Table of contents


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Opinion

Dutch cuts ahead p403

The new government of the Netherlands should reverse rather than exacerbate its declining support for basic science — a message reinforced by the OECD.

doi:10.1038/28680


A word in your ear p403

As the conference season approaches, it is time to reflect on the negative effects of ill-prepared presentations.

doi:10.1038/28682


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News

Dutch universities and research laboratories set for major cuts p405

Declan Butler

doi:10.1038/28684


Hubble homes in on the birth of bright stars p405

doi:10.1038/28686


China and Taiwan edge a shade closer p406

David Dickson

doi:10.1038/28689


New Zealand government backtracks on funding promises p406

Peter Pockley

doi:10.1038/28691


Ministers block disposal of oil rigs at sea p407

Ehsan Masood

doi:10.1038/28694


Meeting agrees cuts to radioactive emissions p407

Ehsan Masood

doi:10.1038/28697


Cloned mice fail to rekindle ethics debate p408

Meredith Wadman

doi:10.1038/28699


Japanese fear that new publicity rules could hinder their research p408

Asako Saegusa

doi:10.1038/28702


Mother bears could help save giant panda p409

Asako Saegusa

doi:10.1038/28704


Patent clash looming over cloning techniques? p409

Declan Butler

doi:10.1038/28706


Alarm in US over database antipiracy bill p410

Tony Reichhardt

doi:10.1038/28709


Telescopes track down lost spacecraft p410

Alison Abbott

doi:10.1038/28712


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News Analysis

A physicist joins the race for Congress p411

There are only three scientists in Congress, but Rush Holt, former assistant director of the Princeton Plasma Physics Laboratory, believes he can become the fourth. He comfortably won the primary to become the Democrat nominee in New Jersey's twelfth district.

Colin Macilwain

doi:10.1038/28714


News in Brief p412

doi:10.1038/28717


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Correspondence

Japan to the fore in biodiversity initiative p413

Junko Shimura

doi:10.1038/28719


Extrasensory statistics p413

Dean Radin and I. J. Good

doi:10.1038/28721


Tough time for taxonomy p413

Marcel Jaspars

doi:10.1038/28723


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Commentary

How to simplify the plutonium problem p415

The global stockpile of separated plutonium is expensive and hazardous to reprocess, vulnerable to terrorist threat and disposal is costly. But there are apparently simple ways to reduce this problem.

doi:10.1038/28725


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News and Views

A sense for landmines p417

Anthony W. Czarnik

doi:10.1038/28728


Ecology:  A declining amphibian conundrum p418

Tim Halliday

doi:10.1038/28732


Superconductivity:  Strain yourself p419

Ivan K. Schuller

doi:10.1038/28735


Immunology:  The original sin of killer T cells p421

Andrew J. McMichael

doi:10.1038/28738


Palaeoclimatology:  The ends of an era p422

Christopher Charles

doi:10.1038/28741


Marine biology:  Sex and the single copepod p423

Rory Howlett

doi:10.1038/28743


Ecology:  Polarized flight p425

Alison Mitchell

doi:10.1038/28747


100 and 50 years ago p426

doi:10.1038/28750


Vesicular transport:  Sticky fingers grab a lipid p426

Claudia Wiedemann and Shamshad Cockcroft

doi:10.1038/28752


Drug delivery:  A lesson from secretory granules p427

Ronald A. Siegel

doi:10.1038/28756


Daedalus:  A chance of justice p428

David Jones

doi:10.1038/28758


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Science and Image

Kroto and charisma p429

A vision of a dome led to the naming of buckminsterfullerene. This carbon cluster has become an icon for chemistry, thanks to the media-friendly appeal it shares with co-discoverer Sir Harry Kroto.

Martin Kemp

doi:10.1038/28760


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Scientific Correspondence

Ploughing up the wood-wide web? p431

T. Helgason, T. J. Daniell, R. Husband, A. H. Fitter and J. P. W. Young

doi:10.1038/28764


FYVE fingers bind PtdIns(3)P p432

Jean-Michel Gaullier, Anne Simonsen, Antonello D'Arrigo, Bjørn Bremnes, Harald Stenmark and Rein Aasland

doi:10.1038/28767

See also: News and Views by Wiedemann & Cockcroft


A functional PtdIns(3)P-binding motif p433

Varsha Patki, Deirdre C. Lawe, Silvia Corvera, Joseph V. Virbasius and Anil Chawla

