Opinion

Grounds for hope on AIDS in Africa p219

Despite the pervasive tension between AIDS researchers and the South African government, last week's international AIDS conference in Durban was successful on several fronts.

doi:10.1038/35018685

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SOS (again) at the Department of Energy p219

Congress should provide adequate support for facilities operated on behalf of all US scientists.

doi:10.1038/35018687

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News

Large research facilities to lose out in science spending spree? p221

Colin Macilwain

doi:10.1038/35018689

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Jordan chosen to open SESAME p221

Heather McCabe

doi:10.1038/35018693

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UK space strategy slammed as lacking funds and vision p222

Natasha Loder

doi:10.1038/35018695

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Cluster leaves the ground — at last p222

Natasha Loder

doi:10.1038/35018698

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Diplomatic Mandela calls for action on HIV... p223

Michael Cherry

doi:10.1038/35018701

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...as South Africa considers its options after free drugs offer p223

Michael Cherry

doi:10.1038/35018704

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Diabetes therapy boosts stem-cell campaign p224

Paul Smaglik

doi:10.1038/35018706

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Industry considers carbon catching p224

Steve Nadis

doi:10.1038/35018709

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Enhanced advisory role urged for former EU nuclear labs p225

Quirin Schiermeier

doi:10.1038/35018711

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Brown boosts British science base p225

Natasha Loder

doi:10.1038/35018714

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Recriminations and confusion over 'fake' coelacanth photo p225

Heather McCabe

doi:10.1038/35018716

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Anti-smoking critic wins campaigning right p226

Rex Dalton

doi:10.1038/35018718

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German librarians cautious of brave new digital world p227

Quirin Schiermeier

doi:10.1038/35018721

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News in brief p229

doi:10.1038/35018724

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News Feature

Bones, molecules...or both? p230

Evolutionary trees constructed by studying biological molecules often don't resemble those drawn up from morphology. Can the two ever be reconciled, asks Trisha Gura

Trisha Gura

doi:10.1038/35018729

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Correspondence

Caution is sensible, but give biotech a chance to show the good it can do p234

Enrico Porceddu

doi:10.1038/35018738

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A fault in the 'weak San Andreas' theory p234

C. H. Scholz

doi:10.1038/35018740

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That famous double helix takes a sinister turn p234

Colin Porter

doi:10.1038/35018742

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Book Reviews

The biotechnologist's jungle book p235

Walter Gratzer reviews Medicine Quest: In Search of Nature's Healing Secrets by Mark J. Plotkin

doi:10.1038/35018619

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Healing hues p235

doi:10.1038/35018621

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A function for dysfunction p236

Thomas J. Jentsch reviews Ion Channels and Disease by Frances M. Ashcroft

doi:10.1038/35018624

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Channelling other energies p236

doi:10.1038/35018626

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Conservation gets heavy p237

Rory Howlett reviews Hotspots: Earth's Biologically Richest and Most Endangered Terrestrial Ecoregions by Russell A. Mittermeier, Norman Myers and Cristina Goettsch Mittermeier

doi:10.1038/35018629

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Chemistry's Canterbury Tales p238

John Emsley reviews A Chemical History Tour: Picturing Chemistry from Alchemy to Modern Molecular Science by Arthur Greenberg

doi:10.1038/35018632

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New in paperback p238

doi:10.1038/35018634

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Millennium Essay

Jumbo p239

The revolutionary machine that shrank the world.

Vaclav Smil

doi:10.1038/35018651

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Futures

All is not lost p241

By resurrecting extinct infodiversity, we may save our own culture.

Scott Westerfeld

doi:10.1038/35018654

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News and Views

Faster than a speeding photon p243

The textbooks say nothing can travel faster than light, not even light itself. New experiments show that this is no longer true, raising questions about the maximum speed at which we can send information.

Jon Marangos

doi:10.1038/35018657

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Biophysics: Science in motion p244

Philip Ball

doi:10.1038/35018660

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Neurobiology: Parallel sensing p245

Mathew E. Diamond

doi:10.1038/35018663

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Atmospheric physics: Enlightening water vapour p247

Brian J. Soden

doi:10.1038/35018666

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Human behaviour: Fair game p248

Ruth Mace

doi:10.1038/35018669

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Structural biology: Adding to the antifreeze agenda p249

Charles A. Knight

doi:10.1038/35018671

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Mathematics: Best packing in proteins and DNA p251

Andrzej Stasiak and John H. Maddocks

doi:10.1038/35018674

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100 and 50 years ago p252

doi:10.1038/35018677

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Cell biology: A protein accumulator p253

Jennifer C. Pinder and Anthony J. Baines

doi:10.1038/35018679

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Daedalus: Pulses of the mind p254

David Jones

doi:10.1038/35018683

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Brief Communications

Spider manipulation by a wasp larva p255

A parasitic wasp forces its host to weave a special web for its own ends.

