Table of contents


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Opinion

Rules of genome access p317

Statements by presidents of countries and societies highlight the concern that human genome data be publicly accessible, and quickly. The devil may lie in the emerging terms of public access to privately owned databases.

doi:10.1038/35006211


Eyes, ears and science p317

Two artists have succeeded in involving two or more senses to produce something special.

doi:10.1038/35006213


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News

Researchers caught in dispute over transgenic mice patents p319

Rex Dalton

doi:10.1038/35006215


Iridium crash relieves astronomers p319

Alison Abbott

doi:10.1038/35006219


Computer glitch unleashes prize nomination debate p320

Steve Nadis

doi:10.1038/35006221


Japan's cloning ban will still allow stem cell experiments p321

Robert Triendl

doi:10.1038/35006223


Space researchers protest at 'disruptive' export controls p321

Tony Reichhardt

doi:10.1038/35006225


Car maker joins exodus from anti-Kyoto coalition p322

Meredith Wadman

doi:10.1038/35006228


Could AIDS treatments slip through patents loophole? p322

Paul Smaglik

doi:10.1038/35006230


Israeli R&D grants 'too restrictive' p322

Haim Watzman

doi:10.1038/35006232


Northern lobby attacks UK synchrotron siting p323

Natasha Loder

doi:10.1038/35006234


French minister feels the heat over Soleil p323

Heather McCabe

doi:10.1038/35006237


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News Analysis

US/UK statement on genome data prompts debate on 'free access' p324

The genomics company Celera is about to release the terms of access to its human genome data. Many will be reassured. But concerns remain.

Declan Butler

doi:10.1038/35006239


Japan may place gene research on summit agenda p324

Asako Saegusa

doi:10.1038/35006243


'The human genome itself must be freely available to all humankind' p325

Bruce Alberts and Sir Aaron Klug

doi:10.1038/35006245


News in brief p326

doi:10.1038/35006247


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Correspondence

To create generalists, teach students how to learn by themselves p329

Philippe Baveye

doi:10.1038/35006249


We have touched the dust from dying stars p329

Donald D. Clayton

doi:10.1038/35006251


Confusion over cash for Indian biotech centre... p329

V. S. Chauhan

doi:10.1038/35006253


... though funding states have promised to pay up p329

Arturo Falaschi

doi:10.1038/35006255


The lasting value of Mitchell's mechanisms p330

John Prebble

doi:10.1038/35006257


People must be judged in the context of their time p330

Ulrich Wobus and Ingo Schubert

doi:10.1038/35006259


reply: ... though funding states have promised to pay up p330

K.S. Jayaraman

doi:10.1038/35006265


reply: People must be judged in the context of their time p330

Susanne Heim

doi:10.1038/35006267


Top

Book Reviews

The imperial slaughterhouse p331

Literature and the toll paid for the subjugation of the British Empire.

Roy Porter reviews Romanticism and Colonial Disease by Alan Bewell

doi:10.1038/35006142


A meteorologist's nightmare p332

Howard B. Bluestein reviews Isaac's Storm by Erik Larson

doi:10.1038/35006145


New in paperback p332

doi:10.1038/35006148


Life on the large side p333

doi:10.1038/35006150


Palaeobiology in mammoth form p333

Michael J. Benton reviews Encyclopedia of Paleontology, Volumes I & II

doi:10.1038/35006153


Science in culture p334

Martin Kemp reviews

doi:10.1038/35006155


Top

Millennium Essay

Brains, courage and integrity p335

Gandhi and Sakharov set us an inspiring example for the twenty-first century

Tom Gehrels

doi:10.1038/35006261


Top

Futures

Bordeaux Mixture p337

If at first you can't convince people about the benefits of GM crops — cheat.

Charles Dexter Ward

doi:10.1038/35006178


Top

News and Views

Human evolution: From forelimbs to two legs p339

A reanalysis of the wrist bones of early human fossils provides the first good evidence that humans evolved from ancestors who 'knuckle-walked', as chimps and gorillas do today.

Mark Collard and Leslie C. Aiello

doi:10.1038/35006181


Quantum optics: Tricks with a single photon p340

Peter Zoller

doi:10.1038/35006185


Neurodegenerative diseases: Parkinson's pathology in a fly p341

Christian Haass and Philipp J. Kahle

doi:10.1038/35006188


Gamma-ray astronomy: A needle in a cosmic haystack p344

Isabelle A. Grenier

doi:10.1038/35006191


X-ray optics: Making hard light sharper p345

Roland Smith

doi:10.1038/35006194


100 and 50 years ago p345

doi:10.1038/35006198


Membrane fusion: Changing partners p347

Chavela M. Carr and Peter J. Novick

doi:10.1038/35006200


Cell biology: Rafting vesicle p348

Amanda Tromans

doi:10.1038/35006203


Daedalus: Natural cunning p349

David Jones

doi:10.1038/35006206


Obituary: Robert Rathbun Wilson (1914–2000) p350

Alvin V. Tollestrup

doi:10.1038/35006208


Top

Brief Communications

Y-chromosome variation and Irish origins p351

A pre-neolithic gene gradation starts in the near East and culminates in western Ireland.