doi:10.1038/28771

See also: News and Views by Wiedemann & Cockcroft


Does practice shape the brain? p434

Pat Monaghan, Neil B. Metcalfe and Graeme D. Ruxton

doi:10.1038/28775


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Film Review

Rocky horror picture shows p435

Kevin Zahnle reviews Deep Impact and Armageddon

doi:10.1038/28777


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Book Reviews

The weeds in Fibonacci's garden p436

Dennis Bray

doi:10.1038/28781


Bouffi à la girafe p437

Philippe Janvier

doi:10.1038/28785


The is and the ought p437

Brian Martin

doi:10.1038/28788


The FAQs of astronomy p438

Jay M. Pasachoff

doi:10.1038/28790


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Review

Gaia and natural selection p439

Timothy M. Lenton

doi:10.1038/28792


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Letters to Nature

An extraordinary cluster of massive stars near the centre of the Milky Way p448

E. Serabyn, D. Shupe and D. F. Figer

doi:10.1038/28799


Self-organized growth of nanostructure arrays on strain-relief patterns p451

Harald Brune, Marcella Giovannini, Karsten Bromann and Klaus Kern

doi:10.1038/28804


Doubling the critical temperature of La1.9Sr0.1CuO4 using epitaxial strain p453

J.-P. Locquet, J. Perret, J. Fompeyrine, E. Mächler, J. W. Seo and G. Van Tendeloo

doi:10.1038/28810

See also: News and Views by Schuller


Nanocomposite polymer electrolytes for lithium batteries p456

F. Croce, G. B. Appetecchi, L. Persi and B. Scrosati

doi:10.1038/28818


A synthetic mimic of the secretory granule for drug delivery p459

Patrick F. Kiser, Glynn Wilson and David Needham

doi:10.1038/28822

See also: News and Views by Siegel


Budgetary and biogeochemical implications of N2O isotope signatures in the Arabian Sea p462

S. W. A. Naqvi, T. Yoshinari, D. A. Jayakumar, M. A. Altabet, P. V. Narvekar, A. H. Devol, J. A. Brandes and L. A. Codispoti

doi:10.1038/28828


Orbital modulation of the Earth's magnetic field intensity p464

J. E. T. Channell, D. A. Hodell, J. McManus and B. Lehman

doi:10.1038/28833


Energy and trace-gas fluxes across a soil pH boundary in the Arctic p469

D. A. Walker, N. A. Auerbach, J. G. Bockheim, F. S. Chapin, III, W. Eugster, J. Y. King, J. P. McFadden, G. J. Michaelson, F. E. Nelson, W. C. Oechel, C. L. Ping, W. S. Reeburg, S. Regli, N. I. Shiklomanov and G. L. Vourlitis

doi:10.1038/28839


Complementarity and the use of indicator groups for reserve selection in Uganda p472

Peter C. Howard, Paolo Viskanic, Tim R. B. Davenport, Fred W. Kigenyi, Michael Baltzer, Chris J. Dickinson, Jeremiah S. Lwanga, Roger A. Matthews and Andrew Balmford

doi:10.1038/28843


Membrane potential synchrony of simultaneously recorded striatal spiny neurons in vivo p475

Edward A. Stern, Dieter Jaeger and Charles J. Wilson

doi:10.1038/28848


Glutamate locally activates dendritic outputs of thalamic interneurons p478

Charles L. Cox, Qiang Zhou and S. Murray Sherman

doi:10.1038/28855


Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes p482

Paul Klenerman and Rolf M. Zinkernagel

doi:10.1038/28860

See also: News and Views by McMichael


Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis p485

Peter Carmeliet, Yuval Dor, Jean-Marc Herbert, Dai Fukumura, Koen Brusselmans, Mieke Dewerchin, Michal Neeman, Françoise Bono, Rinat Abramovitch, Patrick Maxwell, Cameron J. Koch, Peter Ratcliffe, Lieve Moons, Rakesh K. Jain, Désiré Collen and Eli Keshet

doi:10.1038/28867


Role of citron kinase as a target of the small GTPase Rho in cytokinesis p491

Pascal Madaule, Masatoshi Eda, Naoki Watanabe, Kazuko Fujisawa, Toshiyuki Matsuoka, Haruhiko Bito, Toshimasa Ishizaki and Shuh Narumiya

doi:10.1038/28873


EEA1 links PI(3)K function to Rab5 regulation of endosome fusion p494

Anne Simonsen, Roger Lippe, Savvas Christoforidis, Jean-Michel Gaullier, Andreas Brech, Judy Callaghan, Ban-Hock Toh, Carol Murphy, Marino Zerial and Harald Stenmark

doi:10.1038/28879

See also: News and Views by Wiedemann & Cockcroft


Transcriptional activators direct histone acetyltransferase complexes to nucleosomes p498

Rhea T. Utley, Keiko Ikeda, Patrick A. Grant, Jacques Côté, David J. Steger, Anton Eberharter, Sam John and Jerry L. Workman

doi:10.1038/28886


Structure of the metal-ion-activated diphtheria toxin repressor/ tox operator complex p502

André White, Xiaochun Ding, Johanna C. vanderSpek, John R. Murphy and Dagmar Ringe

doi:10.1038/28893


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New on the Market

A light at the end of the tube p507

This assortment of products includes laser beam attenuators, motorized steppers and translators, laser confocal microscopy systems, beam analysers, as well as infrared and diode laser bars and systems.

compiled by Brendan Horton from information provided by the manufacturers.

doi:10.1038/28900


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