Opinion

Timely lessons in investment from a wealthy 'wonk' p517

President Bill Clinton's budget proposal contains an important message for governments that are tempted to undervalue basic science, its crucible, the research university, and the importance of impartial peer review.

doi:10.1038/35195

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News

French ministry reopens inquiry into conduct of INSERM unit p519

Declan Butler and Olivier De Gandt

doi:10.1038/35197

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Spain blocks new Framework programme p519

Alison Abbott

doi:10.1038/35200

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New Hubble institute chief seeks broader focus and more work p520

Tony Reichhardt

doi:10.1038/35202

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NSF returns to favour with biggest increase p521

Colin Macilwain

doi:10.1038/35205

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NASA cuts Earth observation, boosts 'gravitational biology' p521

Tony Reichhardt

doi:10.1038/35207

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Biomedical research shines in Clinton budget bonanza p521

Colin Macilwain

doi:10.1038/35209

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Global warming is bright spot for Energy p522

Colin Macilwain

doi:10.1038/35212

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NIH basks in broad support p522

Meredith Wadman

doi:10.1038/35214

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EPA to spend more on clean air and water p522

doi:10.1038/35216

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Disaster network boost in increase for USGS p522

doi:10.1038/35218

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Technology projects fall from presidential grace p522

doi:10.1038/35220

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UK consults public on clones for research p523

David Dickson

doi:10.1038/35222

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US sees flurry of bills in bids to legislate p523

Meredith Wadman

doi:10.1038/35224

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News Analysis

Latin America steps up its science tempo p524

Democracy, price stability and economic liberalization in Latin America are combining to present scientists in the region with their best opportunity in decades to match international standards of excellence.

Colin Macilwain

doi:10.1038/35227

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'Collaboration could restore excellence' p524

Colin Macilwain

doi:10.1038/35230

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Argentina gives peer review a boost p525

Colin Macilwain

doi:10.1038/35232

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News in Brief p526

doi:10.1038/35235

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News

correction p527

doi:10.1038/35435

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Correspondence

Place of science on European agenda p528

Maurice Guéron

doi:10.1038/35239

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Order and justice in French universities p528

A. D. Strosberg

doi:10.1038/35241

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Risk and benefit p528

Tom Crompton, John Barrett, Chris Gliddon, Julian Kinderlerer and George Tzotzos

doi:10.1038/35243

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News and Views

Animal embryos in deep time p529

Stefan Bengtson

doi:10.1038/35245

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Marine colloids:  A neglected dimension p530

Mark L. Wells

doi:10.1038/35248

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Immunodeficiency viruses:  1959 and all that p531

Simon Wain-Hobson

doi:10.1038/35251

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Nanocrystals:  The strongest size p532

Sidney Yip

doi:10.1038/35254

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Transcriptional repression:  The cancer-chromatin connection p533

Ronald A. DePinho

doi:10.1038/35257

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100 and 50 years ago p535

doi:10.1038/35260

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Carbon cycle:  Feedbacks from the sea floor p536

Clare E. Reimers

doi:10.1038/35262

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Human genetics:  Hair apparent p537

Kevin Davies

doi:10.1038/35264

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Materials science:  Disciplines bound by pressure p539

Paul F. McMillan

doi:10.1038/35267

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Exhibition:  Natural attraction p540

Tim Lincoln

doi:10.1038/35271

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Telemicroscopy:  Net progress p540

Kevin Burton and Daniel L. Farkas

doi:10.1038/35274

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Daedalus:  The seeing ear p541

David Jones

doi:10.1038/35277

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Obituary:  Vladimir Prelog (1906-98) p542

Jack D. Dunitz

doi:10.1038/35279

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Art and Science

Onwin's holistics p543

Crystals forming on a sea of brine in one of Glen Onwin's installations demonstrated the emergence of shape from chaos — and reflected the artist's interest in the origins of matter.

Martin Kemp

doi:10.1038/35282

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Scientific Correspondence

Worms bask in extreme temperatures p545

S. C. Cary, T. Shank and J. Stein

doi:10.1038/35286

First paragraph | Full Text | PDF (416K)

Phytoplankton change in the North Atlantic p546

Philip C. Reid, Martin Edwards, Harold G. Hunt and Andrew J. Warner

doi:10.1038/35290

First paragraph | Full Text | PDF (287K)

Language steamrollers? p547

John Edward Terrell, John Hines, Terry L. Hunt, Chapurukha Kusimba and Carl Lipo

doi:10.1038/35294

First paragraph | Full Text | PDF (92K)

Language steamrollers? p547

Wolfgang E. Sterrer

doi:10.1038/35296

First paragraph | Full Text | PDF (92K)

Reply:  Language steamrollers? p547

Jared Diamond

doi:10.1038/35298

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Paraflagellar rod is vital for trypanosome motility p548

Philippe Bastin, Trevor Sherwin and Keith Gull

doi:10.1038/35300

First paragraph | Full Text | PDF (137K)

Book Reviews

The story of ewe, again p549

Robert Bud reviews Clone: The Road to Dolly and the Path Ahead by Gina Kolata

doi:10.1038/35304

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The shell of Aphrodite p550

doi:10.1038/35307

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Homage to Earth p550

Peter Westbroek reviews Gaia's Body: Toward a Physiology of Earth by Tyler Volk

doi:10.1038/35310

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New in Paperback p551

doi:10.1038/35312

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Probing the sea p552

N. G. Carr reviews Molecular Approaches to the Study of the Ocean edited by Keith E. Cooksey

doi:10.1038/35314

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Patchy coverage p552

Thomas F. Stocker reviews Climate Process and Change by Edward Bryant

doi:10.1038/35316

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Article

Three-dimensional preservation of algae and animal embryos in a Neoproterozoic phosphorite p553