Emmeline W. Hill, Mark A. Jobling and Daniel G. Bradley

doi:10.1038/35006158


Critical phenomena: Fluctuations caught in the act p352

Lars K. Nielsen, Thomas Bjørnholm and Ole G. Mouritsen

doi:10.1038/35006162


Alzheimer's disease: Apolipoprotein E and cognitive performance p352

Jacob Raber, Derek Wong, Gui-Qiu Yu, Manuel Buttini, Robert W. Mahley, Robert E. Pitas and Lennart Mucke

doi:10.1038/35006165


Environmental microbiology: A tetrodotoxin-producing marine pathogen p354

Kim B. Ritchie, Ivan Nagelkerken, Sara James and Garriet W. Smith

doi:10.1038/35006168


Top

Article

Three-dimensional structure of the neuronal-Sec1–syntaxin 1a complex p355

Kira M. S. Misura, Richard H. Scheller and William I. Weis

doi:10.1038/35006120

See also: News and Views by Carr & Novick


Top

Letters to Nature

Discovery of a new population of high-energy bold gamma-ray sources in the Milky Way p363

N. Gehrels, D. J. Macomb, D. L. Bertsch, D. J. Thompson and R. C. Hartman

doi:10.1038/35006001

See also: News and Views by Grenier


Trapping an atom with single photons p365

P. W. H. Pinkse, T. Fischer, P. Maunz and G. Rempe

doi:10.1038/35006006

See also: News and Views by Zoller


An algorithmic benchmark for quantum information processing p368

E. Knill, R. Laflamme, R. Martinez and C.-H. Tseng

doi:10.1038/35006012


Storage of X-ray photons in a crystal resonator p371

K.-D. Liss, R. Hock, M. Gomm, B. Waibel, A. Magerl, M. Krisch and R. Tucoulou

doi:10.1038/35006017

See also: News and Views by Smith


Soft-mode hardening in SrTiO3 thin films p373

A. A. Sirenko, C. Bernhard, A. Golnik, Anna M. Clark, Jianhua Hao, Weidong Si and X. X. Xi

doi:10.1038/35006023


Extended surface chirality from supramolecular assemblies of adsorbed chiral molecules p376

M. Ortega Lorenzo, C. J. Baddeley, C. Muryn and R. Raval

doi:10.1038/35006031


Bonding and reactivity at oxide mineral surfaces from model aqueous complexes p379

Brian L. Phillips, William H. Casey and Magnus Karlsson

doi:10.1038/35006036


Evidence that humans evolved from a knuckle-walking ancestor p382

Brian G. Richmond and David S. Strait

doi:10.1038/35006045

See also: News and Views by Collard & Aiello


Predictive accuracy of population viability analysis in conservation biology p385

Barry W. Brook, Julian J. O'Grady, Andrew P. Chapman, Mark A. Burgman, H. Resit Akçakaya and Richard Frankham

doi:10.1038/35006050


Low variability in a Y-linked plant gene and its implications for Y-chromosome evolution p388

Dmitry A. Filatov, Françoise Monéger, Ioan Negrutiu and Deborah Charlesworth

doi:10.1038/35006057


Representation of a perceptual decision in developing oculomotor commands p390

Joshua I. Gold and Michael N. Shadlen

doi:10.1038/35006062


A Drosophila model of Parkinson's disease p394

Mel B. Feany and Welcome W. Bender

doi:10.1038/35006074

See also: News and Views by Haass & Kahle


Interleukin-1 polymorphisms associated with increased risk of gastric cancer p398

Emad M. El-Omar, Mary Carrington, Wong-Ho Chow, Kenneth E. L. McColl, Jay H. Bream, Howard A. Young, Jesus Herrera, Jolanta Lissowska, Chiu-Chin Yuan, Nathaniel Rothman, George Lanyon, Maureen Martin, Joseph F. Fraumeni, Jr and Charles S. Rabkin

doi:10.1038/35006081


PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes p402

Zuoming Sun, Christopher W. Arendt, Wilfried Ellmeier, Edward M. Schaeffer, Mary Jean Sunshine, Leena Gandhi, Justin Annes, Daniela Petrzilka, Abraham Kupfer, Pamela L. Schwartzberg and Dan R. Littman

doi:10.1038/35006090


Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1 p407

Long Gu, Susan Tseng, Renée M. Horner, Carmen Tam, Massimo Loda and Barrett J. Rollins

doi:10.1038/35006097


Betaglycan binds inhibin and can mediate functional antagonism of activin signalling p411

Kathy A. Lewis, Peter C. Gray, Amy L. Blount, Leigh A. MacConell, Ezra Wiater, Louise M. Bilezikjian and Wylie Vale

doi:10.1038/35006129


The Gcn5 bromodomain co-ordinates nucleosome remodelling p414

Popi Syntichaki, Irene Topalidou and George Thireos

doi:10.1038/35006136


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New on the Market

We have the biotechnology p419

From insects to FISH, more from companies with designs on your lab space.

doi:10.1038/35006171


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