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Many structural features of the mammalian central nervous system can be explained by a morphogenetic mechanism that involves mechanical tension along axons, dendrites and glial processes. In the cerebral cortex, for example, tension along axons in the white matter can explain how and why the cortex folds in a characteristic species-specific pattern. In the cerebellum, tension along parallel fibres can explain why the cortex is highly elongated but folded like an accordion. By keeping the aggregate length of axonal and dendritic wiring low, tension should contribute to the compactness of neural circuitry throughout the adult brain.
Making only the assumption that you are a random intelligent observer, limits for the total longevity of our species of 0.2 million to 8 million years can be derived at the 95% confidence level. Further consideration indicates that we are unlikely to colonize the Galaxy, and that we are likely to have a higher population than the median for intelligent species.
We discuss evidence to show that the generally accepted view of the Big Bang model for the origin of the Universe is unsatisfactory. We suggest an alternative model that satisfies the constraints better.