673


Italian biologists left out in the cold p652

Alison Abbott

doi:10.1038/35055676


Germany targets international talent p652

Quirin Schiermeier

doi:10.1038/35055679


Greek plutonium haul raises smuggling fears p653

Quirin Schiermeier

doi:10.1038/35055681


Top research universities face up to gender bias p653

Steve Nadis

doi:10.1038/35055684


India struggles to cope with IT brain drain p654

K. S. Jayaraman

doi:10.1038/35055687


NASA celebrates as spacecraft homes in on asteroid p654

William Triplett

doi:10.1038/35055690


Australian leader pledges research boost before election p655

Peter Pockley

doi:10.1038/35055693


Tissue donations slump after revelations about misuse p655

David Adam

doi:10.1038/35055696


news in brief p656

doi:10.1038/35055699


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news feature

Testing times for BSE p658

No one knows whether the diagnostic tests being used to search for BSE infection in Europe's cattle can reliably detect animals incubating the disease. Given this limitation, asks Quirin Schiermeier, what is the testing programme likely to achieve?

Quirin Schiermeier

doi:10.1038/35055703


In search of a cure for CJD p660

Many thousands of people may be incubating the human form of BSE. Could drugs or other therapeutic agents prevent them from succumbing? Clare Thompson reports on the race against time to find a treatment.

Clare Thompson

doi:10.1038/35055708


Top

Correspondence

Leaders need to realize that science can offer a route out of poverty p662

Germán Poveda

doi:10.1038/35055714


Secret behind Hungary's stellar intellects p662

Leon Eisenberg

doi:10.1038/35055716


Why didn't flood of print launch science in China? p662

P. -L. Chau

doi:10.1038/35055718


Top

Book Reviews

Fit for the seven-league boots p663

The story of a man who sought to harness nature for the American good.

Richard White reviews A River Running West: The Life of John Wesley Powell by Donald Worster

doi:10.1038/35055602


Taxonomy and the blues p664

James Mallet reviews Nabokov's Blues: The Scientific Odyssey of a Literary Genius by Kurt Johnson and Steve Coates

doi:10.1038/35055606


Wings and other things p664

doi:10.1038/35055608


Crash, bang, wallop p665

Bernard Richardson reviews Science of Percussion Instruments by Thomas D. Rossing

doi:10.1038/35055611


Science in culture p666

Martin Kemp reviews

doi:10.1038/35055614


Top

words

Gained in the translation p667

Scientific knowledge is enriched as it moves between languages.

Scott L. Montgomery

doi:10.1038/35055634


Top

concepts

The big picture p669

Sean B. Carroll

doi:10.1038/35055637


Top

News and Views

The dark side of aerosols p671

According to new modelling calculations, black carbon in the atmosphere exerts a large warming influence on global climate. Curbing emissions of this pollutant may be advisable both on climate and on human health grounds.

Meinrat O. Andreae

doi:10.1038/35055640


Diabetes: Dialogue between muscle and fat p672

Knocking out a glucose transporter in fat cells also affects the uptake of glucose into muscle cells, which may prompt a rethink of the transporter's role in diabetes.

Morris J. Birnbaum

doi:10.1038/35055643


Astronomy: The age of the Universe p673

Dating the Universe has always been a tricky business with unsatisfying answers. Astronomers now have a better clock, based on radioactive uranium, that puts the age at around 12.5 billion years.

Christopher Sneden

doi:10.1038/35055646


Evolution: Infectious speciation p675

The bacterium Wolbachia has strange and wonderful effects on reproduction in its many invertebrate host species. In effect, the creation of new species can now be added to the list.

Michael J. Wade

doi:10.1038/35055648


100 and 50 Years ago p675

doi:10.1038/35055652


Astronomy: The day the solar wind nearly died p677

On 11 May 1999, the density of the solar wind dropped almost to zero. Space scientists are now giving their first reports of this rare opportunity to study the complex relationship between the Sun and Earth.

Mike Lockwood

doi:10.1038/35055654


Developmental biology: A macho way to make muscles p679

The 'mosaic' theory of development applies, to different degrees, to most animals. It owes its existence in part to a group of obscure marine invertebrates, which now take centre stage in the molecular age.

Olivier Pourquié

doi:10.1038/35055657


Top

Brief Communications

Dominant rams lose out by sperm depletion p681

A waning success in siring counters a ram's high score in competition for ewes.

