Abstract
SEVERE nuclear vacuolation has been observed in the liver cells of human diabetics1–3, of infants suffering from malnutrition2 and of patients suffering from various diseases2–5, but has not been reported in experimental diabetes, whether produced by pancreatectomy or by alloxan in laboratory animals. The factors promoting nuclear vacuolation still await investigation.
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References
Warren, S., “The Pathology of Diabetes Mellitus” (2nd edit., Lea and Febiger, 1938).
Gillman, J., and Gillman, T., “Perspectives in Human Malnutrition”, 238, 305 (Grune and Stratton, 1951).
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Haex, A. J., de Jong, J. J., and van Beek, C., Nederl. Tijdschr. v. Geneesk., 87, 923 (1943).
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GILLMAN, J., GILBERT, C. Nuclear Vacuolation in the Liver Cells of Depancreatized Baboons. Nature 177, 666–667 (1956). https://doi.org/10.1038/177666a0
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DOI: https://doi.org/10.1038/177666a0
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