Abstract
IT has been suggested that the immunological tolerance induced by parabiosing some strains of adult inbred mice with the F1 hybrid of a cross between that and another inbred strain sharing the same H–2 histocompatibility locus, but differing at weaker loci, is caused not only by a continuous exposure of the parental partner to transplantation antigens of the F1 partner but also to the establishment of cellular chimerism in the parental partner1–4 at least as far as the spleen is concerned—the lymphoid organ which has received most attention in this respect.
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NISBET, N. Immunological Tolerance in the Absence of Cellular Chimerism. Nature 214, 94–95 (1967). https://doi.org/10.1038/214094a0
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DOI: https://doi.org/10.1038/214094a0
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