William G. Eberhard

doi:10.1038/35018636

First paragraph | Full Text | PDF (215K)

Phytochemistry: Heat-stable antifreeze protein from grass p256

Chris Sidebottom, Sarah Buckley, Paul Pudney, Sarah Twigg, Carl Jarman, Chris Holt, Julia Telford, Andrew McArthur, Dawn Worrall, Rod Hubbard and Peter Lillford

doi:10.1038/35018639

First paragraph | Full Text | PDF (98K)

See also: News and Views by Knight

Cell differentiation: Hepatocytes from non-hepatic adult stem cells p257

Malcolm R. Alison, Richard Poulsom, Rosemary Jeffery, Amar P. Dhillon, Alberto Quaglia, Joe Jacob, Marco Novelli, Grant Prentice, Jill Williamson and Nicholas A. Wright

doi:10.1038/35018642

First paragraph | Full Text | PDF (145K)

Articles

Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcRI p259

Scott C. Garman, Beth A. Wurzburg, Svetlana S. Tarchevskaya, Jean-Pierre Kinet and Theodore S. Jardetzky

doi:10.1038/35018500

Abstract | Full Text | PDF (431K)

The 3.2-Å crystal structure of the human IgG1 Fc fragment–FcRIII complex p267

Peter Sondermann, Robert Huber, Vaughan Oosthuizen and Uwe Jacob

doi:10.1038/35018508

Abstract | Full Text | PDF (662K)

Letters to Nature

Determining the ages of comets from the fraction of crystalline dust p275

Joseph A. Nuth, III, Hugh G. M. Hill and Gunther Kletetschka

doi:10.1038/35018516

First paragraph | Full Text | PDF (211K)

Gain-assisted superluminal light propagation p277

L. J. Wang, A. Kuzmich and A. Dogariu

doi:10.1038/35018520

First paragraph | Full Text | PDF (301K)

See also: News and Views by Marangos

Non-collinear states in magnetic sensors p280

Adrian Taga, Lars Nordström, Peter James, Börje Johansson and Olle Eriksson

doi:10.1038/35018528

First paragraph | Full Text | PDF (344K)

Imaging the vortex-lattice melting process in the presence of disorder p282

Alex Soibel, Eli Zeldov, Michael Rappaport, Yuri Myasoedov, Tsuyoshi Tamegai, Shuuichi Ooi, Marcin Konczykowski and Vadim B. Geshkenbein

doi:10.1038/35018532

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Optimal shapes of compact strings p287

Amos Maritan, Cristian Micheletti, Antonio Trovato and Jayanth R. Banavar

doi:10.1038/35018538

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See also: News and Views by Stasiak & Maddocks

Evidence for a link between global lightning activity and upper tropospheric water vapour p290

Colin Price

doi:10.1038/35018543

First paragraph | Full Text | PDF (239K)

See also: News and Views by Soden

Melting of the Earth's lithospheric mantle inferred from protactinium– thorium–uranium isotopic data p293

Yemane Asmerom, Hai Cheng, Rebecca Thomas, Marc Hirschmann and R. Lawrence Edwards

doi:10.1038/35018550

First paragraph | Full Text | PDF (263K)

Female bluethroats enhance offspring immunocompetence through extra-pair copulations p296

Arild Johnsen, Vegard Andersen, Christine Sunding and Jan T. Lifjeld

doi:10.1038/35018556

First paragraph | Full Text | PDF (181K)

Magnetite defines a vertebrate magnetoreceptor p299

Carol E. Diebel, Roger Proksch, Colin R. Green, Peter Neilson and Michael M. Walker

doi:10.1038/35018561

First paragraph | Full Text | PDF (288K)

Transformation from temporal to rate coding in a somatosensory thalamocortical pathway p302

Ehud Ahissar, Ronen Sosnik and Sebastian Haidarliu

doi:10.1038/35018568

First paragraph | Full Text | PDF (256K) | Supplementary information

See also: News and Views by Diamond

Presenilin is required for proper morphology and function of neurons in C. elegans p306

Nicole Wittenburg, Stefan Eimer, Bernard Lakowski, Sascha Röhrig, Claudia Rudolph and Ralf Baumeister

doi:10.1038/35018575

First paragraph | Full Text | PDF (215K)

A chemokine-driven positive feedback loop organizes lymphoid follicles p309

K. Mark Ansel, Vu N. Ngo, Paul L. Hyman, Sanjiv A. Luther, Reinhold Förster, Jonathon D. Sedgwick, Jeffrey L. Browning, Martin Lipp and Jason G. Cyster

doi:10.1038/35018581

First paragraph | Full Text | PDF (611K)

A tertiary interaction that links active-site domains to the 5' splice site of a group II intron p315

Marc Boudvillain, Alexandre de Lencastre and Anna Marie Pyle

doi:10.1038/35018589

First paragraph | Full Text | PDF (205K) | Supplementary information

A ratchet-like inter-subunit reorganization of the ribosome during translocation p318

Joachim Frank and Rajendra Kumar Agrawal

doi:10.1038/35018597

First paragraph | Full Text | PDF (326K) | Supplementary information

Mimicry of ice structure by surface hydroxyls and water of a -helix antifreeze protein p322

Yih-Cherng Liou, Ante Tocilj, Peter L. Davies and Zongchao Jia

doi:10.1038/35018604

First paragraph | Full Text | PDF (242K)

-Helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect p325

Steffen P. Graether, Michael J. Kuiper, Stéphane M. Gagné, Virginia K. Walker, Zongchao Jia, Brian D. Sykes and Peter L. Davies

doi:10.1038/35018610

First paragraph | Full Text | PDF (348K)

New on the Market

Counting on proteomics p329

Download a trial of image analysis software, and seek those proteins.

doi:10.1038/35018645

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