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An electrochemical strategy is described in which the direct carboxylation of pyridines and related N-heteroarenes with CO2 shows divergent site selectivity depending on the type of reactor used.
A class of drugs that quash hunger have shown striking results in trials and in practice. But can they help all people with obesity — and conquer weight stigma?
Ferroelectricity has been found in a superconducting compound. Strong coupling between these two properties enables ferroelectric control of the superconductivity, which could prove useful for quantum devices.
Wallace, who independently discovered the theory of evolution, relied on local knowledge to craft his seminal work on species ranges in the Amazon. Now, the region’s Indigenous scientists have taken charge of their research using this and other cross-cultural tools.
The bacterial protein BlaR1 regulates resistance to β-lactam antibiotics in the multidrug-resistant bacteria, Staphylococcus aureus. Cryo-electron microscopy has revealed the detailed structures of BlaR1 in its resting state and in its β-lactam-bound activated state, illuminating possible routes to combating antibiotic resistance.
How does a fruit fly’s brain determine which way the animal should escape in the face of a looming predator? A mechanism involving numeric gradients of synaptic connections between neurons provides an answer.
Sophisticated experimental approaches reveal cellular and immune-system mechanisms that enable rare HIV-infected cells to persist for decades in people who are taking antiretroviral drugs.
Mouse and human embryos undergo similar developmental steps, but the exact timings differ. An analysis reveals that differences in metabolic activity set the timing of one such step on the road to formation of the vertebrae.
An analysis of more than 1,500 field observations has identified a collection of agricultural practices that can improve the use of nitrogen fertilizers — boosting crop yields while reducing environmental pollution.
Born 200 years ago, the evolutionary biologist experienced many setbacks during his career — none more severe than when he headed home with his precious collections from Brazil.