Brian T. Preston, Ian R. Stevenson, Josephine M. Pemberton and Kenneth Wilson

doi:10.1038/35055617


Biotechnology: Transgenic crops in natural habitats p682

M. J. Crawley, S. L. Brown, R. S. Hails, D. D. Kohn and M. Rees

doi:10.1038/35055621


Materials science: Nanoscale control of chain polymerization p683

Yuji Okawa and Masakazu Aono

doi:10.1038/35055625


Gene expression: View of a mouse clock gene ticking p684

Shun Yamaguchi, Masaki Kobayashi, Shigeru Mitsui, Yoshiki Ishida, Gijsbertus T. J. van der Horst, Misao Suzuki, Shigenobu Shibata and Hitoshi Okamura

doi:10.1038/35055628


Top

Article

Functional annotation of a full-length mouse cDNA collection p685

J. Kawai, A. Shinagawa, K. Shibata, M. Yoshino, M. Itoh, Y. Ishii, T. Arakawa, A. Hara, Y. Fukunishi, H. Konno, J. Adachi, S. Fukuda, K. Aizawa, M. Izawa, K. Nishi, H. Kiyosawa, S. Kondo, I. Yamanaka and T. Saito


Top

Letters to Nature

Measurement of stellar age from uranium decay p691

R. Cayrel, V. Hill, T. C. Beers, B. Barbuy, M. Spite, F. Spite, B. Plez, J. Andersen, P. Bonifacio, P. François, P. Molaro, B. Nordström and F. Primas

doi:10.1038/35055507

See also: News and Views by Sneden


Generic mechanism for generating a liquid–liquid phase transition p692

Giancarlo Franzese, Gianpietro Malescio, Anna Skibinsky, Sergey V. Buldyrev and H. Eugene Stanley

doi:10.1038/35055514


Strong radiative heating due to the mixing state of black carbon in atmospheric aerosols p695

Mark Z. Jacobson

doi:10.1038/35055518

See also: News and Views by Andreae


Tropical climate changes at millennial and orbital timescales on the Bolivian Altiplano p698

Paul A. Baker, Catherine A. Rigsby, Geoffrey O. Seltzer, Sherilyn C. Fritz, Tim K. Lowenstein, Niklas P. Bacher and Carlos Veliz

doi:10.1038/35055524


Upper-mantle dynamics revealed by helium isotope variations along the southeast Indian ridge p701

D. W. Graham, J. E. Lupton, F. J. Spera and D. M. Christie

doi:10.1038/35055529


Complete mitochondrial genome sequences of two extinct moas clarify ratite evolution p704

Alan Cooper, Carles Lalueza-Fox, Simon Anderson, Andrew Rambaut, Jeremy Austin and Ryk Ward

doi:10.1038/35055536


Wolbachia-induced incompatibility precedes other hybrid incompatibilities in Nasonia p707

Seth R. Bordenstein, F. Patrick O'Hara and John H. Werren

doi:10.1038/35055543

See also: News and Views by Wade


Evolutionary radiations and convergences in the structural organization of mammalian brains p710

Willem de Winter and Charles E. Oxnard

doi:10.1038/35055547


Neurons derived from radial glial cells establish radial units in neocortex p714

Stephen C. Noctor, Alexander C. Flint, Tamily A. Weissman, Ryan S. Dammerman and Arnold R. Kriegstein

doi:10.1038/35055553


The gating mechanism of the large mechanosensitive channel MscL p720

Sergei Sukharev, Monica Betanzos, Chien-Sung Chiang and H. Robert Guy

doi:10.1038/35055559


macho-1 encodes a localized mRNA in ascidian eggs that specifies muscle fate during embryogenesis p724

Hiroki Nishida and Kaichiro Sawada

doi:10.1038/35055568

See also: News and Views by Pourquié


Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver p729

E. Dale Abel, Odile Peroni, Jason K. Kim, Young-Bum Kim, Olivier Boss, Ed Hadro, Timo Minnemann, Gerald I. Shulman and Barbara B. Kahn

doi:10.1038/35055575

See also: News and Views by Birnbaum


Negative regulation of T-cell activation and autoimmunity by Mgat5N-glycosylation p733

Michael Demetriou, Maria Granovsky, Sue Quaggin and James W. Dennis

doi:10.1038/35055582


Crystal structure of photosystem II from Synechococcus elongatus at 3.8 Å resolution p739

Athina Zouni, Horst-Tobias Witt, Jan Kern, Petra Fromme, Norbert Krauss, Wolfram Saenger and Peter Orth

doi:10.1038/35055589


Top

Articles

correction: Language trees support the express-train sequence of Austronesian expansion p743

Russell D. Gray and Fiona M. Jordan

doi:10.1038/35055596


correction: Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 p743

Veronika Souslova, Paolo Cesare, Yanning Ding, Armen N. Akoplan, Louise Stanfa, Rie Suzuki, Katherine Carpenter, Daniela Nebenius-Oosthuizen, Andrew J. H. Smith, Emma J. Kidd and John N. Wood

doi:10.1038/35055598


erratum: The protein–protein interaction map of Helicobacter pylori p743

Jean-Christophe Rain, Luc Selig, Hilde De Reuse, Véronique Battaglia, Céline Reverdy, Stéphane Simon, Gerlinde Lenzen, Fabien Petel, Jérôme Wojcik, Vincent Schächter, Y. Chemama, Agnès Labigne and Pierre Legrain

doi:10.1038/35055600


Top

New on the Market

Image conscious p744

The main theme this week is image acquisition and handling.

doi:10.1038/35055631


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