Shuhai Xiao, Yun Zhang and Andrew H. Knoll

doi:10.1038/35318

Abstract | Full Text | PDF (1,979K)

See also: News and Views by Bengtson

Letters to Nature

A stellar origin for the short-lived nuclides in the early Solar System p559

S. Sahijpal, J. N. Goswami, A. M. Davis, L. Grossman and R. S. Lewis

doi:10.1038/35325

First paragraph | Full Text | PDF (215K)

Softening of nanocrystalline metals at very small grain sizes p561

Jakob Schiøtz, Francesco D. Di Tolla and Karsten W. Jacobsen

doi:10.1038/35328

First paragraph | Full Text | PDF (589K)

See also: News and Views by Yip

Compound refractive optics for the imaging and focusing of low-energy neutrons p563

M. R. Eskildsen, P. L. Gammel, E. D. Isaacs, C. Detlefs, K. Mortensen and D. J. Bishop

doi:10.1038/35333

First paragraph | Full Text | PDF (555K)

Chiral discrimination by chemical force microscopy p566

Rachel McKendry, Maria-Elena Theoclitou, Trevor Rayment and Chris Abell

doi:10.1038/35339

First paragraph | Full Text | PDF (241K)

Spontaneous assembly of marine dissolved organic matter into polymer gels p568

Wei-Chun Chin, Mónica V. Orellana and Pedro Verdugo

doi:10.1038/35345

First paragraph | Full Text | PDF (311K)

See also: News and Views by Wells

Influence of oxygen exposure time on organic carbon preservation in continental margin sediments p572

Hilairy E. Hartnett, Richard G. Keil, John I. Hedges and Allan H. Devol

doi:10.1038/35351

First paragraph | Full Text | PDF (230K)

See also: News and Views by McMillan

Oceanic transport of subpolar climate signals to mid-depth subtropical waters p575

Ruth G. Curry, Michael S. McCartney and Terrence M. Joyce

doi:10.1038/35356

First paragraph | Full Text | PDF (322K)

The generation of plankton patchiness by turbulent stirring p577

Edward R. Abraham

doi:10.1038/35361

First paragraph | Full Text | PDF (374K)

Collinear stimuli regulate visual responses depending on cell's contrast threshold p580

Uri Polat, Keiko Mizobe, Mark W. Pettet, Takuji Kasamatsu and Anthony M. Norcia

doi:10.1038/35372

First paragraph | Full Text | PDF (378K)

Pathogenesis of two axonopathies does not require axonal neurofilaments p584

J. Eyer, D. W. Cleveland, P. C. Wong and A. C. Peterson

doi:10.1038/35378

First paragraph | Full Text | PDF (609K)

Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants p587

Florence F. Davidson and Hermann Steller

doi:10.1038/35385

First paragraph | Full Text | PDF (871K)

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells p591

Volker Henn, Joseph R. Slupsky, Michael Gräfe, Ioannis Anagnostopoulos, Reinhold Förster, Gert Müller-Berghaus and Richard A. Kroczek

doi:10.1038/35393

First paragraph | Full Text | PDF (331K)

An African HIV-1 sequence from 1959 and implications for the origin of the epidemic p594

Tuofu Zhu, Bette T. Korber, Andre J. Nahmias, Edward Hooper, Paul M. Sharp and David D. Ho

doi:10.1038/35400

First paragraph | Full Text | PDF (233K)

See also: News and Views by Wain-Hobson

Retinoblastoma protein recruits histone deacetylase to repress transcription p597

Alexander Brehm, Eric A. Miska, Dennis J. McCance, Juliet L. Reid, Andrew J. Bannister and Tony Kouzarides

doi:10.1038/35404

First paragraph | Full Text | PDF (313K)

See also: News and Views by DePinho

Retinoblastoma protein represses transcription by recruiting a histone deacetylase p601

L. Magnaghi-Jaulin, R. Groisman, I. Naguibneva, P. Robin, S. Lorain, J. P. Le Villain, F. Troalen, D. Trouche and A. Harel-Bellan

doi:10.1038/35410

First paragraph | Full Text | PDF (354K)

See also: News and Views by DePinho

The conduction pore of a cardiac potassium channel p605

Kwok-Keung Tai and Steve A. N. Goldstein

doi:10.1038/35416

First paragraph | Full Text | PDF (303K)

Design of potent selective zinc-mediated serine protease inhibitors p608

Bradley A. Katz, James M. Clark, Janet S. Finer-Moore, Thomas E. Jenkins, Charles R. Johnson, Michael J. Ross, Christine Luong, William R. Moore and Robert M. Stroud

doi:10.1038/35422

First paragraph | Full Text | PDF (428K)

Techniques and Technology

Telemicroscopy via the Internet p613

We report a concept that is not only applicable for telemicroscopy, but may be adapted for the remote control of any kind of scientific device, opening a new field of application for the Internet.

Guenter Wolf, Detlev Petersen, Manfred Dietel and Iver peterson

doi:10.1038/35429

Full Text | PDF (549K)

See also: News and Views by Burton & Farkas

New on the Market

New on the market p615

Tools for riding the biotechnology wave, including those for designing, synthesizing, analysing and predicting the efficacy of new compounds.
compiled by Brendan Horton from information provided by the manufacturers. For more details, fill in the reader service card bound inside the journal.

doi:10.1038/35433

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