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Volume 405 Issue 6785, 25 May 2000

Opinion

  • US astronomers are getting better at forming a collective view of priorities. Their latest wish list is worth fighting for, but it is the process used to generate it that gives the community the best chance of attracting the necessary funds.

    Opinion

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  • A new set of prizes is an apt celebration of the significance and wonder to be found in pure mathematics.

    Opinion
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News

  • Paris

    France is to create a ‘grande école’ dedicated to Internet professionals, the country's Prime Minister, Lionel Jospin, announced last week.

    • Heather McCabe
    News
  • London

    Keen to promote a single European astronomy organization, Britain is opening negotiations about possible membership of the European Southern Observatory.

    • David Dickson
    • Alison Abbott
    News
  • Paris.

    The idea that most of the primary scientific literature should be available for free in electronic form has gained some heavyweight support from 10 leading biomedical researchers.

    • Declan Butler
    News
  • Moscow

    Russian science appears to have a friend in the country's new prime minister, at least in principle.

    • Carl Levitin
    News
  • Washington

    Frustrated advocates of action to alleviate global warming won a valuable new ally last week when US Senator John McCain held a hearing highlighting warnings that human activities play a significant role in global warming.

    • Colin Macilwain
    News
  • Paris

    France's biomedical research agency, INSERM, has clashed with some of its research staff over an ambitious proposal to build a multi-million dollar centre for physiology research outside Paris.

    • Heather McCabe
    News
  • Baltimore

    Robert Gallo, director of the Institute of Human Virology in Baltimore, Maryland, last week unveiled plans to test a novel AIDS vaccine within the next two years.

    • Paul Smaglik
    News
  • Canberra

    Australian researchers have been upset to learn they are being expected to help the government make hundreds of millions of dollars in ‘savings’ through a cut in funding to research grant recipients.

    • Peter Pockley
    News
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News in Brief

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News Feature

  • Allan Bradley is to head the Sanger Centre, a powerhouse of the Human Genome Project. Trisha Gura asks how he will meet the challenges.

    • Trisha Gura
    News Feature
  • North America is about to come under intense geophysical scrutiny. Rex Dalton explains how the four projects known as EarthScope will advance our understanding of volcanoes, fault systems and earthquakes.

    • Rex Dalton
    News Feature
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Correspondence

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Book Review

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Millennium Essay

  • Modern physics bears the imprint of Western and Asian philosophies.

    • Susantha Goonatilake
    Millennium Essay
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Futures

  • The apocalypse: a great day out for the whole family.

    • Joe Haldeman
    Futures
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News & Views

  • The snowball Earth hypothesis posits an ice-covered planet. New climate simulations of ‘snowball’ conditions allow ice-free equatorial oceans that may be crucial for a theory about early animal evolution.

    • Bruce Runnegar
    News & Views
  • ATM and NBS1 are genes that are mutated in two different human diseases. Cells from patients with these diseases show similarities, including increased chromosome breakage, so ATM and NBS1 might work together in DNA repair. Indeed, ATM phosphorylates NBS1 in several places — events needed for the cellular response to DNA breaks.

    • Jean Y. J. Wang
    News & Views
  • To the eye, most stars seem to be single, like our Sun, but in fact about half are binary or multiple systems. Now a newly accepted theory of star formation — fragmentation — that explains the formation of binary systems makes it unlikely that single stars will harbour planets. Binary stars may be more hospitable.

    • Alan P. Boss
    News & Views
  • Imprinted genes, such as the closely linked genesH19 and Igf2, are expressed from either the maternal or the paternal chromosome, but not both. A newly discovered mechanism for ‘silencing’ the Igf2 gene on the maternal chromosome involves an ‘insulator’ region found upstream of H19.

    • Wolf Reik
    • Adele Murrell
    News & Views
  • The degree of rotation of the Earth's inner core relative to the mantle has been under study for several years, the techniques concerned becoming ever more refined. The best resolution yet comes from a method involving seismic waves scattered by the core: the answer it gives is 0.15° per year.

    • Henri-Claude Nataf
    News & Views
  • Over the past decade there has been a surge of studies on ocean biogeochemistry, and the carbon cycle in particular. The results were the central topic of a meeting in April, one message being that it is the biological aspects of the oceanic carbon cycle that are the trickiest to quantify.

    • Jim Gillon
    News & Views
  • Carefully engineered systems sometimes fail catastrophically despite the best intentions of their designers. A new theory called ‘highly optimized tolerance’ attempts to explain how this happens.

    • Mark Newman
    News & Views
  • The regulation of synaptic plasticity by neuronal activity is thought to underlie learning and memory. A new way of altering synaptic properties in response to activity involves changes in the composition and function of AMPA-type receptors for the neurotransmitter glutamate.

    • Christine R. Rose
    • Arthur Konnerth
    News & Views
  • The use of photons for information transmission in part depends on creating the appropriate circuitry. Photonic crystals for the control and routing of optical signals could be used as one component of such circuits. An innovative way of fabricating these crystals involving artificial opal and silicon provides a promising route forward.

    • Karen Southwell
    News & Views
  • Cockayne syndrome is a rare, inherited human disease that can arise from mutations in any one of five genes, involved in different aspects of DNA repair. New results have now led to a model for how all of these different mutations result in the same disease.

    • Philip C. Hanawalt
    News & Views
  • Underwater creatures have devised several ways for working out how deep they are. Daedalus reckons one unexplored method may be the unfolding of proteins at increased pressures, or depths. Such ‘barometric enzymes’ may throw light on the problem of protein folding.

    • David Jones
    News & Views
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Brief Communication

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Progress

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Article

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Letter

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New on the Market

  • Top tips, filter tips, ergonomic tips and other takes on liquid handling.

    New on the Market
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