Abstract
Nicotine in cigar smoke (pH 8.5) is much more readily absorbed through the mucous membranes of the mouth than is nicotine in cigarette smoke (pH 5.3) because there is a higher concentration of unionized nicotine in the relatively alkaline cigar smoke.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Armitage, A. K., Brit. J. Pharmacol., 25, 515 (1965).
Armitage, A. K., Hall, G. H., and Morrison, C. F., Nature, 217, 331 (1968).
Kershbaum, A., Bellet, S., Hirabayashi, M., Feinberg, N. J., and Eilberg, R., Arch. Intern. Med., 120, 311 (1967).
Armitage, A. K., Hall, G. H., and Heneage, E., Brit. J. Pharmacol., 36, 211 (1969).
Armitage, A. K., Milton, A. S., and Morrison, C. F., Brit. J. Pharmacol., 27, 33 (1966).
Willits, C. O., Swain, M. W., Connelly, J. A., and Brice, B. A., Anal. Chem., 22, 430 (1950).
Grob, K., Beitr. Tabac. Forsch., No. 3, 97 (1961).
Albert, A., in Selective Toxicity, chapter 8 (Methuen, London, 1960).
Triggs, E. J., thesis, University of London, 159 (1967).
Turner, D. M., Biochem. J., 115, 889 (1969).
Armitage, A. K., and Milton, A. S., in Tobacco Alkaloids and Related Compounds (edit. by von Euler, U. S.), 205 (Pergamon, Oxford, 1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ARMITAGE, A., TURNER, D. Absorption of Nicotine in Cigarette and Cigar Smoke through the Oral Mucosa. Nature 226, 1231–1232 (1970). https://doi.org/10.1038/2261231a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/2261231a0
This article is cited by
-
Physical and chemical characterization of smokeless tobacco products in India
Scientific Reports (2023)
-
Direct analysis of free-base nicotine in tobacco leaf by headspace solid-phase micro-extraction combined with gas chromatography/mass spectrometry
Accreditation and Quality Assurance (2019)
-
Examining of Thallium in Cigarette Smokers
Biological Trace Element Research (2018)
-
Synthesis of graphene/DPA composite for determination of nicotine in tobacco products
Scientific Reports (2017)
-
Non-Cigarette Tobacco and the Lung
Clinical Reviews in Allergy & Immunology (2014)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.